Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
Teng, Jin-Feng, Mei, Qi-Bing, Zhou, Xiao-Gang, Tang, Yong, Xiong, Rui, Qiu, Wen-Qiao, Pan, Rong, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Long, Han-An, Xiao, Xiu-Li, Zhang, Feng, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo
Published in Cancers (13.01.2020)
Published in Cancers (13.01.2020)
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Lychee seed polyphenol protects the blood–brain barrier through inhibiting Aβ(25–35)‐induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1‐mediated autophagy in bEnd.3 cells and APP/PS1 mice
Xiong, Rui, Zhou, Xiao‐Gang, Tang, Yong, Wu, Jian‐Ming, Sun, Yue‐Shan, Teng, Jin‐Feng, Pan, Rong, Law, Betty Yuen‐Kwan, Zhao, Ya, Qiu, Wen‐Qiao, Wang, Xiu‐Ling, Liu, Sha, Wang, Yi‐Ling, Yu, Lu, Yu, Chong‐Lin, Mei, Qi‐Bing, Qin, Da‐Lian, Wu, An‐Guo
Published in Phytotherapy research (01.02.2021)
Published in Phytotherapy research (01.02.2021)
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Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer
Teng, Jin-Feng, Qin, Da-Lian, Mei, Qi-Bing, Qiu, Wen-Qiao, Pan, Rong, Xiong, Rui, Zhao, Ya, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Tang, Yong, Yu, Chong-Lin, Zhang, Feng, Wu, Jian-Ming, Wu, An-Guo
Published in Pharmacological research (01.09.2019)
Published in Pharmacological research (01.09.2019)
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Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction
Qiu, Wen-Qiao, Pan, Rong, Tang, Yong, Zhou, Xiao-Gang, Wu, Jian-Ming, Yu, Lu, Law, Betty Yuen-Kwan, Ai, Wei, Yu, Chong-Lin, Qin, Da-Lian, Wu, An-Guo
Published in Biomedicine & pharmacotherapy (01.10.2020)
Published in Biomedicine & pharmacotherapy (01.10.2020)
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The Protective Effects of Reineckia carnea Ether Fraction against Alzheimer’s Disease Pathology: An Exploration in Caenorhabditis elegans Models
Fu, Hai-Jun, Zhou, Xing-Yue, Li, Ya-Ping, Chen, Xue, He, Yan-Ni, Qin, Da-Lian, Yu, Lu, Yu, Chong-Lin, Wu, Jian-Ming, Wu, An-Guo, Zhou, Xiao-Gang
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
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Ameliorative effect of Luffa cylindrica fruits on Caenorhabditis elegans and cellular models of Alzheimer's disease-related pathology via autophagy induction
Long, Tao, Chen, Xue, Qin, Da-Lian, Zhu, Yun-Fei, Zhou, Yu-Jia, He, Yan-Ni, Fu, Hai-Jun, Tang, Yong, Yu, Lu, Huang, Fei-Hong, Wang, Long, Yu, Chong-Lin, Law, Betty Yuen-Kwan, Wu, Jian-Ming, Wu, An-Guo, Zhou, Xiao-Gang
Published in Phytotherapy research (01.10.2023)
Published in Phytotherapy research (01.10.2023)
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Dietary Plant Polyphenols as the Potential Drugs in Neurodegenerative Diseases: Current Evidence, Advances, and Opportunities
Yan, Lu, Guo, Min-Song, Zhang, Yue, Yu, Lu, Wu, Jian-Ming, Tang, Yong, Ai, Wei, Zhu, Feng-Dan, Law, Betty Yuen-Kwan, Chen, Qi, Yu, Chong-Lin, Wong, Vincent Kam-Wai, Li, Hua, Li, Mao, Zhou, Xiao-Gang, Qin, Da-Lian, Wu, An-Guo
Published in Oxidative medicine and cellular longevity (2022)
Published in Oxidative medicine and cellular longevity (2022)
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Polyphenols Derived from Lychee Seed Suppress Aβ (1-42)-Induced Neuroinflammation
Tang, Yong, Xiong, Rui, Wu, An-Guo, Yu, Chong-Lin, Zhao, Ya, Qiu, Wen-Qiao, Wang, Xiu-Ling, Teng, Jin-Feng, Liu, Jian, Chen, Hai-Xia, Wu, Jian-Ming, Qin, Da-Lian
Published in International journal of molecular sciences (20.07.2018)
Published in International journal of molecular sciences (20.07.2018)
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The Therapeutic Potential of Plant Polysaccharides in Metabolic Diseases
Wang, Xiao-Fang, Chen, Xue, Tang, Yong, Wu, Jian-Ming, Qin, Da-Lian, Yu, Lu, Yu, Chong-Lin, Zhou, Xiao-Gang, Wu, An-Guo
Published in Pharmaceuticals (Basel, Switzerland) (27.10.2022)
Published in Pharmaceuticals (Basel, Switzerland) (27.10.2022)
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Ferulic Acid Exerts Neuroprotective Effects via Autophagy Induction in C. elegans and Cellular Models of Parkinson’s Disease
Long, Tao, Wu, Qian, Wei, Jing, Tang, Yong, He, Yan-Ni, He, Chang-Long, Chen, Xue, Yu, Lu, Yu, Chong-Lin, Law, Betty Yuen-Kwan, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo, Zhou, Xiao-Gang
Published in Oxidative medicine and cellular longevity (2022)
Published in Oxidative medicine and cellular longevity (2022)
