Gene replacement therapy in a model of Charcot-Marie-Tooth 4C neuropathy
Schiza, Natasa, Georgiou, Elena, Kagiava, Alexia, Médard, Jean-Jacques, Richter, Jan, Tryfonos, Christina, Sargiannidou, Irene, Heslegrave, Amanda J, Rossor, Alexander M, Zetterberg, Henrik, Reilly, Mary M, Christodoulou, Christina, Chrast, Roman, Kleopa, Kleopas A
Published in Brain (London, England : 1878) (01.05.2019)
Published in Brain (London, England : 1878) (01.05.2019)
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Journal Article
Molecular Genetics of Charcot-Marie-Tooth Disease: From Genes to Genomes
Azzedine, H., Senderek, J., Rivolta, C., Chrast, R.
Published in Molecular syndromology (01.11.2012)
Published in Molecular syndromology (01.11.2012)
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Journal Article
A large multiexonic genomic deletion within the ALMS1 gene causes Alström syndrome in a consanguineous Pakistani family
Nikopoulos, K., Butt, G. U., Farinelli, P., Mudassar, M., Domènech-Estévez, E., Samara, C., Kausar, M., Masroor, I., Chrast, R., Rivolta, C., Siddiqi, S.
Published in Clinical genetics (01.04.2016)
Published in Clinical genetics (01.04.2016)
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Journal Article
The mouse brain transcriptome by SAGE: differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals
Chrast, R, Scott, H S, Papasavvas, M P, Rossier, C, Antonarakis, E S, Barras, C, Davisson, M T, Schmidt, C, Estivill, X, Dierssen, M, Pritchard, M, Antonarakis, S E
Published in Genome research (01.12.2000)
Published in Genome research (01.12.2000)
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Journal Article
Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome
CHRAST, R, SCOTT, H. S, MADANI, R, HUBER, L, WOLFER, D. P, PRINZ, M, AGUZZI, A, LIPP, H.-P, ANTONARAKIS, S. E
Published in Human molecular genetics (22.07.2000)
Published in Human molecular genetics (22.07.2000)
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Journal Article
The dark side of the brain, myelinating glia in central and peripheral nervous systems
Chrast, Roman, Castelo-Branco, Gonçalo
Published in Seminars in cell & developmental biology (01.08.2021)
Published in Seminars in cell & developmental biology (01.08.2021)
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Journal Article
Oligodendroglial myelination requires astrocyte-derived lipids
Camargo, Nutabi, Goudriaan, Andrea, van Deijk, Anne-Lieke F, Otte, Willem M, Brouwers, Jos F, Lodder, Hans, Gutmann, David H, Nave, Klaus-Armin, Dijkhuizen, Rick M, Mansvelder, Huibert D, Chrast, Roman, Smit, August B, Verheijen, Mark H G
Published in PLoS biology (26.05.2017)
Published in PLoS biology (26.05.2017)
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Journal Article
Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region
Chrast, R, Scott, H S, Chen, H, Kudoh, J, Rossier, C, Minoshima, S, Wang, Y, Shimizu, N, Antonarakis, S E
Published in Genome research (01.06.1997)
Published in Genome research (01.06.1997)
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Journal Article
Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS
Domènech-Estévez, Enric, Baloui, Hasna, Meng, Xiaosong, Zhang, Yanqing, Deinhardt, Katrin, Dupree, Jeff L, Einheber, Steven, Chrast, Roman, Salzer, James L
Published in The Journal of neuroscience (20.04.2016)
Published in The Journal of neuroscience (20.04.2016)
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Journal Article
Coordinated effects monitoring and modelling for developing and supporting international air pollution control agreements
BULL, K. R, ACHERMANN, B, HETTELINGH, J.-P, JOHANNESSEN, T, KRZYZANOWSKI, M, KUCERA, V, KVAEVEN, B, LORENZ, M, LUNDIN, L, MILLS, G, POSCH, M, SKJELKVALE, B. L, BASHKIN, V, ULSTEIN, M. J, CHRAST, R, FENECH, G, FORSIUS, M, GREGOR, H.-D, GUARDANS, R, HAUSSMANN, T, HAYES, F
Published in Water, air and soil pollution (01.08.2001)
Published in Water, air and soil pollution (01.08.2001)
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Conference Proceeding
Journal Article
Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy
Bernard-Marissal, Nathalie, van Hameren, Gerben, Juneja, Manisha, Pellegrino, Christophe, Louhivuori, Lauri, Bartesaghi, Luca, Rochat, Cylia, El Mansour, Omar, Médard, Jean-Jacques, Croisier, Marie, Maclachlan, Catherine, Poirot, Olivier, Uhlén, Per, Timmerman, Vincent, Tricaud, Nicolas, Schneider, Bernard L., Chrast, Roman
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
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Journal Article
Lipin1 is required for skeletal muscle development by regulating MEF2c and MyoD expression
Jama, Abdulrahman, Huang, Dengtong, Alshudukhi, Abdullah A., Chrast, Roman, Ren, Hongmei
Published in The Journal of physiology (01.02.2019)
Published in The Journal of physiology (01.02.2019)
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Journal Article
Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end‐plate innervation
Bouçanova, Filipa, Pollmeier, Gill, Sandor, Katalin, Morado Urbina, Carlos, Nijssen, Jik, Médard, Jean‐Jacques, Bartesaghi, Luca, Pellerin, Luc, Svensson, Camilla I, Hedlund, Eva, Chrast, Roman
Published in Glia (01.01.2021)
Published in Glia (01.01.2021)
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Journal Article
Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration
Vaquié, Adrien, Sauvain, Alizée, Duman, Mert, Nocera, Gianluigi, Egger, Boris, Meyenhofer, Felix, Falquet, Laurent, Bartesaghi, Luca, Chrast, Roman, Lamy, Christophe Maurice, Bang, Seokyoung, Lee, Seung-Ryeol, Jeon, Noo Li, Ruff, Sophie, Jacob, Claire
Published in Cell reports (Cambridge) (11.06.2019)
Published in Cell reports (Cambridge) (11.06.2019)
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Journal Article
Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor
Hor, Hyun, Francescatto, Ludmila, Bartesaghi, Luca, Ortega-Cubero, Sara, Kousi, Maria, Lorenzo-Betancor, Oswaldo, Jiménez-Jiménez, Felix J, Gironell, Alexandre, Clarimón, Jordi, Drechsel, Oliver, Agúndez, José A G, Kenzelmann Broz, Daniela, Chiquet-Ehrismann, Ruth, Lleó, Alberto, Coria, Francisco, García-Martin, Elena, Alonso-Navarro, Hortensia, Martí, Maria J, Kulisevsky, Jaume, Hor, Charlotte N, Ossowski, Stephan, Chrast, Roman, Katsanis, Nicholas, Pastor, Pau, Estivill, Xavier
Published in Human molecular genetics (15.10.2015)
Published in Human molecular genetics (15.10.2015)
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Journal Article
Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells
Deck, Marie, Van Hameren, Gerben, Campbell, Graham, Bernard-Marissal, Nathalie, Devaux, Jérôme, Berthelot, Jade, Lattard, Alise, Médard, Jean-Jacques, Gautier, Benoît, Guelfi, Sophie, Abbou, Scarlette, Quintana, Patrice, Chao de la Barca, Juan Manuel, Reynier, Pascal, Lenaers, Guy, Chrast, Roman, Tricaud, Nicolas
Published in PloS one (04.10.2022)
Published in PloS one (04.10.2022)
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Journal Article