IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Matsunaga, Atsuko, Fang, Xuexiu, Pacholczyk, Rafal, Zhou, Gang, Cowell, John K, Hu, Tianxiang
Published in Molecular cancer (14.12.2021)
Published in Molecular cancer (14.12.2021)
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Journal Article
miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes
Hu, Tianxiang, Chong, Yating, Lu, Sumin, Wang, Rebecca, Qin, Haiyan, Silva, Jeane, Kitamura, Eiko, Chang, Chang-Sheng, Hawthorn, LesleyAnn, Cowell, John K
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
RHOA-regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia
Zhang, Hualei, Cai, Baohuan, Liu, Yun, Chong, Yating, Matsunaga, Atsuko, Mori, Stephanie Fay, Fang, Xuexiu, Kitamura, Eiko, Chang, Chang-Sheng, Wang, Ping, Cowell, John K, Hu, Tianxiang
Published in Haematologica (Roma) (01.01.2023)
Published in Haematologica (Roma) (01.01.2023)
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Journal Article
Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome
Hu, Tianxiang, Chong, Yating, Lu, Sumin, McGuinness, Meaghan, Williams, David A, Cowell, John K
Published in Haematologica (Roma) (01.02.2020)
Published in Haematologica (Roma) (01.02.2020)
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Journal Article
A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML
Cai, Baohuan, Liu, Yun, Chong, Yating, Mori, Stephanie Fay, Matsunaga, Atsuko, Zhang, Hualei, Fang, Xuexiu, Chang, Chang-Sheng, Cowell, John K, Hu, Tianxiang
Published in Molecular cancer (29.07.2022)
Published in Molecular cancer (29.07.2022)
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Journal Article
Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome
Liu, Yun, Cai, Baohuan, Chong, Yating, Zhang, Hualei, Kemp, Chesley-Anne, Lu, Sumin, Chang, Chang-Sheng, Ren, Mingqiang, Cowell, John K., Hu, Tianxiang
Published in Cell death & disease (20.10.2020)
Published in Cell death & disease (20.10.2020)
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Journal Article
Effects of the coadministration of Huatuo Zaizao pills and aspirin on hemorrheology and blood coagulation in rabbits
QU, SHUJUN, WANG, TIAN, ZHANG, JIANQIAO, SUN, XUE, YU, PENGFEI, KONG, LIANG, CHONG, YATING, QIU, XIAOLEI, FU, FENGHUA
Published in Biomedical reports (01.05.2013)
Published in Biomedical reports (01.05.2013)
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Journal Article
DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1–driven leukemogenesis
Hu, Tianxiang, Chong, Yating, Cai, Baohuan, Liu, Yun, Lu, Sumin, Cowell, John K.
Published in The Journal of biological chemistry (29.11.2019)
Published in The Journal of biological chemistry (29.11.2019)
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Journal Article
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome
Hu, Tianxiang, Wu, Qing, Chong, Yating, Qin, Haiyan, Poole, Candace J., van Riggelen, Jan, Ren, Mingqiang, Cowell, John K.
Published in Leukemia (01.11.2018)
Published in Leukemia (01.11.2018)
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Journal Article
The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase
Hu, Tianxiang, Chong, Yating, Qin, Haiyan, Kitamura, Eiko, Chang, Chang-Sheng, Silva, Jeane, Ren, Mingqiang, Cowell, John K
Published in Oncogene (01.04.2018)
Published in Oncogene (01.04.2018)
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Journal Article
Poster: MPN-053: Tumor-Intrinsic IRAK1-Dependent Inflammation Signaling Induces MDSC to Establish Immune Evasion in FGFR1-Driven Hematological Malignancies
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhou, Gang, Cowell, John, Hu, Tianxiang
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
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Journal Article
MPN-053: Tumor-Intrinsic IRAKI-Dependent Inflammation Signaling Induces MDSC to Establish Immune Evasion in FGFRI-Driven Hematological Malignancies
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhou, Gang, Cowell, John, Hu, Tianxiang
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
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Journal Article
Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
Chong, Yating, Liu, Yun, Lu, Sumin, Cai, Baohuan, Qin, Haiyan, Chang, Chang‐Sheng, Ren, Mingqiang, Cowell, John K., Hu, Tianxiang
Published in International journal of cancer (15.04.2020)
Published in International journal of cancer (15.04.2020)
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Journal Article
AML-060 A Truncated Nucleus Isoform of FGFR1 Drives the Transformation of Leukemia Stem Cells in Leukemogenesis
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Mori, Stephanie, Matsunaga, Atsuko, Fang, Xuexiu, Cowell, John, Hu, Tianxiang
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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Journal Article
Poster: AML-060 A Truncated Nucleus Isoform of FGFR1 Drives the Transformation of Leukemia Stem Cells in Leukemogenesis
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Mori, Stephanie, Matsunaga, Atsuko, Fang, Xuexiu, Cowell, John, Hu, Tianxiang
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
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Journal Article
Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice
Hu, Tianxiang, Chong, Yating, Lu, Sumin, Qin, Haiyan, Ren, Mingqiang, Savage, Natasha M, Chang, Chang-Sheng, Cowell, John K
Published in Cancer research (Chicago, Ill.) (01.01.2019)
Published in Cancer research (Chicago, Ill.) (01.01.2019)
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Journal Article
IRAK1-regulated IFN-[gamma] signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies
Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Matsunaga, Atsuko, Fang, Xuexiu, Pacholczyk, Rafal, Zhou, Gang, Cowell, John K, Hu, Tianxiang
Published in Molecular cancer (14.12.2021)
Published in Molecular cancer (14.12.2021)
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Journal Article
MicroRNA 339 promotes development of Stem Cell Leukemia/Lymphoma syndrome via downregulation of the BCL2L11 and BAX pro-apoptotic genes
Hu, Tianxiang, Chong, Yating, Lu, Sumin, Wang, Rebecca, Qin, Haiyan, Silva, Jeane, Kitamura, Eiko, Chang, Chang-Sheng, Hawthorn, LesleyAnn, Cowell, John K
Published in Cancer research (Chicago, Ill.) (07.05.2018)
Published in Cancer research (Chicago, Ill.) (07.05.2018)
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Journal Article