Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
Liu, Fei, Lagares, David, Choi, Kyoung Moo, Stopfer, Lauren, Marinković, Aleksandar, Vrbanac, Vladimir, Probst, Clemens K, Hiemer, Samantha E, Sisson, Thomas H, Horowitz, Jeffrey C, Rosas, Ivan O, Fredenburgh, Laura E, Feghali-Bostwick, Carol, Varelas, Xaralabos, Tager, Andrew M, Tschumperlin, Daniel J
Published in American journal of physiology. Lung cellular and molecular physiology (15.02.2015)
Published in American journal of physiology. Lung cellular and molecular physiology (15.02.2015)
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Journal Article
Determination of gastric emptying in nonobese diabetic mice
Choi, Kyoung Moo, Zhu, Jin, Stoltz, Gary J, Vernino, Steven, Camilleri, Michael, Szurszewski, Joseph H, Gibbons, Simon J, Farrugia, Gianrico
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2007)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2007)
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Journal Article
TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression
Jorgenson, Amy J, Choi, Kyoung Moo, Sicard, Delphine, Smith, Karry M J, Hiemer, Samantha E, Varelas, Xaralabos, Tschumperlin, Daniel J
Published in American Journal of Physiology: Cell Physiology (01.03.2017)
Published in American Journal of Physiology: Cell Physiology (01.03.2017)
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Journal Article
Vascular dysfunction in aged mice contributes to persistent lung fibrosis
Caporarello, Nunzia, Meridew, Jeffrey A., Aravamudhan, Aja, Jones, Dakota L., Austin, Susan A., Pham, Tho X., Haak, Andrew J., Moo Choi, Kyoung, Tan, Qi, Haresi, Adil, Huang, Steven K., Katusic, Zvonimir S., Tschumperlin, Daniel J., Ligresti, Giovanni
Published in Aging cell (01.08.2020)
Published in Aging cell (01.08.2020)
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Journal Article
GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
Choi, Kyoung Moo, Haak, Andrew J., Diaz Espinosa, Ana M., Cummins, Katherine A., Link, Patrick A., Aravamudhan, Aja, Wood, David K., Tschumperlin, Daniel J.
Published in Journal of cellular physiology (01.11.2021)
Published in Journal of cellular physiology (01.11.2021)
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Journal Article
Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis
Choi, Kyoung Moo, Gibbons, Simon J, Nguyen, Tien V, Stoltz, Gary J, Lurken, Matthew S, Ordog, Tamas, Szurszewski, Joseph H, Farrugia, Gianrico
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2008)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2008)
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Journal Article
Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying
Hayashi, Yujiro, Toyomasu, Yoshitaka, Saravanaperumal, Siva Arumugam, Bardsley, Michael R, Smestad, John A, Lorincz, Andrea, Eisenman, Seth T, Cipriani, Gianluca, Nelson Holte, Molly H, Al Khazal, Fatimah J, Syed, Sabriya A, Gajdos, Gabriella B, Choi, Kyoung Moo, Stoltz, Gary J, Miller, Katie E, Kendrick, Michael L, Rubin, Brian P, Gibbons, Simon J, Bharucha, Adil E, Linden, David R, Maher, Louis James, Farrugia, Gianrico, Ordog, Tamas
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2017)
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Journal Article
RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation
Oh, Raymond S, Haak, Andrew J, Smith, Karry M J, Ligresti, Giovanni, Choi, Kyoung Moo, Xie, Tiao, Wang, Shaohua, Walters, Paula R, Thompson, Michael A, Freeman, Michelle R, Manlove, Logan J, Chu, Vivian M, Feghali-Bostwick, Carol, Roden, Anja C, Schymeinsky, Jürgen, Pabelick, Christina M, Prakash, Y S, Vassallo, Robert, Tschumperlin, Daniel J
Published in Journal of cell science (15.05.2018)
Published in Journal of cell science (15.05.2018)
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Journal Article
Non‐canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells
Aravamudhan, Aja, Dieffenbach, Paul B., Choi, Kyoung Moo, Link, Patrick A., Meridew, Jeffrey A., Haak, Andrew J., Fredenburgh, Laura E., Tschumperlin, Daniel J.
