Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience
O'Brien, Susan, Furman, Richard R., Coutre, Steven, Flinn, Ian W., Burger, Jan A., Blum, Kristie, Sharman, Jeff, Wierda, William, Jones, Jeffrey, Zhao, Weiqiang, Heerema, Nyla A., Johnson, Amy J., Luan, Ying, James, Danelle F., Chu, Alvina D., Byrd, John C.
Published in Blood (26.04.2018)
Published in Blood (26.04.2018)
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Journal Article
Upadacitinib plus topical corticosteroids in atopic dermatitis: Week 52 AD Up study results
Silverberg, Jonathan I., de Bruin-Weller, Marjolein, Bieber, Thomas, Soong, Weily, Kabashima, Kenji, Costanzo, Antonio, Rosmarin, David, Lynde, Charles, Liu, John, Gamelli, Amy, Zeng, Jiewei, Ladizinski, Barry, Chu, Alvina D., Reich, Kristian
Published in Journal of allergy and clinical immunology (01.03.2022)
Published in Journal of allergy and clinical immunology (01.03.2022)
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Journal Article
Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
O'Brien, Susan, Prof, Jones, Jeffrey A, MD, Coutre, Steven E, Prof, Mato, Anthony R, MD, Hillmen, Peter, Prof, Tam, Constantine, MD, Österborg, Anders, Prof, Siddiqi, Tanya, MD, Thirman, Michael J, MD, Furman, Richard R, MD, Ilhan, Osman, Prof, Keating, Michael J, Prof, Call, Timothy G, MD, Brown, Jennifer R, MD, Stevens-Brogan, Michelle, MSc, Li, Yunfeng, PhD, Clow, Fong, ScD, James, Danelle F, MD, Chu, Alvina D, MD, Hallek, Michael, Prof, Stilgenbauer, Stephan, Prof
Published in The lancet oncology (01.10.2016)
Published in The lancet oncology (01.10.2016)
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Journal Article
Tetramers reveal IL-17–secreting CD4⁺ T cells that are specific for U1-70 in lupus and mixed connective tissue disease
Kattah, Nicole H., Newell, Evan W., Jarrell, Justin Ansel, Chu, Alvina D., Xie, Jianming, Kattah, Michael G., Goldberger, Ofir, Ye, Jessica, Chakravarty, Eliza F., Davis, Mark M., Utz, Paul J.
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2015)
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Journal Article
IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice
Thibault, Donna L, Chu, Alvina D, Graham, Kareem L, Balboni, Imelda, Lee, Lowen Y, Kohlmoos, Cassidy, Landrigan, Angela, Higgins, John P, Tibshirani, Robert, Utz, Paul J
Published in The Journal of clinical investigation (01.04.2008)
Published in The Journal of clinical investigation (01.04.2008)
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Journal Article
Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial
Reich, Kristian, Teixeira, Henrique D, de Bruin-Weller, Marjolein, Bieber, Thomas, Soong, Weily, Kabashima, Kenji, Werfel, Thomas, Zeng, Jiewei, Huang, Xiaohong, Hu, Xiaofei, Hendrickson, Barbara A, Ladizinski, Barry, Chu, Alvina D, Silverberg, Jonathan I
Published in The Lancet (British edition) (05.06.2021)
Published in The Lancet (British edition) (05.06.2021)
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Journal Article
Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial
van der Heijde, Désirée, Song, In-Ho, Pangan, Aileen L, Deodhar, Atul, van den Bosch, Filip, Maksymowych, Walter P, Kim, Tae-Hwan, Kishimoto, Mitsumasa, Everding, Andrea, Sui, Yunxia, Wang, Xin, Chu, Alvina D, Sieper, Joachim
Published in The Lancet (British edition) (07.12.2019)
Published in The Lancet (British edition) (07.12.2019)
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Journal Article
Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials
Guttman-Yassky, Emma, Teixeira, Henrique D, Simpson, Eric L, Papp, Kim A, Pangan, Aileen L, Blauvelt, Andrew, Thaçi, Diamant, Chu, Chia-Yu, Hong, H Chih-ho, Katoh, Norito, Paller, Amy S, Calimlim, Brian, Gu, Yihua, Hu, Xiaofei, Liu, Meng, Yang, Yang, Liu, John, Tenorio, Allan R, Chu, Alvina D, Irvine, Alan D
Published in The Lancet (British edition) (05.06.2021)
Published in The Lancet (British edition) (05.06.2021)
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Journal Article
Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial
Blauvelt, Andrew, Teixeira, Henrique D, Simpson, Eric L, Costanzo, Antonio, De Bruin-Weller, Marjolein, Barbarot, Sebastien, Prajapati, Vimal H, Lio, Peter, Hu, Xiaofei, Wu, Tianshuang, Liu, John, Ladizinski, Barry, Chu, Alvina D, Eyerich, Kilian
Published in JAMA dermatology (Chicago, Ill.) (01.09.2021)
Published in JAMA dermatology (Chicago, Ill.) (01.09.2021)
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Journal Article
Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis: Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials
