Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound
Anang, Saumya, Richard, Jonathan, Bourassa, Catherine, Goyette, Guillaume, Chiu, Ta-Jung, Chen, Hung-Ching, Smith, 3rd, Amos B, Madani, Navid, Finzi, Andrés, Sodroski, Joseph
Published in Journal of virology (14.09.2022)
Published in Journal of virology (14.09.2022)
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NTB-A and 2B4 Natural Killer Cell Receptors Modulate the Capacity of a Cocktail of Non-Neutralizing Antibodies and a Small CD4-Mimetic to Eliminate HIV-1-Infected Cells by Antibody-Dependent Cellular Cytotoxicity
Marchitto, Lorie, Tauzin, Alexandra, Benlarbi, Mehdi, Beaudoin-Bussières, Guillaume, Dionne, Katrina, Bélanger, Étienne, Chatterjee, Debashree, Bourassa, Catherine, Medjahed, Halima, Yang, Derek, Chiu, Ta-Jung, Chen, Hung-Ching, III, Amos B. Smith, Richard, Jonathan, Finzi, Andrés
Published in Viruses (01.07.2024)
Published in Viruses (01.07.2024)
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Alterations in gp120 glycans or the gp41 fusion peptide-proximal region modulate the stability of the human immunodeficiency virus (HIV-1) envelope glycoprotein pretriggered conformation
Zhang, Zhiqing, Wang, Qian, Nguyen, Hanh T, Chen, Hung-Ching, Chiu, Ta-Jung, Smith Iii, Amos B, Sodroski, Joseph G
Published in Journal of virology (28.09.2023)
Published in Journal of virology (28.09.2023)
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V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins
Anang, Saumya, Zhang, Shijian, Fritschi, Christopher, Chiu, Ta-Jung, Yang, Derek, Smith Iii, Amos B, Madani, Navid, Sodroski, Joseph
Published in Journal of virology (30.11.2023)
Published in Journal of virology (30.11.2023)
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Global Increases in Human Immunodeficiency Virus Neutralization Sensitivity Due to Alterations in the Membrane-Proximal External Region of the Envelope Glycoprotein Can Be Minimized by Distant State 1-Stabilizing Changes
Wang, Qian, Esnault, Florian, Zhao, Meiqing, Chiu, Ta-Jung, Smith, 3rd, Amos B, Nguyen, Hanh T, Sodroski, Joseph G
Published in Journal of virology (13.04.2022)
Published in Journal of virology (13.04.2022)
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Functional and Highly Cross-Linkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation
Nguyen, Hanh T, Qualizza, Alessandra, Anang, Saumya, Zhao, Meiqing, Zou, Shitao, Zhou, Rong, Wang, Qian, Zhang, Shijian, Deshpande, Ashlesha, Ding, Haitao, Chiu, Ta-Jung, Smith, 3rd, Amos B, Kappes, John C, Sodroski, Joseph G
Published in Journal of virology (27.04.2022)
Published in Journal of virology (27.04.2022)
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Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity
Fritschi, Christopher J, Anang, Saumya, Gong, Zhen, Mohammadi, Mohammadjavad, Richard, Jonathan, Bourassa, Catherine, Severino, Kenny T, Richter, Hannah, Yang, Derek, Chen, Hung-Ching, Chiu, Ta-Jung, Seaman, Michael S, Madani, Navid, Abrams, Cameron, Finzi, Andrés, Hendrickson, Wayne A, Sodroski, Joseph G, Smith, 3rd, Amos B
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2023)
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Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics
Tauzin, Alexandra, Marchitto, Lorie, Bélanger, Étienne, Benlarbi, Mehdi, Beaudoin-Bussières, Guillaume, Prévost, Jérémie, Yang, Derek, Chiu, Ta-Jung, Chen, Hung-Ching, Bourassa, Catherine, Medjahed, Halima, Korzeniowski, Marek K., Gottumukkala, Suneetha, Tolbert, William D., Richard, Jonathan, Smith, Amos B., Pazgier, Marzena, Finzi, Andrés
Published in Journal of virology (04.09.2024)
Published in Journal of virology (04.09.2024)
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Journal Article
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity
Marchitto, Lorie, Richard, Jonathan, Prévost, Jérémie, Tauzin, Alexandra, Yang, Derek, Chiu, Ta-Jung, Chen, Hung-Ching, Díaz-Salinas, Marco A., Nayrac, Manon, Benlarbi, Mehdi, Beaudoin-Bussières, Guillaume, Anand, Sai Priya, Dionne, Katrina, Bélanger, Étienne, Chatterjee, Debashree, Medjahed, Halima, Bourassa, Catherine, Tolbert, William D., Hahn, Beatrice H., Munro, James B., Pazgier, Marzena, Smith, Amos B., Finzi, Andrés
Published in Journal of virology (09.09.2024)
Published in Journal of virology (09.09.2024)
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Journal Article
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC
Richard, Jonathan, Grunst, Michael W, Niu, Ling, Díaz-Salinas, Marco A, Tolbert, William D, Marchitto, Lorie, Zhou, Fei, Bourassa, Catherine, Yang, Derek, Chiu, Ta Jung, Chen, Hung-Ching, Benlarbi, Mehdi, Gottumukkala, Suneetha, Li, Wenwei, Dionne, Katrina, Bélanger, Étienne, Chatterjee, Debashree, Medjahed, Halima, Hendrickson, Wayne A, Sodroski, Joseph, Lang, Zabrina C, Morton, Abraham J, Huang, Rick K, Matthies, Doreen, Smith, Amos B, Mothes, Walther, Munro, James B, Pazgier, Marzena, Finzi, Andrés
Published in bioRxiv (27.08.2024)
Published in bioRxiv (27.08.2024)
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Journal Article
Characterization of human immunodeficiency virus (HIV-1) envelope glycoprotein variants selected for resistance to a CD4-mimetic compound
Anang, Saumya, Richard, Jonathan, Bourassa, Catherine, Goyette, Guillaume, Ta-Jung, Chiu, Hung-Ching, Chen, Smith, Amos B, Madani, Navid, Finzi, Andrés, Sodroski, Joseph G
Published in bioRxiv (23.04.2022)
Published in bioRxiv (23.04.2022)
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