TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon E., Vaughan, Spencer W., Lorenzini, Ileana, Liu, Feilin, Sayegh, Melissa, Donlin-Asp, Paul G., Chen, Yu Han, Duong, Duc M., Seyfried, Nicholas T., Powers, Maureen A., Kukar, Thomas, Hales, Chadwick M., Gearing, Marla, Cairns, Nigel J., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa, Zhang, Yong-Jie, Petrucelli, Leonard, Sattler, Rita, Zarnescu, Daniela C., Glass, Jonathan D., Rossoll, Wilfried
Published in Nature neuroscience (01.02.2018)
Published in Nature neuroscience (01.02.2018)
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Journal Article
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS
Coyne, Alyssa N., Lorenzini, Ileana, Chou, Ching-Chieh, Torvund, Meaghan, Rogers, Robert S., Starr, Alexander, Zaepfel, Benjamin L., Levy, Jennifer, Johannesmeyer, Jeffrey, Schwartz, Jacob C., Nishimune, Hiroshi, Zinsmaier, Konrad, Rossoll, Wilfried, Sattler, Rita, Zarnescu, Daniela C.
Published in Cell reports (Cambridge) (03.10.2017)
Published in Cell reports (Cambridge) (03.10.2017)
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Journal Article
The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly
Donlin-Asp, Paul G., Fallini, Claudia, Campos, Jazmin, Chou, Ching-Chieh, Merritt, Megan E., Phan, Han C., Bassell, Gary J., Rossoll, Wilfried
Published in Cell reports (Cambridge) (14.02.2017)
Published in Cell reports (Cambridge) (14.02.2017)
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Journal Article
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
Khalil, Bilal, Chhangani, Deepak, Wren, Melissa C, Smith, Courtney L, Lee, Jannifer H, Li, Xingli, Puttinger, Christian, Tsai, Chih-Wei, Fortin, Gael, Morderer, Dmytro, Gao, Junli, Liu, Feilin, Lim, Chun Kim, Chen, Jingjiao, Chou, Ching-Chieh, Croft, Cara L, Gleixner, Amanda M, Donnelly, Christopher J, Golde, Todd E, Petrucelli, Leonard, Oskarsson, Björn, Dickson, Dennis W, Zhang, Ke, Shorter, James, Yoshimura, Shige H, Barmada, Sami J, Rincon-Limas, Diego E, Rossoll, Wilfried
Published in Molecular neurodegeneration (08.12.2022)
Published in Molecular neurodegeneration (08.12.2022)
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Journal Article
Cycling Regimen Induces Spinal Circuitry Plasticity and Improves Leg Muscle Coordination in Individuals With Spinocerebellar Ataxia
Chang, Ya-Ju, PhD, Chou, Ching-Chieh, MS, Huang, Wan-Ting, MS, Lu, Chin-Song, MD, Wong, Alice M., MD, Hsu, Miao-Ju, PhD
Published in Archives of physical medicine and rehabilitation (01.06.2015)
Published in Archives of physical medicine and rehabilitation (01.06.2015)
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Journal Article
Effects of Botulinum Toxin Landmark-Guided Intra-articular Injection in Subjects With Knee Osteoarthritis
Hsieh, Lin-Fen, MD, Wu, Chia-Wei, MD, Chou, Ching-Chieh, PT, MS, Yang, Sai-Wei, PhD, Wu, Shih-Hui, MD, Lin, Yi-Jia, MS, ATC, Hsu, Wei-Chun, PhD, PT
Published in PM & R (01.12.2016)
Published in PM & R (01.12.2016)
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Journal Article
Increases of quadriceps inter-muscular cross-correlation and coherence during exhausting stepping exercise
Chang, Ya-Ju, Chou, Ching-Chieh, Chan, Hsiao-Lung, Hsu, Miao-Ju, Yeh, Ming-Yuh, Fang, Chia-Ying, Chuang, Yu-Fen, Wei, Shun-Hwa, Lien, Hen-Yu
Published in Sensors (Basel, Switzerland) (01.12.2012)
Published in Sensors (Basel, Switzerland) (01.12.2012)
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Journal Article
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration
Vest, Ryan T, Chou, Ching-Chieh, Zhang, Hui, Haney, Michael S, Li, Lulin, Laqtom, Nouf N, Chang, Betty, Shuken, Steven, Nguyen, Andy, Yerra, Lakshmi, Yang, Andrew C, Green, Carol, Tanga, Mary, Abu-Remaileh, Monther, Bassik, Michael C, Frydman, Judith, Luo, Jian, Wyss-Coray, Tony
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.2022)
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Journal Article
PABPN1 suppresses TDP-43 toxicity in ALS disease models
Chou, Ching-Chieh, Alexeeva, Olga M, Yamada, Shizuka, Pribadi, Amy, Zhang, Yi, Mo, Bi, Williams, Kathryn R, Zarnescu, Daniela C, Rossoll, Wilfried
Published in Human molecular genetics (15.09.2015)
Published in Human molecular genetics (15.09.2015)
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Journal Article
Anatomical and functional evidence for trace amines as unique modulators of locomotor function in the mammalian spinal cord
Gozal, Elizabeth A, O'Neill, Brannan E, Sawchuk, Michael A, Zhu, Hong, Halder, Mallika, Chou, Ching-Chieh, Hochman, Shawn
