Phase I Study of ARN-509, a Novel Antiandrogen, in the Treatment of Castration-Resistant Prostate Cancer
RATHKOPF, Dana E, MORRIS, Michael J, FLEISHER, Martin, LARSON, Steven M, SAWYERS, Charles L, SCHER, Howard I, FOX, Josef J, DANILA, Daniel C, SLOVIN, Susan F, HAGER, Jeffrey H, RIX, Peter J, CHOW ANEVAL, Edna, CHEN, Isan, GÖNEN, Mithat
Published in Journal of clinical oncology (01.10.2013)
Published in Journal of clinical oncology (01.10.2013)
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Journal Article
A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509
Joseph, James D, Lu, Nhin, Qian, Jing, Sensintaffar, John, Shao, Gang, Brigham, Dan, Moon, Michael, Maneval, Edna Chow, Chen, Isan, Darimont, Beatrice, Hager, Jeffrey H
Published in Cancer discovery (01.09.2013)
Published in Cancer discovery (01.09.2013)
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Journal Article
Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort
Smith, Matthew R, Antonarakis, Emmanuel S, Ryan, Charles J, Berry, William R, Shore, Neal D, Liu, Glenn, Alumkal, Joshi J, Higano, Celestia S, Chow Maneval, Edna, Bandekar, Rajesh, de Boer, Carla J, Yu, Margaret K, Rathkopf, Dana E
Published in European urology (01.12.2016)
Published in European urology (01.12.2016)
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Journal Article
Phase II Study of Sunitinib Administered in a Continuous Once-Daily Dosing Regimen in Patients With Cytokine-Refractory Metastatic Renal Cell Carcinoma
ESCUDIER, Bernard, ROIGAS, Jan, CHEN, Isan, VOGELZANG, Nicholas J, GILLESSEN, Silke, HARMENBERG, Ulrika, SRINIVAS, Sandhya, MULDER, Sasja F, FOUNTZILAS, George, PESCHEL, Christian, FLODGREN, Per, CHOW MANEVAL, Edna
Published in Journal of clinical oncology (01.09.2009)
Published in Journal of clinical oncology (01.09.2009)
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Journal Article
Randomized, Placebo-Controlled, Phase III Trial of Sunitinib Plus Prednisone Versus Prednisone Alone in Progressive, Metastatic, Castration-Resistant Prostate Cancer
DROR MICHAELSON, M, OUDARD, Stephane, LAESTADIUS, Fredrik, ULLEN, Anders, BAHL, Amit, CASTELLANO, Daniel, GSCHWEND, Juergen, MAURINA, Tristan, CHOW MANEVAL, Edna, WANG, Shaw-Ling, LECHUGA, Maria Jose, PAOLINI, Jolanda, OU, Yen-Chuan, ISAN CHEN, SENGELØV, Lisa, SAAD, Fred, HOUEDE, Nadine, OSTLER, Peter, STENZL, Arnulf, DAUGAARD, Gedske, JONES, Robert
Published in Journal of clinical oncology (10.01.2014)
Published in Journal of clinical oncology (10.01.2014)
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Journal Article
Conference Proceeding
Novel TLE4‐NTRK2 fusion in a ganglioglioma identified by array‐CGH and confirmed by NGS: Potential for a gene targeted therapy
Prabhakaran, Nitya, Guzman, Miguel A., Navalkele, Pournima, Chow‐Maneval, Edna, Batanian, Jacqueline R.
