The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases
Hogan, Kelly A, Chini, Claudia C S, Chini, Eduardo N
Published in Frontiers in immunology (31.05.2019)
Published in Frontiers in immunology (31.05.2019)
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Journal Article
Targeting of NAD Metabolism in Pancreatic Cancer Cells: Potential Novel Therapy for Pancreatic Tumors
CHINI, Claudia C. S, GUERRICO, Anatilde M. Gonzalez, NIN, Veronica, CAMACHO-PEREIRA, Juliana, ESCANDE, Carlos, BARBOSA, Maria Thereza, CHINI, Eduardo N
Published in Clinical cancer research (01.01.2014)
Published in Clinical cancer research (01.01.2014)
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Journal Article
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD + and NMN levels
Chini, Claudia C S, Peclat, Thais R, Warner, Gina M, Kashyap, Sonu, Espindola-Netto, Jair Machado, de Oliveira, Guilherme C, Gomez, Lilian S, Hogan, Kelly A, Tarragó, Mariana G, Puranik, Amrutesh S, Agorrody, Guillermo, Thompson, Katie L, Dang, Kevin, Clarke, Starlynn, Childs, Bennett G, Kanamori, Karina S, Witte, Micaela A, Vidal, Paola, Kirkland, Anna L, De Cecco, Marco, Chellappa, Karthikeyani, McReynolds, Melanie R, Jankowski, Connor, Tchkonia, Tamara, Kirkland, James L, Sedivy, John M, van Deursen, Jan M, Baker, Darren J, van Schooten, Wim, Rabinowitz, Joshua D, Baur, Joseph A, Chini, Eduardo N
Published in Nature metabolism (01.11.2020)
Published in Nature metabolism (01.11.2020)
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Journal Article
CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype
de Zélicourt, Antoine, Fayssoil, Abdallah, Dakouane‐Giudicelli, Mbarka, De Jesus, Isley, Karoui, Ahmed, Zarrouki, Faouzi, Lefebvre, Florence, Mansart, Arnaud, Launay, Jean‐Marie, Piquereau, Jerome, Tarragó, Mariana G, Bonay, Marcel, Forand, Anne, Moog, Sophie, Piétri‐Rouxel, France, Brisebard, Elise, Chini, Claudia C S, Kashyap, Sonu, Fogarty, Matthew J, Sieck, Gary C, Mericskay, Mathias, Chini, Eduardo N, Gomez, Ana Maria, Cancela, José‐Manuel, de la Porte, Sabine
Published in EMBO molecular medicine (09.05.2022)
Published in EMBO molecular medicine (09.05.2022)
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Journal Article
CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging
Peclat, Thais R., Thompson, Katie L., Warner, Gina M., Chini, Claudia C.S., Tarragó, Mariana G., Mazdeh, Delaram Z., Zhang, Chunlian, Zavala‐Solorio, Jose, Kolumam, Ganesh, Liang Wong, Yao, Cohen, Robert L., Chini, Eduardo N.
Published in Aging cell (01.04.2022)
Published in Aging cell (01.04.2022)
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Journal Article
Dihydronicotinamide Riboside Is a Potent NAD + Precursor Promoting a Pro-Inflammatory Phenotype in Macrophages
Chini, Claudia C S, Peclat, Thais R, Gomez, Lilian S, Zeidler, Julianna D, Warner, Gina M, Kashyap, Sonu, Mazdeh, Delaram Z, Hayat, Faisal, Migaud, Marie E, Paulus, Aneel, Chanan-Khan, Asher A, Chini, Eduardo N
Published in Frontiers in immunology (25.02.2022)
Published in Frontiers in immunology (25.02.2022)
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Journal Article
An NAD + -dependent metabolic checkpoint regulates hematopoietic stem cell activation and aging
Song, Zehan, Park, Sang Hee, Mu, Wei-Chieh, Feng, Yufan, Wang, Chih-Ling, Wang, Yifei, Barthez, Marine, Maruichi, Ayane, Guo, Jiayue, Yang, Fanghan, Lin, Anita Wong, Heydari, Kartoosh, Chini, Claudia C S, Chini, Eduardo N, Jang, Cholsoon, Chen, Danica
Published in Nature aging (01.10.2024)
Published in Nature aging (01.10.2024)
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Journal Article
Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer
Chini, Eduardo Nunes, Chini, Claudia C S, Nin, Veronica, Escande, Carlos
Published in Bioscience reports (23.08.2013)
Published in Bioscience reports (23.08.2013)
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Journal Article
SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent Pathway
Chini, Claudia C S, Espindola-Netto, Jair M, Mondal, Gourish, Guerrico, Anatilde M Gonzalez, Nin, Veronica, Escande, Carlos, Sola-Penna, Mauro, Zhang, Jin-San, Billadeau, Daniel D, Chini, Eduardo N
Published in Clinical cancer research (15.05.2016)
Published in Clinical cancer research (15.05.2016)
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Journal Article
Evolving concepts in NAD + metabolism
Chini, Claudia C S, Zeidler, Julianna D, Kashyap, Sonu, Warner, Gina, Chini, Eduardo Nunes
Published in Cell metabolism (01.06.2021)
Published in Cell metabolism (01.06.2021)
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Journal Article
Deleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotype
Escande, Carlos, Nin, Veronica, Pirtskhalava, Tamar, Chini, Claudia C S, Tchkonia, Tamar, Kirkland, James L, Chini, Eduardo N
Published in Diabetes (New York, N.Y.) (01.01.2015)
Published in Diabetes (New York, N.Y.) (01.01.2015)
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Journal Article
NAD and the aging process: Role in life, death and everything in between
Chini, Claudia C.S., Tarragó, Mariana G., Chini, Eduardo N.
