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Published in Cancer research (Chicago, Ill.) (01.11.2017)
Published in Cancer research (Chicago, Ill.) (01.11.2017)
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SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
Porstmann, Thomas, Santos, Claudio R., Griffiths, Beatrice, Cully, Megan, Wu, Mary, Leevers, Sally, Griffiths, John R., Chung, Yuen-Li, Schulze, Almut
Published in Cell metabolism (03.09.2008)
Published in Cell metabolism (03.09.2008)
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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
Bilanges, Benoit, Alliouachene, Samira, Pearce, Wayne, Morelli, Daniele, Szabadkai, Gyorgy, Chung, Yuen-Li, Chicanne, Gaëtan, Valet, Colin, Hill, Julia M., Voshol, Peter J., Collinson, Lucy, Peddie, Christopher, Ali, Khaled, Ghazaly, Essam, Rajeeve, Vinothini, Trichas, Georgios, Srinivas, Shankar, Chaussade, Claire, Salamon, Rachel S., Backer, Jonathan M., Scudamore, Cheryl L., Whitehead, Maria A., Keaney, Erin P., Murphy, Leon O., Semple, Robert K., Payrastre, Bernard, Tooze, Sharon A., Vanhaesebroeck, Bart
Published in Nature communications (27.11.2017)
Published in Nature communications (27.11.2017)
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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Published in Autophagy (02.06.2020)
Published in Autophagy (02.06.2020)
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A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity
Kostaras, Eleftherios, Kaserer, Teresa, Lazaro, Glorianne, Heuss, Sara Farrah, Hussain, Aasia, Casado, Pedro, Hayes, Angela, Yandim, Cihangir, Palaskas, Nicolaos, Yu, Yi, Schwartz, Brian, Raynaud, Florence, Chung, Yuen-Li, Cutillas, Pedro R., Vivanco, Igor
Published in British journal of cancer (18.08.2020)
Published in British journal of cancer (18.08.2020)
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PKB Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP
PORSTMANN, Thomas, GRIFFITHS, Beatrice, CHUNG, Yuen-Li, DELPUECH, Oona, GRIFFITHS, John R, DOWNWARD, Julian, SCHULZE, Almut
Published in Oncogene (29.09.2005)
Published in Oncogene (29.09.2005)
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Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation
Mayr, Manuel, MD, PhD, Yusuf, Shamil, MRCP, Weir, Graeme, MB, Chung, Yuen-Li, PhD, Mayr, Ursula, MD, Yin, Xiaoke, PhD, Ladroue, Christophe, PhD, Madhu, Basetti, MSc, PhD, Roberts, Neil, MB, De Souza, Ayesha, PhD, Fredericks, Salim, PhD, Stubbs, Marion, DPhil, Griffiths, John R., MB, BS, DPhil, Jahangiri, Marjan, MD, MRCS, Xu, Qingbo, MD, PhD, Camm, A. John, MD, FRCP, FACC
Published in Journal of the American College of Cardiology (05.02.2008)
Published in Journal of the American College of Cardiology (05.02.2008)
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Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma
Al-Saffar, Nada M. S., Troy, Helen, Wong Te Fong, Anne-Christine, Paravati, Roberta, Jackson, L. Elizabeth, Gowan, Sharon, Boult, Jessica K. R., Robinson, Simon P., Eccles, Suzanne A., Yap, Timothy A., Leach, Martin O., Chung, Yuen-Li
Published in British journal of cancer (30.10.2018)
Published in British journal of cancer (30.10.2018)
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Minimally Invasive Pharmacokinetic and Pharmacodynamic Technologies in Hypothesis-Testing Clinical Trials of Innovative Therapies
Workman, Paul, Aboagye, Eric O., Chung, Yuen-Li, Griffiths, John R., Hart, Rachel, Leach, Martin O., Maxwell, Ross J., McSheehy, Paul M. J., Price, Pat M., Zweit, Jamal
Published in JNCI : Journal of the National Cancer Institute (03.05.2006)
Published in JNCI : Journal of the National Cancer Institute (03.05.2006)
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Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism
O'Flaherty, Linda, Adam, Julie, Heather, Lisa C., Zhdanov, Alexander V., Chung, Yuen-Li, Miranda, Melroy X., Croft, Joanne, Olpin, Simon, Clarke, Kieran, Pugh, Christopher W., Griffiths, John, Papkovsky, Dmitri, Ashrafian, Houman, Ratcliffe, Peter J., Pollard, Patrick J.
