Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen
Wang, Bo, Yang, Chunning, Jin, Xiaofang, Du, Qun, Wu, Herren, Dall'Acqua, William, Mazor, Yariv
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
Improving target cell specificity using a novel monovalent bispecific IgG design
Mazor, Yariv, Oganesyan, Vaheh, Yang, Chunning, Hansen, Anna, Wang, Jihong, Liu, Hongji, Sachsenmeier, Kris, Carlson, Marcia, Gadre, Dhanesh V, Borrok, Martin Jack, Yu, Xiang-Qing, Dall'Acqua, William, Wu, Herren, Chowdhury, Partha Sarathi
Published in mAbs (04.03.2015)
Published in mAbs (04.03.2015)
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Journal Article
Conformation-selective rather than avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of WT1-pMHC low expressing cancer cells by anti-WT1-pMHC/CD3 T cell engagers
Walseng, Even, Wang, Bo, Yang, Chunning, Patel, Pooja, Zhao, Chihao, Zhang, Hanzhi, Zhao, Peng, Mazor, Yariv
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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Journal Article
Enhancement of Immune Effector Functions by Modulating IgG's Intrinsic Affinity for Target Antigen
Mazor, Yariv, Yang, Chunning, Borrok, M Jack, Ayriss, Joanne, Aherne, Karen, Wu, Herren, Dall'Acqua, William F
Published in PloS one (20.06.2016)
Published in PloS one (20.06.2016)
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Journal Article
IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with limited cytokine release
Schardt, John S, Walseng, Even, Le, Kim, Yang, Chunning, Shah, Pooja, Fu, Ying, Alam, Kausar, Kelton, Cathryn R, Gu, Yu, Huang, Fengying, Lin, Jia, Liu, Wenhai, Dippel, Andrew, Zhang, Hanzhi, Mulgrew, Kathy, Pryts, Stacy, Chennupati, Vijaykumar, Chen, Hung-Chang, Denham, Jessica, Chen, Xiaoru, Pradhan, Pallab, Wu, Yuling, Hardman, Colin, Zhao, Chihao, Kierny, Michael, Song, Yang, Dovedi, Simon J, Cemerski, Saso, Mazor, Yariv
Published in mAbs (31.12.2024)
Published in mAbs (31.12.2024)
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Journal Article
Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-Cλ interface
Bagert, John D, Oganesyan, Vaheh, Chiang, Chi-I, Iannotti, Mike, Lin, Jia, Yang, Chunning, Payne, Sterling, McMahon, Will, Edwards, Samuel, Dippel, Andrew, Hutchinson, Mark, Huang, Fengying, Aleti, Vineela, Niu, Chendi, Qian, Chen, Denham, Jessica, Ferreira, Sofia, Pradhan, Pallab, Penney, Mark, Wang, Chunlei, Liu, Wenhai, Walseng, Even, Mazor, Yariv
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Fault recognition of electric servo steering gear based on long and short-term memory neural network
Yixiang, Xu, Chunning, Yang
Published in 2020 International Conference on Unmanned Aircraft Systems (ICUAS) (01.09.2020)
Published in 2020 International Conference on Unmanned Aircraft Systems (ICUAS) (01.09.2020)
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Conference Proceeding
Deletions in the Transmembrane Domain of a Sindbis Virus Glycoprotein Alter Virus Infectivity, Stability, and Host Range
Hernandez, Raquel, Sinodis, Christine, Horton, Michelle, Ferreira, Davis, Yang, Chunning, Brown, Dennis T
Published in Journal of Virology (01.12.2003)
Published in Journal of Virology (01.12.2003)
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Journal Article
Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence
Mazor, Yariv, Sachsenmeier, Kris F., Yang, Chunning, Hansen, Anna, Filderman, Jessica, Mulgrew, Kathy, Wu, Herren, Dall’Acqua, William F.
