The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition
Goodwin, Justin, Neugent, Michael L., Lee, Shin Yup, Choe, Joshua H., Choi, Hyunsung, Jenkins, Dana M. R., Ruthenborg, Robin J., Robinson, Maddox W., Jeong, Ji Yun, Wake, Masaki, Abe, Hajime, Takeda, Norihiko, Endo, Hiroko, Inoue, Masahiro, Xuan, Zhenyu, Yoo, Hyuntae, Chen, Min, Ahn, Jung-Mo, Minna, John D., Helke, Kristi L., Singh, Pankaj K., Shackelford, David B., Kim, Jung-whan
Published in Nature communications (26.05.2017)
Published in Nature communications (26.05.2017)
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Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers
Katz, Chen, Low-Calle, Ana Maria, Choe, Joshua H, Laptenko, Oleg, Tong, David, Joseph-Chowdhury, Jazmine-Saskya N, Garofalo, Francesca, Zhu, Yan, Friedler, Assaf, Prives, Carol
Published in Genes & development (01.03.2018)
Published in Genes & development (01.03.2018)
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p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
Hsieh, Meng-Hsiung, Choe, Joshua H., Gadhvi, Jashkaran, Kim, Yoon Jung, Arguez, Marcus A., Palmer, Madison, Gerold, Haleigh, Nowak, Chance, Do, Hung, Mazambani, Simbarashe, Knighton, Jordan K., Cha, Matthew, Goodwin, Justin, Kang, Min Kyu, Jeong, Ji Yun, Lee, Shin Yup, Faubert, Brandon, Xuan, Zhenyu, Abel, E. Dale, Scafoglio, Claudio, Shackelford, David B., Minna, John D., Singh, Pankaj K., Shulaev, Vladimir, Bleris, Leonidas, Hoyt, Kenneth, Kim, James, Inoue, Masahiro, DeBerardinis, Ralph J., Kim, Tae Hoon, Kim, Jung-whan
Published in Cell reports (Cambridge) (13.08.2019)
Published in Cell reports (Cambridge) (13.08.2019)
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Li-Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Choe, Joshua H, Kawase, Tatsuya, Xu, An, Guzman, Asja, Obradovic, Aleksandar Z, Low-Calle, Ana Maria, Alaghebandan, Bita, Raghavan, Ananya, Long, Kaitlin, Hwang, Paul M, Schiffman, Joshua D, Zhu, Yan, Zhao, Ruiying, Lee, Dung-Fang, Katz, Chen, Prives, Carol
Published in Cancer discovery (04.05.2023)
Published in Cancer discovery (04.05.2023)
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Abstract LB361: Li-Fraumeni syndrome-associated dimer-forming mutant p53 promotes transactivation-independent mitochondrial cell death
Choe, Joshua H., Kawase, Tatsuya, Xu, An, Guzman, Asja, Tong, David R., Obradovic, Aleksandar Z., Low-Calle, Ana M., Alaghebandan, Bita, Raghavan, Ananya, Long, Kaitlin, Hwang, Paul M., Schiffman, Joshua D., Zhu, Yan, Zhao, Ruiying, Lee, Dung-Fang, Katz, Chen, Prives, Carol L.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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