Concepts for agonistic targeting of CD40 in immuno-oncology
Richards, David M., Sefrin, Julian P., Gieffers, Christian, Hill, Oliver, Merz, Christian
Published in Human vaccines & immunotherapeutics (01.02.2020)
Published in Human vaccines & immunotherapeutics (01.02.2020)
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Journal Article
The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy
Frankish, Jamie, Mukherjee, Debayan, Romano, Erminia, Billian-Frey, Katharina, Schröder, Matthias, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Honeychurch, Jamie, Illidge, Tim, Sykora, Jaromir
Published in Frontiers in immunology (26.05.2023)
Published in Frontiers in immunology (26.05.2023)
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Journal Article
Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma
Kleber, Susanne, Sancho-Martinez, Ignacio, Wiestler, Benedict, Beisel, Alexandra, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Mueller, Wolf, Sykora, Jaromir, Kuhn, Andreas, Schreglmann, Nina, Letellier, Elisabeth, Zuliani, Cecilia, Klussmann, Stefan, Teodorczyk, Marcin, Gröne, Hermann-Josef, Ganten, Tom M., Sültmann, Holger, Tüttenberg, Jochen, von Deimling, Andreas, Regnier-Vigouroux, Anne, Herold-Mende, Christel, Martin-Villalba, Ana
Published in Cancer cell (01.03.2008)
Published in Cancer cell (01.03.2008)
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Correction: CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells
Drachsler, Moritz, Kleber, Susanne, Mateos, Alvaro, Volk, Katrin, Mohr, Nadine, Chen, Si, Cirovic, Branko, Tüttenberg, Jochen, Gieffers, Christian, Sykora, Jaromir, Wirtz, Christian, Mueller, Wolf, Synowitz, Michael, Martin-Villalba, Ana
Published in Cell death & disease (22.07.2020)
Published in Cell death & disease (22.07.2020)
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Journal Article
Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma
Blaes, Jonas, Thomé, Carina M, Pfenning, Philipp-Niclas, Rübmann, Petra, Sahm, Felix, Wick, Antje, Bunse, Theresa, Schmenger, Torsten, Sykora, Jaromir, von Deimling, Andreas, Wiestler, Benedikt, Merz, Christian, Jugold, Manfred, Haberkorn, Uwe, Abdollahi, Amir, Debus, Jürgen, Gieffers, Christian, Kunz, Claudia, Bendszus, Martin, Kluge, Michael, Platten, Michael, Fricke, Harald, Wick, Wolfgang, Lemke, Dieter
Published in Molecular cancer research (01.05.2018)
Published in Molecular cancer research (01.05.2018)
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Journal Article
The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair
Corsini, Nina S., Sancho-Martinez, Ignacio, Laudenklos, Sabrina, Glagow, Désirée, Kumar, Sachin, Letellier, Elisabeth, Koch, Philipp, Teodorczyk, Marcin, Kleber, Susanne, Klussmann, Stefan, Wiestler, Benedict, Brüstle, Oliver, Mueller, Wolf, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Seedorf, Matthias, Gretz, Norbert, Sprengel, Rolf, Celikel, Tansu, Martin-Villalba, Ana
Published in Cell stem cell (07.08.2009)
Published in Cell stem cell (07.08.2009)
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Journal Article
HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality
Richards, David M, Marschall, Viola, Billian-Frey, Katharina, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Sefrin, Julian P, Schröder, Matthias, Sykora, Jaromir, Fricke, Harald, Hill, Oliver, Gieffers, Christian, Thiemann, Meinolf
Published in Journal for immunotherapy of cancer (19.07.2019)
Published in Journal for immunotherapy of cancer (19.07.2019)
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Journal Article
A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity
Thiemann, Meinolf, Richards, David M, Heinonen, Karl, Kluge, Michael, Marschall, Viola, Merz, Christian, Redondo Müller, Mauricio, Schnyder, Tim, Sefrin, Julian P, Sykora, Jaromir, Fricke, Harald, Gieffers, Christian, Hill, Oliver
Published in Frontiers in oncology (19.09.2018)
Published in Frontiers in oncology (19.09.2018)
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Journal Article
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
Petersen, B O, Wagener, C, Marinoni, F, Kramer, E R, Melixetian, M, Lazzerini Denchi, E, Gieffers, C, Matteucci, C, Peters, J M, Helin, K
Published in Genes & development (15.09.2000)
Published in Genes & development (15.09.2000)
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Journal Article
The RING-H2 Finger Protein APC11 and the E2 Enzyme UBC4 Are Sufficient to Ubiquitinate Substrates of the Anaphase-Promoting Complex
Gmachl, Michael, Gieffers, Christian, Podtelejnikov, Alexandre V., Mann, Matthias, Peters, Jan-Michael
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2000)
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Journal Article
Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family
Kramer, Edgar R., Gieffers, Christian, Hölzl, Gabriele, Hengstschläger, Markus, Peters, Jan-Michael
Published in Current biology (05.11.1998)
Published in Current biology (05.11.1998)
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Journal Article
Three-Dimensional Structure of the Anaphase-Promoting Complex
Gieffers, Christian, Dube, Prakash, Harris, J.Robin, Stark, Holger, Peters, Jan-Michael
Published in Molecular cell (01.04.2001)
Published in Molecular cell (01.04.2001)
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Journal Article
Characterization of the DOC1/APC10 Subunit of the Yeast and the Human Anaphase-promoting Complex
Grossberger, Rupert, Gieffers, Christian, Zachariae, Wolfgang, Podtelejnikov, Alexandre V., Schleiffer, Alexander, Nasmyth, Kim, Mann, Matthias, Peters, Jan-Michael
Published in The Journal of biological chemistry (14.05.1999)
Published in The Journal of biological chemistry (14.05.1999)
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Journal Article
Abstract 4529: Neutralization of pro-apoptotic CD95L by Asunercept/APG101 does not impair anti-tumor immune responses
Merz, Christian, Sykora, Jaromir, Hussong, Rebecca, Thiemann, Meinolf, Hill, Oliver, Gieffers, Christian
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1587: Generation and characterization of novel bispecific molecules combining single-chain-CD40L with anti-CEA, anti-CD95L or anti-PD-L1 targeting moieties
Schroeder, Matthias, Billian-Frey, Katharina, Sykora, Jaromir, Redondo-Mueller, Mauricio, Heinonen, Karl, Frankish, Jamie, Gieffers, Christian, Thiemann, Meinolf, Hill, Oliver
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
CD95L and Anti-Tumor Immune Response: Current Understanding and New Evidence
Richards, David M, Merz, Christian, Gieffers, Christian, Krendyukov, Andriy
Published in Cancer management and research (31.03.2021)
Published in Cancer management and research (31.03.2021)
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Journal Article
APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors
Gieffers, Christian, Kluge, Michael, Merz, Christian, Sykora, Jaromir, Thiemann, Meinolf, Schaal, René, Fischer, Carmen, Branschädel, Marcus, Abhari, Behnaz Ahangarian, Hohenberger, Peter, Fulda, Simone, Fricke, Harald, Hill, Oliver
Published in Molecular cancer therapeutics (01.12.2013)
Published in Molecular cancer therapeutics (01.12.2013)
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