Targeting cancer stemness mediated by BMI1 and MCL1 for non‐small cell lung cancer treatment
Lin, Erh‐Hsuan, Hsu, Jhen‐Wei, Lee, Ting‐Fang, Hsu, Chiung‐Fang, Lin, Tsung‐Hsien, Jan, Yi‐Hua, Chang, Hsiang‐Yi, Cheng, Chun‐Ming, Hsu, Hui‐Jan, Chen, Wei‐Wei, Chen, Bo‐Hung, Tsai, Hsing‐Fang, Li, Jung‐Jung, Huang, Chi‐Ying, Chuang, Shih‐Hsien, Chang, Jia‐Ming, Hsiao, Michael, Wu, Cheng‐Wen
Published in Journal of cellular and molecular medicine (01.08.2022)
Published in Journal of cellular and molecular medicine (01.08.2022)
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Selective and predicable amine conjugation sites by kinetic characterization under excess reagents
Huang, Wei-Chun, Huang, Li-Juan, Hsu, Liang-Sheng, Huang, Shih-Ting, Lo, Wen-Ting, Wang, Tzu-Fan, Sun, Wei-Ting, Wei, Win-Yin, Lee, Ying-Shuan, Chuang, Shih-Hsien, Lee, Chao-Pin, Chou, Ho-Hsuan, Chen, Shu-Hui
Published in Scientific reports (27.10.2021)
Published in Scientific reports (27.10.2021)
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Taiwan's budgetary responses to COVID-19: the use of special budgets
Liao, Wei-Jie, Kuo, Nai-Ling, Chuang, Shih-Hsien
Published in Journal of public budgeting, accounting & financial management (26.01.2021)
Published in Journal of public budgeting, accounting & financial management (26.01.2021)
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Design, synthesis, and in vitro/vivo anticancer activity of 4‐substituted 7‐(3‐fluoro‐4‐methoxybenzyl)‐7H‐pyrrolo[2,3‐d]pyrimidines
Tsai, Pei‐Yi, Hu, Gong‐Siang, Huang, Po‐Hsun, Jheng, Huei‐Lin, Lan, Chi‐Hsuan, Chen, You‐Sin, Chang, Jia‐Ming, Chuang, Shih‐Hsien, Huang, Jiann‐Jyh
Published in Journal of the Chinese Chemical Society (Taipei) (01.09.2021)
Published in Journal of the Chinese Chemical Society (Taipei) (01.09.2021)
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The inhibition profiles of 4'‐acylpyrrole–5‐fluoroindolin‐2‐ones with a C‐3' side chain for VEGFR2, PDGFR‐β, and FGFR‐1 protein kinases
Huang, Jiann‐Jyh, Lin, Yu‐Hsiang, Lai, Chun‐Liang, Yang, Sheng‐Chuan, Lin, Shu Fu, Yang, Ju‐Ying, Huang, Hung‐Jyun, Liu, Chiawei, Wei, Win‐Yin, Chuang, Shih‐Hsien, Chiang, Chao‐Cheng, Lee, Ying‐Shuen E., Liao, Chu‐Bin, Chern, Ching Yuh
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2020)
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2020)
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Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1
Huang, Lynn Y L, Lee, Ying-Shuan, Huang, Jiann-Jyh, Chang, Chia-chi, Chang, Jia-Ming, Chuang, Shih-Hsien, Kao, Kuo-Jang, Tsai, Yung-Jen, Tsai, Pei-Yi, Liu, Chia-Wei, Lin, Her-Sheng, Lau, Johnson Y N
Published in Journal of experimental & clinical cancer research (09.01.2014)
Published in Journal of experimental & clinical cancer research (09.01.2014)
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Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries
Hsu, Hung-Ju, Tung, Chao-Ping, Yu, Chung-Ming, Chen, Chi-Yung, Chen, Hong-Sen, Huang, Yu-Chuan, Tsai, Pei-Hsun, Lin, Su-I, Peng, Hung-Pin, Chiu, Yi-Kai, Tsou, Yueh-Liang, Kuo, Wei-Ying, Jian, Jhih-Wei, Hung, Fei-Hung, Hsieh, Chiao-Yun, Hsiao, Michael, Chuang, Simon Shih-Hsien, Shen, Chia-Ning, Wang, Yong Alison, Yang, An-Suei
Published in Scientific reports (29.07.2021)
Published in Scientific reports (29.07.2021)
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Mirizzi Syndrome Complicated With Transverse Colon Fistula Presenting as Colonic Tumor: A Case Report and Literature Review
Chuang, Shih-Hsien, Chang, Ching-Wei, Chang, Chen-Wang, Chu, Cheng-Hsin, Hung, Chien-Yuan
Published in International journal of gerontology (01.09.2018)
Published in International journal of gerontology (01.09.2018)
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Aminyl and iminyl radicals from arylhydrazones in the photo-induced DNA cleavage
Ru Hwu, Jih, Chieh Lin, Chun, Hsien Chuang, Shih, Yung King, Ke, Su, Tzu-Rong, Tsay, Shwu-Chen
Published in Bioorganic & medicinal chemistry (15.05.2004)
Published in Bioorganic & medicinal chemistry (15.05.2004)
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D-420720, A novel orally active sulfonamide compound dipeptidyl peptidase IV inhibitor: structure and activity relationship of arylsulfonamide to dipeptidyl peptidase IV inhibition