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Carpesii fructus extract exhibits neuroprotective effects in cellular and Caenorhabditis elegans models of Parkinson's disease
Zhu, Feng‐Dan, Wang, Bin‐Ding, Qin, Da‐Lian, Su, Xiao‐Hui, Yu, Lu, Wu, Jian‐Ming, Law, Betty Yuen‐Kwan, Guo, Min‐Song, Yu, Chong‐Lin, Zhou, Xiao‐Gang, Wu, An‐Guo
Published in CNS neuroscience & therapeutics (01.04.2024)
Published in CNS neuroscience & therapeutics (01.04.2024)
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Protective effects of Radix Stellariae extract against Alzheimer's disease via autophagy activation in Caenorhabditis elegans and cellular models
Long, Tao, Chen, Xue, Zhang, Yue, Zhou, Yu-Jia, He, Yan-Ni, Zhu, Yun-Fei, Fu, Hai-Jun, Yu, Lu, Yu, Chong-Lin, Law, Betty Yuen-Kwan, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo, Zhou, Xiao-Gang
Published in Biomedicine & pharmacotherapy (01.09.2023)
Published in Biomedicine & pharmacotherapy (01.09.2023)
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Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice
Xiang, Xiao-Hong, Wei, Jing, Wang, Xiao-Fang, Xu, Qin, Yu, Chong-Lin, He, Chang-Long, Long, Tao, Guo, Ming-Song, Chen, Xue, Zhou, Xiao-Gang, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo, Tang, Yong, Lv, Hong-Bin
Published in Biomedicine & pharmacotherapy (01.11.2023)
Published in Biomedicine & pharmacotherapy (01.11.2023)
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Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals
Wu, An-Guo, Yong, Yuan-Yuan, Pan, Yi-Ru, Zhang, Li, Wu, Jian-Ming, Zhang, Yue, Tang, Yong, Wei, Jing, Yu, Lu, Law, Betty Yuen-Kwan, Yu, Chong-Lin, Liu, Jian, Lan, Cai, Xu, Ru-Xiang, Zhou, Xiao-Gang, Qin, Da-Lian
Published in Oxidative medicine and cellular longevity (2022)
Published in Oxidative medicine and cellular longevity (2022)
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Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease
Qiu, Wen‐Qiao, Yu, Lu, He, Chang‐Long, Wu, Jian‐Ming, Law, Betty Yuen‐Kwan, Yu, Chong‐Lin, Qin, Da‐Lian, Zhou, Xiao‐Gang, Wu, An‐Guo
Published in Clinical and translational medicine (01.09.2023)
Published in Clinical and translational medicine (01.09.2023)
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Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease
Zhou, Xiao-Gang, Qiu, Wen-Qiao, Yu, Lu, Pan, Rong, Teng, Jin-Feng, Sang, Zhi-Pei, Law, Betty Yuen-Kwan, Zhao, Ya, Zhang, Li, Yan, Lu, Tang, Yong, Sun, Xiao-Lei, Wong, Vincent Kam Wai, Yu, Chong-Lin, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo
Published in Inflammation and Regeneration (03.08.2022)
Published in Inflammation and Regeneration (03.08.2022)
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Targeting autophagy as a therapeutic strategy for identification of liganans from Peristrophe japonica in Parkinson's disease
Wu, An-Guo, Pan, Rong, Law, Betty Yuen-Kwan, Qiu, Wen-Qiao, Wu, Jian-Ming, He, Chang-Long, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Zhou, Xiao-Gang, Qin, Da-Lian
Published in Signal transduction and targeted therapy (17.02.2021)
Published in Signal transduction and targeted therapy (17.02.2021)
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Lychee seed polyphenol protects blood-retinal barrier by increasing tight joint proteins and inhibiting the activation of TLR4/MYD88/NF-κB-mediated NLRP3 inflammasome
Wei, Jing, Xiang, Xiao-Hong, Tang, Yong, Qin, Da-Lian, Wu, Jian-Ming, Yu, Chong-Lin, Qiu, Wen-Qiao, Wu, An-Guo, Lv, Hong-Bin
Published in Food and agricultural immunology (01.01.2021)
Published in Food and agricultural immunology (01.01.2021)
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Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases
Wu, An-Guo, Zhou, Xiao-Gang, Qiao, Gan, Yu, Lu, Tang, Yong, Yan, Lu, Qiu, Wen-Qiao, Pan, Rong, Yu, Chong-Lin, Law, Betty Yuen-Kwan, Qin, Da-Lian, Wu, Jian-Ming
Published in Ageing research reviews (01.01.2021)
Published in Ageing research reviews (01.01.2021)
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Polyphenols isolated from lychee seed inhibit Alzheimer's disease-associated Tau through improving insulin resistance via the IRS-1/PI3K/Akt/GSK-3β pathway
Xiong, Rui, Wang, Xiu-Ling, Wu, Jian-Ming, Tang, Yong, Qiu, Wen-Qiao, Shen, Xin, Teng, Jin-Feng, Pan, Rong, Zhao, Ya, Yu, Lu, Liu, Jian, Chen, Hai-Xia, Qin, Da-Lian, Yu, Chong-Lin, Wu, An-Guo
Published in Journal of ethnopharmacology (06.04.2020)
Published in Journal of ethnopharmacology (06.04.2020)
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