Versatile strategy for controlling the specificity and activity of engineered T cells
Ma, Jennifer S. Y., Kim, Ji Young, Kazane, Stephanie A., Choi, Sei-hyun, Yun, Hwa Young, Kim, Min Soo, Rodgers, David T., Pugh, Holly M., Singer, Oded, Sun, Sophie B., Fonslow, Bryan R., Kochenderfer, James N., Wright, Timothy M., Schultz, Peter G., Young, Travis S., Kim, Chan Hyuk, Cao, Yu
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.01.2016)
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Journal Article
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer
Cao, Yu, Rodgers, David T., Du, Juanjuan, Ahmad, Insha, Hampton, Eric N., Ma, Jennifer S. Y., Mazagova, Magdalena, Choi, Sei-hyun, Yun, Hwa Young, Xiao, Han, Yang, Pengyu, Luo, Xiaozhou, Lim, Reyna K. V., Pugh, Holly M., Wang, Feng, Kazane, Stephanie A., Wright, Timothy M., Kim, Chan Hyuk, Schultz, Peter G., Young, Travis S.
Published in Angewandte Chemie (International ed.) (20.06.2016)
Published in Angewandte Chemie (International ed.) (20.06.2016)
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Journal Article
Exploring the potential impact of an expanded genetic code on protein function
Xiao, Han, Nasertorabi, Fariborz, Choi, Sei-hyun, Han, Gye Won, Reed, Sean A., Stevens, Raymond C., Schultz, Peter G.
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (02.06.2015)
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Journal Article
Chemoenzymatic Synthesis of Spinosyn A
Kim, Hak Joong, Choi, Sei-hyun, Jeon, Byung-sun, Kim, Namho, Pongdee, Rongson, Wu, Qingquan, Liu, Hung-wen
Published in Angewandte Chemie (International ed.) (01.12.2014)
Published in Angewandte Chemie (International ed.) (01.12.2014)
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Journal Article
Investigation of the mechanism of the SpnF-catalyzed [4+2]-cycloaddition reaction in the biosynthesis of spinosyn A
Jeon, Byung-sun, Ruszczycky, Mark W., Russell, William K., Lin, Geng-Min, Kim, Namho, Choi, Sei-hyun, Wang, Shao-An, Liu, Yung-nan, Patrick, John W., Russell, David H., Liu, Hung-wen
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
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Journal Article
Mechanistic Studies of the Radical S-Adenosylmethionine Enzyme DesII with TDP-D-Fucose
Ko, Yeonjin, Ruszczycky, Mark W., Choi, Sei-Hyun, Liu, Hung-wen
Published in Angewandte Chemie (International ed.) (12.01.2015)
Published in Angewandte Chemie (International ed.) (12.01.2015)
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Journal Article
Enhancing Thermostability and Organic Solvent Tolerance of ω-Transaminase through Global Incorporation of Fluorotyrosine
Deepankumar, Kanagavel, Shon, Minsu, Nadarajan, Saravanan Prabhu, Shin, Giyoung, Mathew, Sam, Ayyadurai, Niraikulam, Kim, Byung-Gee, Choi, Sei-Hyun, Lee, Sang-Hyeup, Yun, Hyungdon
Published in Advanced synthesis & catalysis (24.03.2014)
Published in Advanced synthesis & catalysis (24.03.2014)
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Journal Article
Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A
Kim, Hak Joong, Ruszczycky, Mark W., Choi, Sei-hyun, Liu, Yung-nan, Liu, Hung-wen
Published in Nature (London) (05.05.2011)
Published in Nature (London) (05.05.2011)
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Journal Article
Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation
Jeon, Byung-sun, Huang, Teng-Yi, Ruszczycky, Mark W., Choi, Sei-hyun, Kim, Namho, Franklin, Joseph Livy, Hung, Shang-Cheng, Liu, Hung-wen
Published in Tetrahedron (01.01.2022)
Published in Tetrahedron (01.01.2022)
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Journal Article
Evidence for an Enzyme-Catalyzed Rauhut–Currier Reaction during the Biosynthesis of Spinosyn A
Choi, Sei-hyun, Jeon, Byungsun, Kim, Namho, Wu, Hsin-Hui, Ko, Tzu-Ping, Ruszczycky, Mark W, Isiorho, Eta A, Liu, Yung-nan, Keatinge-Clay, Adrian T, Tsai, Ming-Daw, Liu, Hung-wen
Published in Journal of the American Chemical Society (08.12.2021)
Published in Journal of the American Chemical Society (08.12.2021)
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Journal Article
An Anti‑B Cell Maturation Antigen Bispecific Antibody for Multiple Myeloma
Ramadoss, Nitya S, Schulman, Andrew D, Choi, Sei-hyun, Rodgers, David T, Kazane, Stephanie A, Kim, Chan Hyuk, Lawson, Brian R, Young, Travis S
Published in Journal of the American Chemical Society (29.04.2015)
Published in Journal of the American Chemical Society (29.04.2015)
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Journal Article
Bispecific small molecule–antibody conjugate targeting prostate cancer
Kim, Chan Hyuk, Axup, Jun Y., Lawson, Brian R., Yun, Hwayoung, Tardif, Virginie, Choi, Sei Hyun, Zhou, Quan, Dubrovska, Anna, Biroc, Sandra L., Marsden, Robin, Pinstaff, Jason, Smider, Vaughn V., Schultz, Peter G.
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
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Journal Article
Switchable CAR-T Cells Outperformed Traditional Antibody-Redirected Therapeutics Targeting Breast Cancers
Cao, Yu J, Wang, Xuechun, Wang, Zhidong, Zhao, Lijun, Li, Shuhong, Zhang, Zhuxia, Wei, Xiaoyi, Yun, Hwayoung, Choi, Sei-Hyun, Liu, Zhong, Zhao, Lili, Kazane, Stephanie A
Published in ACS synthetic biology (21.05.2021)
Published in ACS synthetic biology (21.05.2021)
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Journal Article
Characterization and Mechanistic Studies of DesII: A Radical S-Adenosyl-l-methionine Enzyme Involved in the Biosynthesis of TDP-d-Desosamine
Szu, Ping-Hui, Ruszczycky, Mark W, Choi, Sei-hyun, Yan, Feng, Liu, Hung-wen
Published in Journal of the American Chemical Society (07.10.2009)
Published in Journal of the American Chemical Society (07.10.2009)
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Journal Article
Analysis of UDP‑d‑Apiose/UDP‑d‑Xylose Synthase-Catalyzed Conversion of UDP‑d‑Apiose Phosphonate to UDP‑d‑Xylose Phosphonate: Implications for a Retroaldol–Aldol Mechanism
Choi, Sei-hyun, Mansoorabadi, Steven O, Liu, Yung-nan, Chien, Tun-Cheng, Liu, Hung-wen
Published in Journal of the American Chemical Society (29.08.2012)
Published in Journal of the American Chemical Society (29.08.2012)
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Journal Article
A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand
Lee, Sung Chang, Ma, Jennifer S Y, Kim, Min Soo, Laborda, Eduardo, Choi, Sei-Hyun, Hampton, Eric N, Yun, Hwayoung, Nunez, Vanessa, Muldong, Michelle T, Wu, Christina N, Ma, Wenxue, Kulidjian, Anna A, Kane, Christopher J, Klyushnichenko, Vadim, Woods, Ashley K, Joseph, Sean B, Petrassi, Mike, Wisler, John, Li, Jing, Jamieson, Christina A M, Schultz, Peter G, Kim, Chan Hyuk, Young, Travis S
Published in Science advances (01.08.2021)
Published in Science advances (01.08.2021)
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