Simpson, Eric L, Papp, Kim A, Blauvelt, Andrew, Chu, Chia-Yu, Hong, H Chih-Ho, Katoh, Norito, Calimlim, Brian M, Thyssen, Jacob P, Chiou, Albert S, Bissonnette, Robert, Stein Gold, Linda F, Wegzyn, Colleen, Hu, Xiaofei, Liu, Meng, Liu, John, Tenorio, Allan R, Chu, Alvina D, Guttman-Yassky, Emma
Published in JAMA dermatology (Chicago, Ill.) (01.04.2022)
Published in JAMA dermatology (Chicago, Ill.) (01.04.2022)
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Journal Article
Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis
Ismail, Mohamed, Doelger, Eva, Eckert, Doerthe, Irvine, Alan D, Chu, Alvina D, Teixeira, Henrique D, Liu, Wei, Nader, Ahmed
Published in British journal of clinical pharmacology (01.10.2023)
Published in British journal of clinical pharmacology (01.10.2023)
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Journal Article
Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One‐Year Results of a Double‐Blind, Placebo‐Controlled Study and Open‐Label Extension
Deodhar, Atul, Heijde, Désirée, Sieper, Joachim, Van den Bosch, Filip, Maksymowych, Walter P., Kim, Tae‐Hwan, Kishimoto, Mitsumasa, Ostor, Andrew, Combe, Bernard, Sui, Yunxia, Chu, Alvina D., Song, In‐Ho
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2022)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2022)
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Journal Article
Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies
Guttman-Yassky, Emma, Thyssen, Jacob P., Silverberg, Jonathan I., Papp, Kim A., Paller, Amy S., Weidinger, Stephan, Chih-ho Hong, H., Hendrickson, Barbara, Dilley, Deanne, Tenorio, Allan R., Ladizinski, Barry, Chu, Alvina D., Liu, John, Irvine, Alan D.
Published in Journal of allergy and clinical immunology (01.01.2023)
Published in Journal of allergy and clinical immunology (01.01.2023)
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Journal Article
Pharmacokinetics, Safety, Tolerability, and Exploratory Efficacy of Upadacitinib in Children with Severe Atopic Dermatitis
Qian, Yuli, Raymundo, Eliza M., Hao, Shuai, Unnebrink, Kristina, Levy, Gweneth F., Teixeira, Henrique D., Chu, Alvina D., Zinn, Zachary A., Paller, Amy S., Liu, Wei, Mohamed, Mohamed-Eslam F.
Published in Clinical therapeutics (01.10.2024)
Published in Clinical therapeutics (01.10.2024)
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Journal Article
A phase 3 randomized, multicenter, double-blind study to evaluate the safety of upadacitinib in combination with topical corticosteroids in adolescent and adult patients with moderate-to-severe atopic dermatitis in Japan (Rising Up): An interim 24-week analysis
Katoh, Norito, Ohya, Yukihiro, Murota, Hiroyuki, Ikeda, Masanori, Hu, Xiaofei, Ikeda, Kimitoshi, Liu, John, Sasaki, Takuya, Chu, Alvina D., Teixeira, Henrique D., Saeki, Hidehisa
Published in JAAD international (01.03.2022)
Published in JAAD international (01.03.2022)
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Journal Article
Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic leukaemia treated with ibrutinib from 3 clinical trials
Jones, Jeffrey, Mato, Anthony, Coutre, Steven, Byrd, John C., Furman, Richard R., Hillmen, Peter, Osterborg, Anders, Tam, Constantine, Stilgenbauer, Stephan, Wierda, William G., Heerema, Nyla A., Eckert, Karl, Clow, Fong, Zhou, Cathy, Chu, Alvina D., James, Danelle F., O'Brien, Susan M.
Published in British journal of haematology (01.08.2018)
Published in British journal of haematology (01.08.2018)
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Journal Article
Measuring outcomes in systemic lupus erythematosus clinical trials
Strand, Vibeke, Chu, Alvina D
Published in Expert review of pharmacoeconomics & outcomes research (01.08.2011)
Published in Expert review of pharmacoeconomics & outcomes research (01.08.2011)
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Journal Article
Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling
HUILIAN QIN, LEE, I-Fang, PANAGIOTOPOULOS, Constadina, XIAOXIA WANG, CHU, Alvina D, UTZ, Paul J, PRIATEL, John J, RUSUNG TAN
Published in Diabetes (New York, N.Y.) (01.03.2011)
Published in Diabetes (New York, N.Y.) (01.03.2011)
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Journal Article
Development of Th17‐Associated Interstitial Kidney Inflammation in Lupus‐Prone Mice Lacking the Gene Encoding STAT‐1
Yiu, Gloria, Rasmussen, Tue K., Ajami, Bahareh, Haddon, David J., Chu, Alvina D., Tangsombatvisit, Stephanie, Haynes, Winston A., Diep, Vivian, Steinman, Larry, Faix, James, Utz, Paul J.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
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