Published in Physiological reports (01.04.2024)
Published in Physiological reports (01.04.2024)
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Journal Article
Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis
Gibbons, Simon J, Grover, Madhusudan, Choi, Kyoung Moo, Wadhwa, Akhilesh, Zubair, Adeel, Wilson, Laura A, Wu, Yanhong, Abell, Thomas L, Hasler, William L, Koch, Kenneth L, McCallum, Richard W, Nguyen, Linda A B, Parkman, Henry P, Sarosiek, Irene, Snape, William J, Tonascia, James, Hamilton, Frank A, Pasricha, Pankaj J, Farrugia, Gianrico
Published in PloS one (21.11.2017)
Published in PloS one (21.11.2017)
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Journal Article
Comparison of the epidemiology and injury profile among injured patients involved in special purpose vehicle-related incidents in South Korea
Chai, Hyun-Seok, Kim, Sang-Chul, Kong, So-Yeon, Park, Gwan-Jin, Lee, Ji-Han, Kim, Hoon, Lee, Seok-Woo, Lee, Hae-Ju, Choi, Kyoung-Moo
Published in Archives of environmental & occupational health (2021)
Published in Archives of environmental & occupational health (2021)
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Journal Article
Carbon monoxide reverses diabetic gastroparesis in NOD mice
Kashyap, Purna C, Choi, Kyoung Moo, Dutta, Nirjhar, Linden, David R, Szurszewski, Joseph H, Gibbons, Simon J, Farrugia, Gianrico
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2010)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2010)
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Journal Article
Effects of aspirin & simvastatin and aspirin, simvastatin, & lipoic acid on heme oxygenase‐1 in healthy human subjects
Bharucha, Adil E., Choi, Kyoung Moo, Saw, Jessica J., Gibbons, Simon J., Farrugia, Gianrico F., Carlson, David A., Zinsmeister, Alan R.
Published in Neurogastroenterology and motility (01.10.2014)
Published in Neurogastroenterology and motility (01.10.2014)
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Journal Article
Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice
Choi, Kyoung Moo, Gibbons, Simon J, Sha, Lei, Beyder, Arthur, Verhulst, Pieter-Jan, Cipriani, Gianluca, Phillips, Jessica E, Bauer, Anthony J, Ordog, Tamas, Camp, Jon J, Ge, Xin, Bharucha, Adil E, Linden, David R, Szurszewski, Joseph H, Kashyap, Purna C, Farrugia, Gianrico
Published in Cellular and molecular gastroenterology and hepatology (01.07.2016)
Published in Cellular and molecular gastroenterology and hepatology (01.07.2016)
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Journal Article
Human airway organoid engineering as a step toward lung regeneration and disease modeling
Tan, Qi, Choi, Kyoung Moo, Sicard, Delphine, Tschumperlin, Daniel J
Published in Biomaterials (01.01.2017)
Published in Biomaterials (01.01.2017)
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Journal Article
Aging and anatomical variations in lung tissue stiffness
Sicard, Delphine, Haak, Andrew J, Choi, Kyoung Moo, Craig, Alexandria R, Fredenburgh, Laura E, Tschumperlin, Daniel J
Published in American journal of physiology. Lung cellular and molecular physiology (01.06.2018)
Published in American journal of physiology. Lung cellular and molecular physiology (01.06.2018)
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Journal Article
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis
Haak, Andrew J, Kostallari, Enis, Sicard, Delphine, Ligresti, Giovanni, Choi, Kyoung Moo, Caporarello, Nunzia, Jones, Dakota L, Tan, Qi, Meridew, Jeffrey, Diaz Espinosa, Ana M, Aravamudhan, Aja, Maiers, Jessica L, Britt, Jr, Rodney D, Roden, Anja C, Pabelick, Christina M, Prakash, Y S, Nouraie, Seyed Mehdi, Li, Xiaoyun, Zhang, Yingze, Kass, Daniel J, Lagares, David, Tager, Andrew M, Varelas, Xaralabos, Shah, Vijay H, Tschumperlin, Daniel J
Published in Science translational medicine (30.10.2019)
Published in Science translational medicine (30.10.2019)
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Journal Article
Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2
Dieffenbach, Paul B, Haeger, Christina Mallarino, Coronata, Anna Maria F, Choi, Kyoung Moo, Varelas, Xaralabos, Tschumperlin, Daniel J, Fredenburgh, Laura E
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2017)
Published in American journal of physiology. Lung cellular and molecular physiology (01.09.2017)
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Journal Article
TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation
Aravamudhan, Aja, Haak, Andrew J, Choi, Kyoung Moo, Meridew, Jeffrey A, Caporarello, Nunzia, Jones, Dakota L, Tan, Qi, Ligresti, Giovanni, Tschumperlin, Daniel J
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2020)
Published in American journal of physiology. Lung cellular and molecular physiology (01.05.2020)
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Journal Article
Combined control of the fibroblast contractile program by YAP and TAZ
Link, Patrick A, Choi, Kyoung Moo, Diaz Espinosa, Ana M, Jones, Dakota L, Gao, Ashley Y, Haak, Andrew J, Tschumperlin, Daniel J
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2022)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2022)
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Journal Article