Tsai, Henry J., Chou, Shan-Yen, Chuang, Shih-Hsien, Chen, Chien-Cheng, Hsu, Feng-Lin
Published in Drug development research (01.12.2008)
Published in Drug development research (01.12.2008)
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Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy
Chuang, Shih-Hsien, Lee, Ying-Shuan E., Huang, Lynn Y.L., Chen, Chi-Kuan, Lai, Chun-Liang, Lin, Yu-Hsiang, Yang, Ju-Ying, Yang, Sheng-Chuan, Chang, Lien-Hsiang, Chen, Ching-Hui, Liu, Chia-Wei, Lin, Her-Sheng, Lee, Yi-Ru, Huang, Kuan Pin, Fu, Kuo Chu, Jen, Hsueh-Min, Lai, Jun-Yu, Jian, Pei-Shiou, Wang, Yu-Chuan, Hsueh, Wen-Yun, Tsai, Pei-Yi, Hong, Wan-Hua, Chang, Chia-Chi, Wu, Diana ZC, Wu, Jinn, Chen, Meng-Hsin, Yu, Kuo-Ming, Chern, Ching Yuh, Chang, Jia-Ming, Lau, Johnson Y.N., Huang, Jiann-Jyh
Published in European journal of medicinal chemistry (01.04.2020)
Published in European journal of medicinal chemistry (01.04.2020)
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Design and synthesis of 4-anilinoquinazolines as Raf kinase inhibitors. Part 1. Selective B-Raf/B-Raf(V600E) and potent EGFR/VEGFR2 inhibitory 4-(3-hydroxyanilino)-6-(1H-1,2,3-triazol-4-yl)quinazolines
Lee, Cheng, Liao, Chu-Bin, Chen, Chih-Shang, Cheng, Fen-Ying, Chung, Yu-Hsuan, Wang, Yu-Chuan, Ciou, Sian-Yi, Hsueh, Wen-Yun, Lo, Tzu-Hao, Huang, Guan-Ru, Huang, Hsin-Yi, Tsai, Chia-Shen, Lu, Yu-Jung, Chuang, Shih-Hsien, Huang, Jiann-Jyh
Published in Bioorganic chemistry (01.04.2021)
Published in Bioorganic chemistry (01.04.2021)
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Copper(I)-Catalyzed Nitrile-Addition/ N -Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6 H -indolo[3,2- c ]quinolin-6-ones as Potent Topoisomerase-I Inhibitors
Hsueh, Wen-Yun, Lee, Ying-Shuan E, Huang, Min-Sian, Lai, Chin-Hung, Gao, Yu-Sheng, Lin, Jo-Chu, Chen, Yu-Fen, Chang, Chih-Lin, Chou, Shan-Yen, Chen, Shyh-Fong, Lu, Yann-Yu, Chang, Lien-Hsiang, Lin, Shu Fu, Lin, Yu-Hsiang, Hsu, Pi-Chen, Wei, Win-Yin, Huang, Ya-Chi, Kao, Yi-Feng, Teng, Li-Wei, Liu, Hung-Huang, Chen, Ying-Chou, Yuan, Ta-Tung, Chan, Ya-Wen, Huang, Po-Hsun, Chao, Yu-Ting, Huang, Shin-Yi, Jian, Bo-Han, Huang, Hsin-Yi, Yang, Sheng-Chuan, Lo, Tzu-Hao, Huang, Guan-Ru, Wang, Shao-Yun, Lin, Her-Sheng, Chuang, Shih-Hsien, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (11.02.2021)
Published in Journal of medicinal chemistry (11.02.2021)
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Journal Article
Discovery of 4‑Aryl‑N‑arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties
Lee, Ying-Shuan E, Chuang, Shih-Hsien, Huang, Lynn Y. L, Lai, Chun-Liang, Lin, Yu-Hsiang, Yang, Ju-Ying, Liu, Chia-Wei, Yang, Sheng-chuan, Lin, Her-Sheng, Chang, Chia-chi, Lai, Jun-Yu, Jian, Pei-Shiou, Lam, King, Chang, Jia-Ming, Lau, Johnson Y. N, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
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Journal Article
Discovery of Pyrrole−Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile
Chiang, Chao-Cheng, Lin, Yu-Hsiang, Lin, Shu Fu, Lai, Chun-Liang, Liu, Chiawei, Wei, Win-Yin, Yang, Sheng-chuan, Wang, Ru-Wen, Teng, Li-Wei, Chuang, Shih-Hsien, Chang, Jia-Ming, Yuan, Ta-Tung, Lee, Ying-Shuen, Chen, Paonien, Chi, Wei-Kuang, Yang, Ju-Ying, Huang, Hung-Jyun, Liao, Chu-Bin, Huang, Jiann-Jyh
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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Journal Article
Activity of a novel Hec1-targeted anticancer compound against breast cancer cell lines in vitro and in vivo
Huang, Lynn Y L, Chang, Chia-Chi, Lee, Ying-Shuan, Chang, Jia-Ming, Huang, Jiann-Jyh, Chuang, Shih-Hsien, Kao, Kuo-Jang, Lau, Gillian M G, Tsai, Pei-Yi, Liu, Chia-Wei, Lin, Her-Sheng, Lau, Johnson Y N
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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Inhibition of Hec1 as a novel approach for treatment of primary liver cancer
Huang, Lynn YL, Chang, Chia-chi, Lee, Ying-Shuan, Huang, Jiann-Jyh, Chuang, Shih-Hsien, Chang, Jia-Ming, Kao, Kuo-Jang, Lau, Gillian MG, Tsai, Pei-Yi, Liu, Chia-wei, Lin, Her-Sheng, Gish, Robert G., Lau, Johnson YN
Published in Cancer chemotherapy and pharmacology (01.09.2014)
Published in Cancer chemotherapy and pharmacology (01.09.2014)
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