Antibody Structure and Function: The Basis for Engineering Therapeutics
Chiu, Mark L, Goulet, Dennis R, Teplyakov, Alexey, Gilliland, Gary L
Published in Antibodies (Basel) (03.12.2019)
Published in Antibodies (Basel) (03.12.2019)
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Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET
Neijssen, Joost, Cardoso, Rosa M.F., Chevalier, Kristen M., Wiegman, Luus, Valerius, Thomas, Anderson, G. Mark, Moores, Sheri L., Schuurman, Janine, Parren, Paul W.H.I., Strohl, William R., Chiu, Mark L.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody
Zhang, Di, Goldberg, Monica V., Chiu, Mark L.
Published in The Journal of biological chemistry (30.12.2016)
Published in The Journal of biological chemistry (30.12.2016)
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Journal Article
A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors
Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark
Published in Cancer research (Chicago, Ill.) (01.07.2016)
Published in Cancer research (Chicago, Ill.) (01.07.2016)
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Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models
Labrijn, Aran F., Meesters, Joyce I., Bunce, Matthew, Armstrong, Anthony A., Somani, Sandeep, Nesspor, Tom C., Chiu, Mark L., Altintaş, Işil, Verploegen, Sandra, Schuurman, Janine, Parren, Paul W. H. I.
Published in Scientific reports (30.05.2017)
Published in Scientific reports (30.05.2017)
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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality
Tam, Susan, McCarthy, Stephen, Armstrong, Anthony, Somani, Sandeep, Wu, Sheng-Jiun, Liu, Xuesong, Gervais, Alexis, Ernst, Robin, Saro, Dorina, Decker, Rose, Luo, Jinquan, Gilliland, Gary, Chiu, Mark, Scallon, Bernard
Published in Antibodies (Basel) (01.09.2017)
Published in Antibodies (Basel) (01.09.2017)
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Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody
Hinke, Simon A., Cieniewicz, Anne M., Kirchner, Thomas, D'Aquino, Katharine, Nanjunda, Rupesh, Aligo, Jason, Perkinson, Robert, Cooper, Philip, Boayke, Ken, Chiu, Mark L., Jarantow, Steve, Lacy, Eilyn R., Liang, Yin, Johnson, Dana L., Whaley, Jean M., Lingham, Russell B., Kihm, Anthony J.
Published in Molecular metabolism (Germany) (01.04.2018)
Published in Molecular metabolism (Germany) (01.04.2018)
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A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function
Zhou, Fulai, Ben, Yinyin, Jiang, Hao, Tan, Siwen, Mu, Guangmao, Zha, Zhengxia, Dong, Shuting, Huang, Sheng, Zhou, Yijun, Jin, Ying, Chiu, Mark L.
Published in Biochemistry (Easton) (16.04.2024)
Published in Biochemistry (Easton) (16.04.2024)
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Phase 1 Safety and Pharmacokinetics Study of TAVO101, an Anti-Human Thymic Stromal Lymphopoietin Antibody for the Treatment of Allergic Inflammatory Conditions
Han, Chao, Fung, Isa, Zhang, Di, Jin, Ying, Chen, Peng, Tam, Susan, Chiu, Mark L, Fung, Man-Cheong
Published in Journal of clinical pharmacology (14.08.2024)
Published in Journal of clinical pharmacology (14.08.2024)
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Journal Article
Fc-mediated activity of EGFR x c-Met bispecific antibody JNJ-61186372 enhanced killing of lung cancer cells
Grugan, Katharine D, Dorn, Keri, Jarantow, Stephen W, Bushey, Barbara S, Pardinas, Jose R, Laquerre, Sylvie, Moores, Sheri L, Chiu, Mark L
Published in mAbs (01.01.2017)
Published in mAbs (01.01.2017)
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Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance
Goulet, Dennis R, Watson, Michael J, Tam, Susan H, Zwolak, Adam, Chiu, Mark L, Atkins, William M, Nath, Abhinav
Published in Drug metabolism and disposition (01.12.2018)
Published in Drug metabolism and disposition (01.12.2018)
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Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors
Derebe, Mehabaw G., Nanjunda, Rupesh K., Gilliland, Gary L., Lacy, Eilyn R., Chiu, Mark L.
Published in Immunology letters (01.05.2018)
Published in Immunology letters (01.05.2018)
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Journal Article
Influence of the bispecific antibody IgG subclass on T cell redirection
Kapelski, Stephanie, Cleiren, Erna, Attar, Ricardo M, Philippar, Ulrike, Häsler, Julien, Chiu, Mark L
Published in mAbs (18.08.2019)
Published in mAbs (18.08.2019)
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Journal Article
An efficient process of generating bispecific antibodies via controlled Fab-arm exchange using culture supernatants
Paul, Suparna, Connor, Judy, Nesspor, Tom, Haytko, Peter, Boakye, Ken, Chiu, Mark L., Jiang, Haiyan
Published in Protein expression and purification (01.05.2016)
Published in Protein expression and purification (01.05.2016)
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