Published in Neuropathology (01.08.2018)
Published in Neuropathology (01.08.2018)
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Journal Article
Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG)
Desai, Ami V, Robinson, Giles W, Gauvain, Karen, Basu, Ellen M, Macy, Margaret E, Maese, Luke, Whipple, Nicholas S, Sabnis, Amit J, Foster, Jennifer H, Shusterman, Suzanne, Yoon, Janet, Weiss, Brian D, Abdelbaki, Mohamed S, Armstrong, Amy E, Cash, Thomas, Pratilas, Christine A, Corradini, Nadège, Marshall, Lynley V, Farid-Kapadia, Mufiza, Chohan, Saibah, Devlin, Clare, Meneses-Lorente, Georgina, Cardenas, Alison, Hutchinson, Katherine E, Bergthold, Guillaume, Caron, Hubert, Chow Maneval, Edna, Gajjar, Amar, Fox, Elizabeth
Published in Neuro-oncology (Charlottesville, Va.) (03.10.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.10.2022)
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Journal Article
Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing on Enzalutamide
Abida, Wassim, Hahn, Andrew W, Shore, Neal, Agarwal, Neeraj, Sieber, Paul, Smith, Matthew R, Dorff, Tanya, Monk, Paul, Rettig, Matthew, Patel, Rupal, Page, Anne, Duff, Maureen, Xu, Rongda, Wang, Jian, Barkund, Shravani, Pankov, Aleksandr, Wang, Amber, Junttila, Melissa R, Multani, Pratik S, Daemen, Anneleen, Chow Maneval, Edna, Logothetis, Christopher J, Morris, Michael J
Published in Clinical cancer research (15.03.2024)
Published in Clinical cancer research (15.03.2024)
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Journal Article
The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 −) advanced/metastatic breast cancer
Bardia, Aditya, Mayer, Ingrid, Winer, Eric, Linden, Hannah M., Ma, Cynthia X., Parker, Barbara A., Bellet, Meritxell, Arteaga, Carlos L., Cheeti, Sravanthi, Gates, Mary, Chang, Ching-Wei, Fredrickson, Jill, Spoerke, Jill M., Moore, Heather M., Giltnane, Jennifer, Friedman, Lori S., Chow Maneval, Edna, Chan, Iris, Jhaveri, Komal
Published in Breast cancer research and treatment (01.01.2023)
Published in Breast cancer research and treatment (01.01.2023)
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Journal Article
Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor
Alvarez-Breckenridge, Christopher, Miller, Julie J., Nayyar, Naema, Gill, Corey M., Kaneb, Andrew, D’Andrea, Megan, Le, Long P., Lee, Jesse, Cheng, Ju, Zheng, Zongli, Butler, William E., Multani, Pratik, Chow Maneval, Edna, Ha Paek, Sun, Toyota, Brian D., Dias-Santagata, Dora, Santagata, Sandro, Romero, Javier, Shaw, Alice T., Farago, Anna F., Yip, Stephen, Cahill, Daniel P., Batchelor, Tracy T., Iafrate, A. John, Brastianos, Priscilla K.
Published in NPJ precision oncology (20.03.2017)
Published in NPJ precision oncology (20.03.2017)
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5-Fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus sunitinib or bevacizumab as first-line treatment for metastatic colorectal cancer: a randomized Phase IIb study
Hecht, J Randolph, Mitchell, Edith P, Yoshino, Takayuki, Welslau, Manfred, Lin, Xun, Chow Maneval, Edna, Paolini, Jolanda, Lechuga, Maria Jose, Kretzschmar, Albrecht
Published in Cancer management and research (01.01.2015)
Published in Cancer management and research (01.01.2015)
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Journal Article
Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy
SALTZ, Leonard B, ROSEN, Lee S, XIN HUANG, DEPRIMO, Samuel E, CHOW-MANEVAL, Edna, CHAO, Richard C, LENZ, Heinz J, MARSHALL, John L, BELT, Robert J, HURWITZ, Herbert L, ECKHARDT, S. Gail, BERGSLAND, Emily K, HALLER, Daniel G, LOCKHART, A. Craig, ROCHA LIMA, Caio M
Published in Journal of clinical oncology (20.10.2007)
Published in Journal of clinical oncology (20.10.2007)
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Journal Article