Published in Human molecular genetics (01.10.2010)
Published in Human molecular genetics (01.10.2010)
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VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function
Briston, Thomas, Stephen, Jenna M, Thomas, Luke W, Esposito, Cinzia, Chung, Yuen-Li, Syafruddin, Saiful E, Turmaine, Mark, Maddalena, Lucas A, Greef, Basma, Szabadkai, Gyorgy, Maxwell, Patrick H, Vanharanta, Sakari, Ashcroft, Margaret
Published in Frontiers in oncology (04.10.2018)
Published in Frontiers in oncology (04.10.2018)
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Expression Profiling in Progressive Stages of Fumarate-Hydratase Deficiency: The Contribution of Metabolic Changes to Tumorigenesis
ASHRAFIAN, Houman, O'FLAHERTY, Linda, MIRANDA, Melroy, HOWARTH, Kimberley, SHUKLA, Deepa, TROY, Helen, GRIFFITHS, John, SPENCER-DENE, Bradley, YUSUF, Mohammed, VOLPI, Emanuela, MAXWELL, Patrick H, STAMP, Gordon, ADAM, Julie, POULSOM, Richard, PUGH, Christopher W, COSTA, Barbara, BARDELLA, Chiara, FLAVIA DI RENZO, Maria, KOTLIKOFF, Michael I, LAUNONEN, Virpi, AALTONEN, Lauri, EL-BAHRAWY, Mona, TOMLINSON, Ian, STEEPLES, Violetta, POLLARD, Patrick J, CHUNG, Yuen-Li, EAST, Phil, VANHARANTA, Sakari, LEHTONEN, Heli, NYE, Emma, HATIPOGLU, Emine
Published in Cancer research (Chicago, Ill.) (15.11.2010)
Published in Cancer research (Chicago, Ill.) (15.11.2010)
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Effects of HIF-1 and HIF2 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts
Biswas, Swethajit, Troy, Helen, Leek, Russell, Chung, Yuen-Li, Li, Ji-liang, Raval, Raju R., Turley, Helen, Gatter, Kevin, Pezzella, Francesco, Griffiths, John R., Stubbs, Marion, Harris, Adrian L.
Published in Journal of oncology (2010)
Published in Journal of oncology (2010)
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A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe
Weeks, Mark E., Sinclair, John, Butt, Amna, Chung, Yuen-Li, Worthington, Jessica L., Wilkinson, Caroline R. M., Griffiths, John, Jones, Nic, Waterfield, Michael D., Timms, John F.
Published in Proteomics (Weinheim) (01.05.2006)
Published in Proteomics (Weinheim) (01.05.2006)
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Vascular proteomics: Linking proteomic and metabolomic changes
Mayr, Manuel, Mayr, Ursula, Chung, Yuen-Li, Yin, Xiaoke, Griffiths, John R., Xu, Qingbo
Published in Proteomics (Weinheim) (01.12.2004)
Published in Proteomics (Weinheim) (01.12.2004)
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Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies
Lin, Gigin, Andrejeva, Gabriela, Wong Te Fong, Anne-Christine, Hill, Deborah K, Orton, Matthew R, Parkes, Harry G, Koh, Dow-Mu, Robinson, Simon P, Leach, Martin O, Eykyn, Thomas R, Chung, Yuen-Li
Published in PloS one (2014)
Published in PloS one (2014)
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Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas
Golinska, Monika, Troy, Helen, Chung, Yuen-Li, McSheehy, Paul M, Mayr, Manuel, Yin, Xiaoke, Ly, Lucy, Williams, Kaye J, Airley, Rachel E, Harris, Adrian L, Latigo, John, Perumal, Meg, Aboagye, Eric O, Perrett, David, Stubbs, Marion, Griffiths, John R
Published in BMC cancer (25.05.2011)
Published in BMC cancer (25.05.2011)
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