A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
Huang, William Y C, Alvarez, Steven, Kondo, Yasushi, Lee, Young Kwang, Chung, Jean K, Lam, Hiu Yue Monatrice, Biswas, Kabir H, Kuriyan, John, Groves, Jay T
Published in Science (American Association for the Advancement of Science) (08.03.2019)
Published in Science (American Association for the Advancement of Science) (08.03.2019)
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Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
Huang, William Y. C., Yan, Qingrong, Lin, Wan-Chen, Chung, Jean K., Hansen, Scott D., Christensen, Sune M., Tu, Hsiung-Lin, Kuriyan, John, Groves, Jay T.
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2016)
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Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate
Lee, Young Kwang, Low-Nam, Shalini T, Chung, Jean K, Hansen, Scott D, Lam, Hiu Yue Monatrice, Alvarez, Steven, Groves, Jay T
Published in Nature communications (28.04.2017)
Published in Nature communications (28.04.2017)
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Two-Dimensional IR Spectroscopy of Protein Dynamics Using Two Vibrational Labels: A Site-Specific Genetically Encoded Unnatural Amino Acid and an Active Site Ligand
Thielges, Megan C, Axup, Jun Y, Wong, Daryl, Lee, Hyun Soo, Chung, Jean K, Schultz, Peter G, Fayer, Michael D
Published in The journal of physical chemistry. B (29.09.2011)
Published in The journal of physical chemistry. B (29.09.2011)
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Direct observation of fast protein conformational switching
Ishikawa, Haruto, Kwak, Kyungwon, Chung, Jean K, Kim, Seongheun, Fayer, Michael D
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2008)
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Neuroglobin dynamics observed with ultrafast 2D-IR vibrational echo spectroscopy
Ishikawa, Haruto, Finkelstein, Ilya J, Kim, Seongheun, Kwak, Kyungwon, Chung, Jean K, Wakasugi, Keisuke, Massari, Aaron M, Fayer, Michael D
Published in Proceedings of the National Academy of Sciences - PNAS (09.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (09.10.2007)
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Oxidation Kinetics of Fluorescent Membrane Lipid Peroxidation Indicators
Jeong, Hye Jin, Picou, Cyrus, Jeong, Keunhong, Chung, Jean K.
Published in ACS chemical biology (16.08.2024)
Published in ACS chemical biology (16.08.2024)
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Journal Article
K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions
Chung, Jean K., Lee, Young Kwang, Denson, John-Paul, Gillette, William K., Alvarez, Steven, Stephen, Andrew G., Groves, Jay T.
Published in Biophysical journal (09.01.2018)
Published in Biophysical journal (09.01.2018)
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Journal Article
Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions
Chung, Jean K., Huang, William Y.C., Carbone, Catherine B., Nocka, Laura M., Parikh, Atul N., Vale, Ronald D., Groves, Jay T.
Published in Biophysical journal (06.04.2021)
Published in Biophysical journal (06.04.2021)
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Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization
Chung, Jean K., Nocka, Laura M., Decker, Aubrianna, Wang, Qi, Kadlecek, Theresa A., Weiss, Arthur, Kuriyan, John, Groves, Jay T.
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2019)
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Journal Article
Raf promotes dimerization of the Ras G-domain with increased allosteric connections
Packer, Morgan R, Parker, Jillian A, Chung, Jean K, Li, Zhenlu, Lee, Young Kwang, Cookis, Trinity, Guterres, Hugo, Alvarez, Steven, Hossain, Md Amin, Donnelly, Daniel P, Agar, Jeffrey N, Makowski, Lee, Buck, Matthias, Groves, Jay T, Mattos, Carla
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2021)
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Journal Article
Covalent Ras Dimerization on Membrane Surfaces through Photosensitized Oxidation
Chung, Jean K, Lee, Young Kwang, Lam, Hiu Yue Monatrice, Groves, Jay T
Published in Journal of the American Chemical Society (17.02.2016)
Published in Journal of the American Chemical Society (17.02.2016)
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