Radiographic progression by Prostate Cancer Working Group (PCWG)‐2 criteria as an intermediate endpoint for drug development in metastatic castration‐resistant prostate cancer
Sonpavde, Guru, Pond, Gregory R., Armstrong, Andrew J., Galsky, Matthew D., Leopold, Lance, Wood, Brian A., Wang, Shaw‐Ling, Paolini, Jolanda, Chen, Isan, Chow‐Maneval, Edna, Mooney, David J., Lechuga, Mariajose, Smith, Matthew R., Michaelson, M. Dror
Published in BJU international (01.12.2014)
Published in BJU international (01.12.2014)
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Journal Article
Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone
Rathkopf, Dana E, Antonarakis, Emmanuel S, Shore, Neal D, Tutrone, Ronald F, Alumkal, Joshi J, Ryan, Charles J, Saleh, Mansoor, Hauke, Ralph J, Bandekar, Rajesh, Maneval, Edna Chow, de Boer, Carla J, Yu, Margaret K, Scher, Howard I
Published in Clinical cancer research (15.07.2017)
Published in Clinical cancer research (15.07.2017)
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Journal Article
Abstract P015: Biomarker results supporting selection of RP2D from a phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, in combination with enzalutamide in patients with metastatic prostate cancer progressing on enzalutamide
Daemen, Anneleen, Barkund, Shravani, Johnson, Ann, Pankov, Aleksandr, Wang, Amber W., Zhou, Haiying, Multani, Pratik S., Maneval, Edna Chow, Friedman, Lori S., Patel, Rupal
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
Phase 1 Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer Progressing on Enzalutamide
Abida, Wassim, Hahn, Andrew W, Shore, Neal, Agarwal, Neeraj, Sieber, Paul, Smith, Matthew R, Dorff, Tanya, Monk, Paul, Rettig, Matthew, Patel, Rupal, Page, Anne, Duff, Maureen, Xu, Rongda, Wang, Jian, Barkund, Shravani, Pankov, Aleksandr, Wang, Amber, Junttila, Melissa, Multani, Pratik S, Daemen, Anneleen, Maneval, Edna Chow, Logothetis, Christopher J, Morris, Michael J
Published in Clinical cancer research (15.03.2024)
Published in Clinical cancer research (15.03.2024)
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Journal Article
Activity of Entrectinib in a Patient With the First Reported NTRK Fusion in Neuroendocrine Cancer
Sigal, Darren, Tartar, Marie, Xavier, Marin, Bao, Fei, Foley, Patrick, Luo, David, Christiansen, Jason, Hornby, Zachary, Maneval, Edna Chow, Multani, Pratik
Published in Journal of the National Comprehensive Cancer Network (01.11.2017)
Published in Journal of the National Comprehensive Cancer Network (01.11.2017)
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Abstract P041: Initial results from a phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, in combination with enzalutamide in patients with metastatic prostate cancer
Abida, Wassim, Agarwal, Neeraj, Hahn, Andrew W., Shore, Neal, Sieber, Paul, Dorff, Tanya, Rettig, Mathew, Smith, Mathew, Monk, Paul, Xu, Rongda, Johnson, Ann, Daemen, Anneleen, Maneval, Edna Chow, Multani, Pratik S., Patel, Rupal, Morris, Michael J.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Journal Article
TRTH-10. PEDIATRIC PHASE 1/1B STUDY OF ENTRECTINIB IN PATIENTS WITH PRIMARY BRAIN TUMORS, NEUROBLASTOMA, AND NTRK, ROS1, OR ALK FUSIONS
Rangaraju, Sunitha, Li, Gang, Christiansen, Jason, Hornby, Zachary, Multani, Pratik, Esquibel, Vanessa, Maneval, Edna Chow
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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Journal Article
Abstract B28: Overcoming drug resistance to Trk inhibition by rational combination of entrectinib and trametinib: from bench to bedside
Wei, Ge, Maneval, Edna Chow, Esquibel, Vanessa, Berger, Michael F., Haque, Sofia, Patel, Roopal, Walsh, Colin, Hornby, Zachary, Multani, Pratik, Li, Gary
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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