CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy
Zhang, Xiang, Han, Juqiang, Man, Kwan, Li, Xiaoxing, Du, Jinghua, Chu, Eagle S.H, Go, Minnie Y.Y, Sung, Joseph J.Y, Yu, Jun
Published in Journal of hepatology (01.01.2016)
Published in Journal of hepatology (01.01.2016)
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Journal Article
CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis
Zhang, Xiang, Shen, Jiayun, Man, Kwan, Chu, Eagle S.H, Yau, Tung On, Sung, Joanne C.Y, Go, Minnie Y.Y, Deng, Jun, Lu, Liwei, Wong, Vincent W.S, Sung, Joseph J.Y, Farrell, Geoffrey, Yu, Jun
Published in Journal of hepatology (01.12.2014)
Published in Journal of hepatology (01.12.2014)
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Journal Article
Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice
Tsoi, Ho, Chu, Eagle S.H, Zhang, Xiang, Sheng, Jianqiu, Nakatsu, Daniel, Ng, Siew C, Chan, Anthony W.H, Chan, Francis K.L, Sung, Joseph J.Y, Yu, Jun
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2017)
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Journal Article
microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway
Wang, Jia, Chu, Eagle S H, Chen, Hai-Yong, Man, Kwan, Go, Minnie Y Y, Huang, Xiao Ru, Lan, Hui Yao, Sung, Joseph J Y, Yu, Jun
Published in Oncotarget (30.03.2015)
Published in Oncotarget (30.03.2015)
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Journal Article
Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation
Qian, Yun, Wong, Chi Chun, Xu, Jiaying, Chen, Huarong, Zhang, Yanquan, Kang, Wei, Wang, Hua, Zhang, Li, Li, Weilin, Chu, Eagle S H, Go, Minnie Y Y, Chiu, Philip W Y, Ng, Enders K W, Chan, Francis K L, Sung, Joseph J Y, Si, Jianmin, Yu, Jun
Published in Cancer research (Chicago, Ill.) (15.04.2017)
Published in Cancer research (Chicago, Ill.) (15.04.2017)
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Journal Article
High Sensitivity of Shotgun Metagenomic Sequencing in Colon Tissue Biopsy by Host DNA Depletion
Cheng, Wing Yin, Liu, Wei-Xin, Ding, Yanqiang, Wang, Guoping, Shi, Yu, Chu, Eagle S.H., Wong, Sunny, Sung, Joseph J.Y., Yu, Jun
Published in Genomics, proteomics & bioinformatics (01.12.2023)
Published in Genomics, proteomics & bioinformatics (01.12.2023)
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Journal Article
Peptostreptococcus Anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice
Ho, Tsoi, Chu, Eagle S.H, Zhang, Xiang, Sheng, Jianqiu, Nakatsu, Daniel, Ng, Siew C, Chan, Anthony W.H, Chan, Francis K, Sung, Joseph J, Yu, Jun
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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Journal Article
B cell CLL/lymphoma 6 member B inhibits hepatocellular carcinoma metastases in vitro and in mice
Wang, Jia, Dong, Ling, Xu, Lixia, Chu, Eagle S.H, Chen, Yangchao, Shen, Jiayun, Li, Xiaoxing, Wong, Chi Chun, Sung, Joseph J.Y, Yu, Jun
Published in Cancer letters (28.12.2014)
Published in Cancer letters (28.12.2014)
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Journal Article
Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro
Yu, Jun, Zhang, Sui, Chu, Eagle S.H., Go, Minnie Y.Y., Lau, Rebecca H.Y., Zhao, Junhong, Wu, Chung-Wah, Tong, Lixin, Zhao, Jingmin, Poon, Terence C.W., Sung, Joseph J.Y.