Published in Scientific reports (09.01.2017)
Published in Scientific reports (09.01.2017)
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Journal Article
Cooperative Search of Multiple Robots with a Distributed Algorithm
Li, Chun, Yang, Chunning
Published in IECON 2018 - 44th Annual Conference of the IEEE Industrial Electronics Society (01.10.2018)
Published in IECON 2018 - 44th Annual Conference of the IEEE Industrial Electronics Society (01.10.2018)
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Conference Proceeding
Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1 + Activated T Cells
Dovedi, Simon J, Elder, Matthew J, Yang, Chunning, Sitnikova, Suzanne I, Irving, Lorraine, Hansen, Anna, Hair, James, Jones, Des C, Hasani, Sumati, Wang, Bo, Im, Seock-Ah, Tran, Ben, Subramaniam, Deepa S, Gainer, Shelby D, Vashisht, Kapil, Lewis, Arthur, Jin, Xiaofang, Kentner, Stacy, Mulgrew, Kathy, Wang, Yaya, Overstreet, Michael G, Dodgson, James, Wu, Yanli, Palazon, Asis, Morrow, Michelle, Rainey, Godfrey J, Browne, Gareth J, Neal, Frances, Murray, Thomas V, Toloczko, Aleksandra D, Dall'Acqua, William, Achour, Ikbel, Freeman, Daniel J, Wilkinson, Robert W, Mazor, Yariv
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Journal Article
Preclinical Evaluation of AZD6422, an Armored Chimeric Antigen Receptor T Cell Targeting CLDN18.2 in Gastric, Pancreatic, and Esophageal Cancer
Barrett, Allison M, Britton, Zachary T, Carrasco, Rosa A, Breen, Shannon, Broggi, Maria A S, Hatke, Amy, Clark, Benjamin, Yang, Chunning, Phipps, Sandrina, Ortiz, Lorenzo, Janocha, Brianna, Zanvit, Peter, Giraldo, Nicolas A, Martin, Philip L, Lapointe, Jean-Martin, Harder, Nathalie, Cornish, Georgina H, Attili, Bala N N R, Mazor, Yariv, Damschroder, Melissa, Cobbold, Mark, Moody, Gordon, Bosco, Emily E
Published in Clinical cancer research (25.09.2024)
Published in Clinical cancer research (25.09.2024)
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Journal Article
Insights into the molecular basis of a bispecific antibody's target selectivity
Mazor, Yariv, Hansen, Anna, Yang, Chunning, Chowdhury, Partha S, Wang, Jihong, Stephens, Geoffrey, Wu, Herren, Dall'Acqua, William F
Published in mAbs (04.05.2015)
Published in mAbs (04.05.2015)
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Journal Article
Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C λ interface
Bagert, John D, Oganesyan, Vaheh, Chiang, Chi-I, Iannotti, Mike, Lin, Jia, Yang, Chunning, Payne, Sterling, McMahon, Will, Edwards, Samuel, Dippel, Andrew, Hutchinson, Mark, Huang, Fengying, Aleti, Vineela, Niu, Chendi, Qian, Chen, Denham, Jessica, Ferreira, Sofia, Pradhan, Pallab, Penney, Mark, Wang, Chunlei, Liu, Wenhai, Walseng, Even, Mazor, Yariv
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Journal Article
A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response
Xiao, Zhan, Carrasco, Rosa A, Schifferli, Kevin, Kinneer, Krista, Tammali, Ravinder, Chen, Hong, Rothstein, Ray, Wetzel, Leslie, Yang, Chunning, Chowdhury, Partha, Tsui, Ping, Steiner, Philipp, Jallal, Bahija, Herbst, Ronald, Hollingsworth, Robert E, Tice, David A
Published in Molecular cancer therapeutics (01.04.2016)
Published in Molecular cancer therapeutics (01.04.2016)
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Journal Article
Abstract 5736: AZD9592: An EGFR-cMET bispecific antibody-drug conjugate (ADC) targeting key oncogenic drivers in non-small-cell lung cancer (NSCLC) and beyond
Comer, Frank, Mazor, Yariv, Hurt, Elaine, Yang, Chunning, Fleming, Ryan, Shandilya, Harini, Vijayakrishnan, Balakumar, Sterba, Meghan, Chen, Ruoyan, Rosfjord, Edward, Floch, Nicolas, Rosenbaum, Anton I., Huang, Yue, Yuan, Jiaqi, Beaumont, Kevin, Godfrey, Lisa, McGrath, Lara, Arnaldez, Fernanda, Sapra, Puja
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Element-tracing of mineral matters in Dendrobium officinale using ICP-MS and multivariate analysis
Zhu, Nannan, Han, Shen, Yang, Chunning, Qu, Jixu, Sun, Zhirong, Liu, Wenjie, Zhang, Xiaomin
Published in SpringerPlus (04.07.2016)
Published in SpringerPlus (04.07.2016)
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Journal Article
Structural insights into the interaction of human IgG1 with Fc[gamma]RI: no direct role of glycans in binding
Oganesyan, Vaheh, Mazor, Yariv, Yang, Chunning, Cook, Kimberly E, Woods, Robert M, Ferguson, Andrew, Bowen, Michael A, Martin, Tom, Zhu, Jie, Wu, Herren, Dall'Acqua, William F
Published in Acta crystallographica. Section D, Biological crystallography. (23.11.2015)
Published in Acta crystallographica. Section D, Biological crystallography. (23.11.2015)
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Journal Article