Published in Molecular and cellular endocrinology (05.11.2017)
Published in Molecular and cellular endocrinology (05.11.2017)
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Journal Article
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism
Camacho-Pereira, Juliana, Tarragó, Mariana G., Chini, Claudia C.S., Nin, Veronica, Escande, Carlos, Warner, Gina M., Puranik, Amrutesh S., Schoon, Renee A., Reid, Joel M., Galina, Antonio, Chini, Eduardo N.
Published in Cell metabolism (14.06.2016)
Published in Cell metabolism (14.06.2016)
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Journal Article
The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging
Chini, Eduardo N., Chini, Claudia C.S., Espindola Netto, Jair Machado, de Oliveira, Guilherme C., van Schooten, Wim
Published in Trends in pharmacological sciences (Regular ed.) (01.04.2018)
Published in Trends in pharmacological sciences (Regular ed.) (01.04.2018)
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Journal Article
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
Tarragó, Mariana G., Chini, Claudia C.S., Kanamori, Karina S., Warner, Gina M., Caride, Ariel, de Oliveira, Guilherme C., Rud, Micaela, Samani, Adrienne, Hein, Kyaw Z., Huang, Runqing, Jurk, Diana, Cho, Dong Seong, Boslett, James J., Miller, Jordan D., Zweier, Jay L., Passos, João F., Doles, Jason D., Becherer, David J., Chini, Eduardo N.
Published in Cell metabolism (01.05.2018)
Published in Cell metabolism (01.05.2018)
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Journal Article
Food Restriction Ameliorates the Development of Polycystic Kidney Disease
Warner, Gina, Hein, Kyaw Zaw, Nin, Veronica, Edwards, Marika, Chini, Claudia C S, Hopp, Katharina, Harris, Peter C, Torres, Vicente E, Chini, Eduardo N
Published in Journal of the American Society of Nephrology (01.05.2016)
Published in Journal of the American Society of Nephrology (01.05.2016)
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Journal Article
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions
Zeidler, Julianna D, Hogan, Kelly A, Agorrody, Guillermo, Peclat, Thais R, Kashyap, Sonu, Kanamori, Karina S, Gomez, Lilian Sales, Mazdeh, Delaram Z, Warner, Gina M, Thompson, Katie L, Chini, Claudia C S, Chini, Eduardo Nunes
Published in American Journal of Physiology: Cell Physiology (01.03.2022)
Published in American Journal of Physiology: Cell Physiology (01.03.2022)
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Journal Article
Ecto-CD38-NADase inhibition modulates cardiac metabolism and protects mice against doxorubicin-induced cardiotoxicity
Peclat, Thais R, Agorrody, Guillermo, Colman, Laura, Kashyap, Sonu, Zeidler, Julianna D, Chini, Claudia C S, Warner, Gina M, Thompson, Katie L, Dalvi, Pranjali, Beckedorff, Felipe, Ebtehaj, Sanam, Herrmann, Joerg, van Schooten, Wim, Chini, Eduardo Nunes
Published in Cardiovascular research (14.03.2024)
Published in Cardiovascular research (14.03.2024)
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