Published in Frontiers in neural circuits (07.11.2014)
Published in Frontiers in neural circuits (07.11.2014)
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Journal Article
TDP-43 PATHOLOGY DISRUPTS NUCLEAR PORE COMPLEXES AND NUCLEOCYTOPLASMIC TRANSPORT IN ALS/FTD
Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon, Seyfried, Nicholas T., Powers, Maureen, Kukar, Thomas, Boylan, Kevin, Dickson, Dennis W., Rademakers, Rosa, Zarnescu, Daniela, Glass, Jonathan, Rossoll, Wilfried
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article
Robot-Assisted Passive Exercise for Ankle Hypertonia in Individuals with Chronic Spinal Cord Injury
Fang, Chia-Ying, Hsu, Miao-Ju, Chen, Chih-Chung, Cheng, Hsin-Yi Kathy, Chou, Ching-Chieh, Chang, Ya-Ju
Published in Journal of medical and biological engineering (01.08.2015)
Published in Journal of medical and biological engineering (01.08.2015)
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Journal Article
Exploring lysosomal defects and rescue strategies for Alzheimer’s disease using human transdifferentiated neurons
Chou, Ching‐Chieh, Vest, Ryan, Shibuya, Yohei, Prado, Miguel A, Wilson‐Grady, Joshua, Greicius, Michael D, Finley, Daniel, Wernig, Marius, Wyss‐Coray, Tony, Frydman, Judith
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes
Frydman, Judith, Chou, Ching-Chieh, Vest, Ryan, Prado, Miguel, Wilson-Grady, Joshua, Paulo, Joao, Shibuya, Yohei, Losada, Patricia Moran, Lee, Ting-Ting, Luo, Jian, Gygi, Steven, Kelly, Jeffrey, Finley, Daniel, Wernig, Marius, Wyss-Coray, Tony
Published in Research square (30.05.2024)
Published in Research square (30.05.2024)
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Journal Article
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons
Chou, Ching-Chieh, Vest, Ryan, Prado, Miguel A, Wilson-Grady, Joshua, Paulo, Joao A, Shibuya, Yohei, Moran-Losada, Patricia, Lee, Ting-Ting, Luo, Jian, Gygi, Steven P, Kelly, Jeffery W, Finley, Daniel, Wernig, Marius, Wyss-Coray, Tony, Frydman, Judith
Published in bioRxiv : the preprint server for biology (27.03.2023)
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Published in bioRxiv : the preprint server for biology (27.03.2023)
Journal Article
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway
Elsasser, Suzanne, Elia, Lisa P, Morimoto, Richard I, Powers, Evan T, Finley, Daniel, Costa, Beatrice, Budron, Maher, Tokuno, Zachary, Wang, Shijie, Iyer, Rajshri G, Barth, Bianca, Mockler, Eric, Finkbeiner, Steve, Gestwicki, Jason E, Richardson, Reese A K, Stoeger, Thomas, Tan, Ee Phie, Xiao, Qiang, Cole, Christian M, Massey, Lynée A, Garza, Dan, Kelly, Jeffery W, Rainbolt, T Kelly, Chou, Ching-Chieh, Masto, Vincent B, Frydman, Judith, Nixon, Ralph A
Published in bioRxiv (24.03.2023)
Published in bioRxiv (24.03.2023)
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Journal Article
A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems
The Proteostasis Consortium, Elsasser, Suzanne, Finley, Daniel, Mockler, Eric, Lima, Leandro, Finkbeiner, Steven, Gestwicki, Jason E, Stoeger, Thomas E, Cao, Kedi, Garza, Dan, Kelly, Jeffery W, Collier, Miranda, T Kelly Rainbolt, Taguwa, Shuhei, Chou, Ching-Chieh, Aviner, Ranen, Barbosa, Natalia, Moralez-Polanco, Fabian, Masto, Vincent B, Frydman, Judith, Elia, Lisa P, Morimoto, Richard I, Powers, Evan T
Published in bioRxiv (02.09.2022)
Published in bioRxiv (02.09.2022)
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mTOR inhibitor-independent Autophagy Activator Ameliorates Cellular Tauopathy and Prionopathy Neurodegeneration Phenotypes
Yoon, Leonard, Botham, Rachel C, Verhelle, Adriaan, Cole, Christian, Tan, Ee Phie, Wu, Yin, Sanz-Martinez, Pablo, Xu, Jin, Cuoco, Caroline A, Chou, Ching Chieh, Labra, Sergio, Elia, Lisa P, Massey, Lynee A, Lee, Kyunga, Xiao, Qiang, Kline, Gabriel M, Ta, Amina, Ardejani, Maziar S, Cano-Franco, Sara, Lyang, Nora J, Hou, William C, Yu, Anan, Fox, Susan, Ko, Yeonjin, Chen, Wenbo, Wulkop-Gil, Cristian, Ibrahim, Lara H, Starr, Jiang, Meneses, Alina, Nelson, Luke T, Peng, Hongfan, Lipton, Stuart A, Bollong, Michael J, Hansen, Malene, Morimoto, Richard I, Finley, Daniel, Petrassi, H Michael, R Luke Wiseman, Powers, Evan T, Finkbeiner, Steven, Garza, Dan, Prado, Miguel A, Dikic, Ivan, Frydman, Judith, Johnson, Kristen A, Silva, M Catarina, Haggarty, Stephen J, Stolz, Alexandra, Encalada, Sandra E, Kelly, Jeffery W
Published in bioRxiv (30.09.2022)
Published in bioRxiv (30.09.2022)
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