Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules
Luker, Tim, Alcaraz, Lilian, Chohan, Kamaldeep K., Blomberg, Niklas, Brown, Dearg S., Butlin, Roger J., Elebring, Thomas, Griffin, Andrew M., Guile, Simon, St-Gallay, Stephen, Swahn, Britt-Marie, Swallow, Steve, Waring, Michael J., Wenlock, Mark C., Leeson, Paul D.
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
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Journal Article
Quantitative structure activity relationships in drug metabolism
Chohan, Kamaldeep K, Paine, Stuart W, Waters, Nigel J
Published in Current topics in medicinal chemistry (01.08.2006)
Published in Current topics in medicinal chemistry (01.08.2006)
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Journal Article
Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models
Gleeson, M Paul, Davis, Andrew M, Chohan, Kamaldeep K, Paine, Stuart W, Boyer, Scott, Gavaghan, Claire L, Arnby, Catrin Hasselgren, Kankkonen, Cecilia, Albertson, Nan
Published in Journal of computer-aided molecular design (01.10.2007)
Published in Journal of computer-aided molecular design (01.10.2007)
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Journal Article
A rapid computational filter for predicting the rate of human renal clearance
Paine, Stuart W., Barton, Patrick, Bird, James, Denton, Rebecca, Menochet, Karelle, Smith, Aaron, Tomkinson, Nicholas P., Chohan, Kamaldeep K.
Published in Journal of molecular graphics & modelling (01.12.2010)
Published in Journal of molecular graphics & modelling (01.12.2010)
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Journal Article
QM/MM Studies Show Substantial Tunneling for the Hydrogen-Transfer Reaction in Methylamine Dehydrogenase
Faulder, Paul F, Tresadern, Gary, Chohan, Kamaldeep K, Scrutton, Nigel S, Sutcliffe, Michael J, Hillier, Ian H, Burton, Neil A
Published in Journal of the American Chemical Society (05.09.2001)
Published in Journal of the American Chemical Society (05.09.2001)
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Journal Article
Structure of the Complex of Cdc42Hs with a Peptide Derived from P-21 Activated Kinase
Gizachew, Dawit, Guo, Wei, Chohan, Kamaldeep K, Sutcliffe, Michael J, Oswald, Robert E
Published in Biochemistry (Easton) (11.04.2000)
Published in Biochemistry (Easton) (11.04.2000)
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Journal Article
Differential Coupling through Val-344 and Tyr-442 of Trimethylamine Dehydrogenase in Electron Transfer Reactions with Ferricenium Ions and Electron Transferring Flavoprotein
Basran, Jaswir, Chohan, Kamaldeep K, Sutcliffe, Michael J, Scrutton, Nigel S
Published in Biochemistry (Easton) (08.08.2000)
Published in Biochemistry (Easton) (08.08.2000)
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Journal Article
CDK 억제제로서 치환된 피라졸로[1,5-A]피리미딘-7-아민 화합물 및 이들의 치료적 용도
SUNOSE MIHIRO, BAHL ASHWANI, CHOHAN KAMALDEEP KAUR, CREPIN DAMIEN FRANCIS PHILIPPE, TOSCHI GIANNA, AINSCOW EDWARD
Year of Publication 19.02.2024
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Year of Publication 19.02.2024
Patent
약학적 화합물
COWLEY PHILLIP MARTIN, WISE ALAN, CHOHAN KAMALDEEP KAUR, MCGUINNESS BARRY EDWARD, JOUANNEAU MORGAN, JORDAN ALLAN MICHAEL
Year of Publication 20.12.2023
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Year of Publication 20.12.2023
Patent
Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate
Furber, Mark, Tiden, Anna-Karin, Gardiner, Philip, Mete, Antonio, Ford, Rhonan, Millichip, Ian, Stein, Linda, Mather, Andrew, Kinchin, Elizabeth, Luckhurst, Christopher, Barber, Simon, Cage, Peter, Sanganee, Hitesh, Austin, Rupert, Chohan, Kamaldeep, Beri, Raj, Thong, Bob, Wallace, Alan, Oreffo, Victor, Hutchinson, Ray, Harper, Steve, Debreczeni, Judit, Breed, Jason, Wissler, Lisa, Edman, Karl
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
통합된 스트레스 경로의 조절인자
CHOHAN KAMALDEEP K, SIDRAUSKI CARMELA, TONG YUNSONG, SHI LEI, SCHWENK SEBASTIAN, RANDOLPH JOHN T, XU XIANGDONG, DART MICHAEL J, BENELKEBIR HANAE, STARBUCK KATHRYN A, MURAUSKI KATHLEEN J, EDESON STEVEN J, MARTIN KATHLEEN ANN, SMITH RUSSELL C
Year of Publication 04.08.2023
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Year of Publication 04.08.2023
Patent
Flavin radicals, conformational sampling and robust design principles in interprotein electron transfer: the trimethylamine dehydrogenase-electron-transferring flavoprotein complex
Leys, David, Basran, Jaswir, Talfournier, François, Chohan, Kamaldeep K, Munro, Andrew W, Sutcliffe, Michael J, Scrutton, Nigel S
Published in Biochemical Society Symposia (01.01.2004)
Published in Biochemical Society Symposia (01.01.2004)
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Journal Article
Cysteine Mutagenesis and Homology Modeling of the Ligand-binding Site of a Kainate-binding Protein
Wo, Z G, Chohan, K K, Chen, H, Sutcliffe, M J, Oswald, R E
Published in The Journal of biological chemistry (24.12.1999)
Published in The Journal of biological chemistry (24.12.1999)
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Journal Article
Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists
Luckhurst, Christopher A., Ratcliffe, Marianne, Stein, Linda, Furber, Mark, Botterell, Sara, Laughton, David, Tomlinson, Wendy, Weaver, Richard, Chohan, Kamaldeep, Walding, Andrew
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
PHARMACEUTICAL COMPOUND
McGuiness, Barry Edward, Jouanneau, Morgan, Wise, Alan, Chohan, Kamaldeep Kaur, Jordan, Allan Michael, Cowley, Phillip Martin
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
PHARMACEUTICAL COMPOUND
MCGUINNESS, Barry Edward, JORDAN, Allan Michael, CHOHAN, Kamaldeep Kaur, JOUANNEAU, Morgan, COWLEY, Phillip Martin, WISE, Alan
Year of Publication 07.02.2024
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Year of Publication 07.02.2024
Patent