Published in The international journal of biochemistry & cell biology (01.06.2010)
Published in The international journal of biochemistry & cell biology (01.06.2010)
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Journal Article
Heme oxygenase-1 protects against steatohepatitis in both cultured hepatocytes and mice
Yu, Jun, Chu, Eagle S H, Wang, Ruizhi, Wang, Shiyan, Wu, Chung W, Wong, Vincent W S, Chan, Henry L Y, Farrell, Geofferey C, Sung, Joseph J Y
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2010)
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Quantitative detection of methylated SOCS-1, a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection
CHAN, Michael W. Y, CHU, Eagle S. H, TO, Ka-Fai, LEUNG, Wai K
Published in Biotechnology letters (01.08.2004)
Published in Biotechnology letters (01.08.2004)
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Journal Article
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites
Zhang, Xiang, Coker, Olabisi Oluwabukola, Chu, Eagle SH, Fu, Kaili, Lau, Harry C H, Wang, Yi-Xiang, Chan, Anthony W H, Wei, Hong, Yang, Xiaoyong, Sung, Joseph J Y, Yu, Jun
Published in Gut (01.04.2021)
Published in Gut (01.04.2021)
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Journal Article
Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling
Liang, Jessie Qiaoyi, Teoh, Narcissus, Xu, Lixia, Pok, Sharon, Li, Xiangchun, Chu, Eagle S H, Chiu, Jonathan, Dong, Ling, Arfianti, Evi, Haigh, W Geoffrey, Yeh, Matthew M, Ioannou, George N, Sung, Joseph J Y, Farrell, Geoffrey, Yu, Jun
Published in Nature communications (26.10.2018)
Published in Nature communications (26.10.2018)
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Journal Article
Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity
Long, Xiaohang, Wong, Chi Chun, Tong, Li, Chu, Eagle S H, Ho Szeto, Chun, Go, Minne Y Y, Coker, Olabisi Oluwabukola, Chan, Anthony W H, Chan, Francis K L, Sung, Joseph J Y, Yu, Jun
Published in Nature microbiology (01.12.2019)
Published in Nature microbiology (01.12.2019)
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Journal Article
Altered gut microbiome composition by appendectomy contributes to colorectal cancer
Shi, Feiyu, Liu, Gaixia, Lin, Yufeng, Guo, Cosmos Liutao, Han, Jing, Chu, Eagle S H, Shi, Chengxin, Li, Yaguang, Zhang, Haowei, Hu, Chenhao, Liu, Ruihan, He, Shuixiang, Guo, Gang, Chen, Yinnan, Zhang, Xiang, Coker, Olabisi Oluwabukola, Wong, Sunny Hei, Yu, Jun, She, Junjun
Published in Oncogene (10.02.2023)
Published in Oncogene (10.02.2023)
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Journal Article
High Soluble Fiber Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites in Mice
Yang, Jia, Wei, Hong, Lin, Yufeng, Chu, Eagle S H, Zhou, Yunfei, Gou, Hongyan, Guo, Shang, Lau, Harry C H, Cheung, Alvin H K, Chen, Huarong, To, Ka Fei, Sung, Joseph J Y, Wang, Yong, Yu, Jun
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2024)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2024)
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Fecal microbial DNA markers serve for screening colorectal neoplasm in asymptomatic subjects
Liang, Jessie Qiaoyi, Wong, Sunny H, Szeto, Chun Ho, Chu, Eagle SH, Lau, Harry C, Chen, Yingxuan, Fang, Jingyuan, Yu, Jun, Sung, Joseph JY
Published in Journal of gastroenterology and hepatology (01.04.2021)
Published in Journal of gastroenterology and hepatology (01.04.2021)
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Journal Article
Bone marrow‐derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells
Han, Juqiang, Zhang, Xiang, Lau, Jennie K‐C, Fu, Kaili, Lau, Harry CH, Xu, Weiqi, Chu, Eagle SH, Lan, Huiyao, Yu, Jun
Published in The Journal of pathology (01.08.2019)
Published in The Journal of pathology (01.08.2019)
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Journal Article
Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
Huang, Pingmei, Ji, Fenfen, Cheung, Alvin Ho-Kwan, Fu, Kaili, Zhou, Qiming, Ding, Xiao, Chen, Danyu, Lin, Yufeng, Wang, Luyao, Jiao, Ying, Chu, Eagle S.H., Kang, Wei, To, Ka Fai, Yu, Jun, Wong, Chi Chun
Published in Cell host & microbe (14.08.2024)
Published in Cell host & microbe (14.08.2024)
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Journal Article
Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis
Wang, Xiaojuan, Zhang, Xiang, Chu, Eagle S H, Chen, Xiaoting, Kang, Wei, Wu, Feng, To, Ka-Fai, Wong, Vincent W S, Chan, Henry L Y, Chan, Matthew T V, Sung, Joseph J Y, Wu, William K K, Yu, Jun
Published in The FASEB journal (01.01.2018)
Published in The FASEB journal (01.01.2018)
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