Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence
Chow, Hei-Man, Shi, Meng, Cheng, Aifang, Gao, Yuehong, Chen, Guimiao, Song, Xuan, So, Raphaella Wai Lam, Zhang, Jie, Herrup, Karl
Published in Nature neuroscience (01.11.2019)
Published in Nature neuroscience (01.11.2019)
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Journal Article
Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease
Zhang, Ying, Zhang, Zhongyu, Li, Lianwei, Xu, Kaiyu, Ma, Zhanshan, Chow, Hei-Man, Herrup, Karl, Li, Jiali
Published in The FASEB journal (01.12.2020)
Published in The FASEB journal (01.12.2020)
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Journal Article
ATM is activated by ATP depletion and modulates mitochondrial function through NRF1
Chow, Hei-Man, Cheng, Aifang, Song, Xuan, Swerdel, Mavis R, Hart, Ronald P, Herrup, Karl
Published in The Journal of cell biology (04.03.2019)
Published in The Journal of cell biology (04.03.2019)
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Journal Article
Enhanced insulin‐regulated phagocytic activities support extreme health span and longevity in multiple populations
Wu, Deng, Bi, Xiaoman, Li, Peihu, Xu, Dahua, Qiu, Jianmin, Li, Kongning, Zheng, Shaojiang, Chow, Kim Hei‐Man
Published in Aging cell (01.05.2023)
Published in Aging cell (01.05.2023)
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Journal Article
ATM loss disrupts the autophagy-lysosomal pathway
Cheng, Aifang, Tse, Kai-Hei, Chow, Hei-Man, Gan, Yunqiao, Song, Xuan, Ma, Fulin, Qian, Yi Xuan Yvonne, She, Weiyi, Herrup, Karl
Published in Autophagy (03.08.2021)
Published in Autophagy (03.08.2021)
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Journal Article
Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons
Sun, Jacquelyne Ka‐Li, Wu, Deng, Wong, Genper Chi‐Ngai, Lau, Tsun‐Ming, Yang, Meigui, Hart, Ronald P., Kwan, Kin‐Ming, Chan, Ho Yin Edwin, Chow, Hei‐Man
Published in Aging cell (01.02.2023)
Published in Aging cell (01.02.2023)
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Journal Article
Cross-talk between DNA damage response and the central carbon metabolic network underlies selective vulnerability of Purkinje neurons in ataxia-telangiectasia
Sun, Jacquelyne Ka-Li, Wong, Genper Chi-Ngai, Chow, Kim Hei-Man
Published in Journal of neurochemistry (01.08.2023)
Published in Journal of neurochemistry (01.08.2023)
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Journal Article
Insulin stimulates atypical protein kinase C‐mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6‐Rac1 signaling
Chau, Dennis Dik‐Long, Li, Wen, Chan, Wai Wa Ray, Sun, Jacquelyne Ka‐Li, Zhai, Yuqi, Chow, Hei‐Man, Lau, Kwok‐Fai
Published in The FASEB journal (01.11.2022)
Published in The FASEB journal (01.11.2022)
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Journal Article
A critical review of ethanol effects on neuronal firing: A metabolic perspective
Popova, Dina, Sun, Jacquelyne, Chow, Hei‐Man, Hart, Ronald P.
Published in Alcohol, clinical & experimental research (01.03.2024)
Published in Alcohol, clinical & experimental research (01.03.2024)
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Journal Article
CDK5 activator protein p25 preferentially binds and activates GSK3β
Chow, Hei-Man, Guo, Dong, Zhou, Jie-Chao, Zhang, Guan-Yun, Li, Hui-Fang, Herrup, Karl, Zhang, Jie
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2014)
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Journal Article
A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities
Peng, Shaohong Isaac, Leong, Lok I, Sun, Jacquelyne Ka-Li, Chen, Zhefan Stephen, Chow, Hei-Man, Chan, Ho Yin Edwin
Published in Molecular therapy. Nucleic acids (13.09.2022)
Published in Molecular therapy. Nucleic acids (13.09.2022)
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Journal Article
Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes
Chow, Hei‐Man, Sun, Jacquelyne Ka‐Li, Hart, Ronald P., Cheng, Kenneth King‐Yip, Hung, Clara H. L., Lau, Tsun‐Ming, Kwan, Kin‐Ming
Published in Advanced science (01.08.2021)
Published in Advanced science (01.08.2021)
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Journal Article
Force-induced tail-autotomy mitochondrial fission and biogenesis of matrix-excluded mitochondrial-derived vesicles for quality control
Liu, Xiaoying, Xu, Linyu, Song, Yutong, Zhao, Zhihao, Li, Xinyu, Wong, Cheuk-Yiu, Chen, Rong, Feng, Jianxiong, Gou, Yitao, Qi, Yajing, Chow, Hei-Man, Yao, Shuhuai, Wang, Yi, Gao, Song, Liu, Xingguo, Duan, Liting
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2024)
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Journal Article
ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations
Cheng, Aifang, Zhao, Teng, Tse, Kai-Hei, Chow, Hei-Man, Cui, Yong, Jiang, Liwen, Du, Shengwang, Loy, Michael M. T., Herrup, Karl
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2018)
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Journal Article
Cyclin-Dependent Kinase 5–Dependent BAG3 Degradation Modulates Synaptic Protein Turnover
Zhou, Jiechao, Chow, Hei-Man, Liu, Yan, Wu, Di, Shi, Meng, Li, Jieyin, Wen, Lei, Gao, Yuehong, Chen, Guimiao, Zhuang, Kai, Lin, Hui, Zhang, Guanyun, Xie, Wenting, Li, Huifang, Leng, Lige, Wang, Mengdan, Zheng, Naizhen, Sun, Hao, Zhao, Yingjun, Zhang, Yunwu, Xue, Maoqiang, Huang, Timothy Y., Bu, Guojun, Xu, Huaxi, Yuan, Zengqiang, Herrup, Karl, Zhang, Jie
Published in Biological psychiatry (1969) (15.04.2020)
Published in Biological psychiatry (1969) (15.04.2020)
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