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Motzer, Robert J., Robbins, Paul B., Powles, Thomas, Albiges, Laurence, Haanen, John B., Larkin, James, Mu, Xinmeng Jasmine, Ching, Keith A., Uemura, Motohide, Pal, Sumanta K., Alekseev, Boris, Gravis, Gwenaelle, Campbell, Matthew T., Penkov, Konstantin, Lee, Jae Lyun, Hariharan, Subramanian, Wang, Xiao, Zhang, Weidong, Wang, Jing, Chudnovsky, Aleksander, di Pietro, Alessandra, Donahue, Amber C., Choueiri, Toni K.
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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Avelumab maintenance in advanced urothelial carcinoma: biomarker analysis of the phase 3 JAVELIN Bladder 100 trial
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Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome
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Published in Nature communications (02.12.2020)
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Histone modifications at human enhancers reflect global cell-type-specific gene expression
Ren, Bing, Heintzman, Nathaniel D, Hon, Gary C, Hawkins, R. David, Kheradpour, Pouya, Stark, Alexander, Harp, Lindsey F, Ye, Zhen, Lee, Leonard K, Stuart, Rhona K, Ching, Christina W, Ching, Keith A, Antosiewicz-Bourget, Jessica E, Liu, Hui, Zhang, Xinmin, Green, Roland D, Lobanenkov, Victor V, Stewart, Ron, Thomson, James A, Crawford, Gregory E, Kellis, Manolis
Published in Nature (07.05.2009)
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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
Ren, Bing, Heintzman, Nathaniel D, Stuart, Rhona K, Hon, Gary, Fu, Yutao, Ching, Christina W, Hawkins, R David, Barrera, Leah O, Van Calcar, Sara, Qu, Chunxu, Ching, Keith A, Wang, Wei, Weng, Zhiping, Green, Roland D, Crawford, Gregory E
Published in Nature genetics (01.03.2007)
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Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome
Kim, Tae Hoon, Abdullaev, Ziedulla K., Smith, Andrew D., Ching, Keith A., Loukinov, Dmitri I., Green, Roland D., Zhang, Michael Q., Lobanenkov, Victor V., Ren, Bing
Published in Cell (23.03.2007)
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Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
Metz, Patrick J., Ching, Keith A., Xie, Tao, Delgado Cuenca, Paulina, Niessen, Sherry, Tatlock, John H., Jensen-Pergakes, Kristen, Murray, Brion W.
Published in Cell reports (Cambridge) (11.02.2020)
Published in Cell reports (Cambridge) (11.02.2020)
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Molecular characterization of renal cell carcinoma tumors from a phase III anti-angiogenic adjuvant therapy trial
Motzer, Robert J., Martini, Jean-François, Mu, Xinmeng J., Staehler, Michael, George, Daniel J., Valota, Olga, Lin, Xun, Pandha, Hardev S., Ching, Keith A., Ravaud, Alain
Published in Nature communications (10.10.2022)
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A Gene Atlas of the Mouse and Human Protein-Encoding Transcriptomes
Su, Andrew I., Wiltshire, Tim, Batalov, Serge, Lapp, Hilmar, Ching, Keith A., Block, David, Zhang, Jie, Soden, Richard, Hayakawa, Mimi, Kreiman, Gabriel, Cooke, Michael P., Walker, John R., Hogenesch, John B., Vogt, Peter K.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
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An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735
Hook, Kenneth E, Garza, Scott J, Lira, Maruja E, Ching, Keith A, Lee, Nathan V, Cao, Joan, Yuan, Jing, Ye, Jingjing, Ozeck, Mark, Shi, Stephanie T, Zheng, Xianxian, Rejto, Paul A, Kan, Julie L C, Christensen, James G, Pavlicek, Adam
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
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Large-Scale Analysis of the Human and Mouse Transcriptomes
Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, Orth, Anthony P., Vega, Raquel G., Sapinoso, Lisa M., Moqrich, Aziz, Patapoutian, Ardem, Hampton, Garret M., Schultz, Peter G., Hogenesch, John B.
