Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases
Pemberton, Travis A, Chen, Mengbin, Harris, Golda G, Chou, Wayne K. W, Duan, Lian, Köksal, Mustafa, Genshaft, Alex S, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (11.04.2017)
Published in Biochemistry (Easton) (11.04.2017)
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Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase
Chen, Mengbin, Chou, Wayne K. W, Toyomasu, Tomonobu, Cane, David E, Christianson, David W
Published in ACS chemical biology (15.04.2016)
Published in ACS chemical biology (15.04.2016)
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Genome Mining in Streptomyces avermitilis: Cloning and Characterization of SAV_76, the Synthase for a New Sesquiterpene, Avermitilol
Chou, Wayne K. W, Fanizza, Immacolata, Uchiyama, Takuma, Komatsu, Mamoru, Ikeda, Haruo, Cane, David E
Published in Journal of the American Chemical Society (07.07.2010)
Published in Journal of the American Chemical Society (07.07.2010)
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Journal Article
Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate
Köksal, Mustafa, Chou, Wayne K. W, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (10.04.2012)
Published in Biochemistry (Easton) (10.04.2012)
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Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes
Blank, Patrick N, Barrow, Golda H, Chou, Wayne K. W, Duan, Lian, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (31.10.2017)
Published in Biochemistry (Easton) (31.10.2017)
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Journal Article
Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase
Li, Ruiqiong, Chou, Wayne K. W, Himmelberger, Julie A, Litwin, Kevin M, Harris, Golda G, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (25.02.2014)
Published in Biochemistry (Easton) (25.02.2014)
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The T296V Mutant of Amorpha-4,11-diene Synthase Is Defective in Allylic Diphosphate Isomerization but Retains the Ability To Cyclize the Intermediate (3R)‑Nerolidyl Diphosphate to Amorpha-4,11-diene
Li, Zhenqiu, Gao, Ruiping, Hao, Qinggang, Zhao, Huifang, Cheng, Longbin, He, Fang, Liu, Li, Liu, Xiuhua, Chou, Wayne K. W, Zhu, Huajie, Cane, David E
Published in Biochemistry (Easton) (06.12.2016)
Published in Biochemistry (Easton) (06.12.2016)
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Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase
Chen, Mengbin, Chou, Wayne K. W, Al-Lami, Naeemah, Faraldos, Juan A, Allemann, Rudolf K, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (24.05.2016)
Published in Biochemistry (Easton) (24.05.2016)
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Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence
Harris, Golda G, Lombardi, Patrick M, Pemberton, Travis A, Matsui, Tsutomu, Weiss, Thomas M, Cole, Kathryn E, Köksal, Mustafa, Murphy, Frank V, Vedula, L. Sangeetha, Chou, Wayne K. W, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (08.12.2015)
Published in Biochemistry (Easton) (08.12.2015)
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Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with Alpha-Alpha Domain Architecture that Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence
Harris, Golda G., Lombardi, Patrick M., Pemberton, Travis A., Matsui, Tsutomu, Weiss, Thomas M., Cole, Kathryn E., Köksal, Mustafa, Murphy, Frank V., Vedula, L. Sangeetha, Chou, Wayne K.W., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (08.12.2015)
Published in Biochemistry (Easton) (08.12.2015)
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Journal Article
Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase
Chen, Mengbin, Chou, Wayne K. W., Al-Lami, Naeemah, Faraldos, Juan A., Allemann, Rudolf K., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (24.05.2016)
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Published in Biochemistry (Easton) (24.05.2016)
Journal Article
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence
Harris, Golda G., Lombardi, Patrick M., Pemberton, Travis A., Matsui, Tsutomu, Weiss, Thomas M., Cole, Kathryn E., Köksal, Mustafa, Murphy, Frank V., Vedula, L. Sangeetha, Chou, Wayne K. W., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (08.12.2015)
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Published in Biochemistry (Easton) (08.12.2015)
Journal Article
Structure of 2-methylisoborneol synthase from Streptomyces coelicolor and implications for the cyclization of a non-canonical C-methylated monoterpenoid substrate
Köksal, Mustafa, Chou, Wayne K. W., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (28.03.2012)
Published in Biochemistry (Easton) (28.03.2012)
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Genome Mining in Streptomyces clavuligerus. Expression and Biochemical Characterization of Two Cryptic Sesquiterpene Cyclases, (−)-δ-Cadinene Synthase and (+)-T-Muurolol Synthase
Hu, Yunfeng, Chou, Wayne K. W., Hopson, Russell, Cane, David E.
Published in Chemistry & biology (28.01.2011)
Published in Chemistry & biology (28.01.2011)
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