Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions
Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyein S., Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel A., Chen, Tingxu, Li, Qing V., Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei, Beer, Michael A.
Published in Nature genetics (01.08.2023)
Published in Nature genetics (01.08.2023)
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Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, Bess P., Li, Qing V., Cho, Hyein S., Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R., Kale, Hanuman T., Kaplan, Samuel J., Beer, Michael A., Sidoli, Simone, Huangfu, Danwei
Published in Nature communications (17.10.2024)
Published in Nature communications (17.10.2024)
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CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
Kaplan, Samuel Joseph, Wong, Wilfred, Yan, Jielin, Pulecio, Julian, Cho, Hyein S., Li, Qianzi, Zhao, Jiahui, Leslie-Iyer, Jayanti, Kazakov, Jonathan, Murphy, Dylan, Luo, Renhe, Dey, Kushal K., Apostolou, Effie, Leslie, Christina S., Huangfu, Danwei
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
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An epigenetic barrier sets the timing of human neuronal maturation
Ciceri, Gabriele, Baggiolini, Arianna, Cho, Hyein S., Kshirsagar, Meghana, Benito-Kwiecinski, Silvia, Walsh, Ryan M., Aromolaran, Kelly A., Gonzalez-Hernandez, Alberto J., Munguba, Hermany, Koo, So Yeon, Xu, Nan, Sevilla, Kaylin J., Goldstein, Peter A., Levitz, Joshua, Leslie, Christina S., Koche, Richard P., Studer, Lorenz
Published in Nature (London) (22.02.2024)
Published in Nature (London) (22.02.2024)
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TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
Kim, Tae Wan, Koo, So Yeon, Riessland, Markus, Chaudhry, Fayzan, Kolisnyk, Benjamin, Cho, Hyein S., Russo, Marco Vincenzo, Saurat, Nathalie, Mehta, Sanjoy, Garippa, Ralph, Betel, Doron, Studer, Lorenz
Published in Cell (11.07.2024)
Published in Cell (11.07.2024)
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CRISPR Screening Uncovers a Long-Range Enhancer for ONECUT1 in Pancreatic Differentiation and Links a Diabetes Risk Variant
Kaplan, Samuel Joseph, Wong, Wilfred, Yan, Jielin, Pulecio, Julian, Cho, Hyein S, Li, Qianzi, Zhao, Jiahui, Leslie-Iyer, Jayanti, Kazakov, Jonathan, Murphy, Dylan, Luo, Renhe, Dey, Kushal K, Apostolou, Effie, Leslie, Christina S, Huangfu, Danwei
Published in bioRxiv (28.06.2024)
Published in bioRxiv (28.06.2024)
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Journal Article
Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, Bess P, Li, Qing V, Cho, Hyein S, Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R, Kale, Hanuman T, Kaplan, Samuel J, Beer, Michael A, Sidoli, Simone, Huangfu, Danwei
Published in bioRxiv (01.09.2024)
Published in bioRxiv (01.09.2024)
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