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2002)
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Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency
Hawkins, R David, Hon, Gary C, Yang, Chuhu, Antosiewicz-Bourget, Jessica E, Lee, Leonard K, Ngo, Que-Minh, Klugman, Sarit, Ching, Keith A, Edsall, Lee E, Ye, Zhen, Kuan, Samantha, Yu, Pengzhi, Liu, Hui, Zhang, Xinmin, Green, Roland D, Lobanenkov, Victor V, Stewart, Ron, Thomson, James A, Ren, Bing
Published in Cell research (01.10.2011)
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A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation
Lee, Nathan V, Lira, Maruja E, Pavlicek, Adam, Ye, Jingjing, Buckman, Dana, Bagrodia, Shubha, Srinivasa, Sreesha P, Zhao, Yongjun, Aparicio, Samuel, Rejto, Paul A, Christensen, James G, Ching, Keith A
Published in PloS one (22.06.2012)
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Ubiquitin-Mediated Sequestration of Normal Cellular Proteins into Polyglutamine Aggregates
Donaldson, Kathryn M., Li, Wei, Ching, Keith A., Batalov, Serge, Tsai, Chih-Cheng, Claudio A. P. Joazeiro
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
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First-in-Human Study of Utomilumab, a 4-1BB/CD137 Agonist, in Combination with Rituximab in Patients with Follicular and Other CD20 + Non-Hodgkin Lymphomas
Gopal, Ajay K, Levy, Ronald, Houot, Roch, Patel, Sandip P, Popplewell, Leslie, Jacobson, Caron, Mu, Xinmeng J, Deng, Shibing, Ching, Keith A, Chen, Ying, Davis, Craig B, Huang, Bo, Fly, Kolette D, Thall, Aron, Woolfson, Adrian, Bartlett, Nancy L
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SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy
Drilon, Alexander, Sharma, Manish R, Johnson, Melissa L, Yap, Timothy A, Gadgeel, Shirish, Nepert, Dale, Feng, Gang, Reddy, Micaela B, Harney, Allison S, Elsayed, Mohamed, Cook, Adam W, Wong, Christina E, Hinklin, Ronald J, Jiang, Yutong, Brown, Eric N, Neitzel, Nickolas A, Laird, Ellen R, Wu, Wen-I, Singh, Anurag, Wei, Ping, Ching, Keith A, Gaudino, John J, Lee, Patrice A, Hartley, Dylan P, Rothenberg, S Michael
Published in Cancer discovery (04.08.2023)
Published in Cancer discovery (04.08.2023)
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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
Xu, Yuanming, Carrascosa, Lucia Campos, Yeung, Yik Andy, Chu, Matthew Ling-Hon, Yang, Wenjing, Djuretic, Ivana, Pappas, Danielle C, Zeytounian, John, Ge, Zhouhong, de Ruiter, Valeska, Starbeck-Miller, Gabriel R, Patterson, James, Rigas, Diamanda, Chen, Shih-Hsun, Kraynov, Eugenia, Boor, Patrick P, Noordam, Lisanne, Doukas, Michael, Tsao, Dave, Ijzermans, Jan N, Guo, Jie, Grünhagen, Dirk J, Erdmann, Joris, Verheij, Joanne, van Royen, Martin E, Doornebosch, Pascal G, Feldman, Renny, Park, Terrence, Mahmoudi, Salah, Dorywalska, Magdalena, Ni, Irene, Chin, Sherman M, Mistry, Tina, Mosyak, Lidia, Lin, Laura, Ching, Keith A, Lindquist, Kevin C, Ji, Changhua, Londono, Luz Marina, Kuang, Bing, Rickert, Robert, Kwekkeboom, Jaap, Sprengers, Dave, Huang, Tzu-Hsuan, Chaparro-Riggers, Javier
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Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer
Nam, Hyun-Jin, Ching, Keith A, Kan, Julie, Kim, Hwang-Phill, Han, Sae-Won, Im, Seock-Ah, Kim, Tae-You, Christensen, James G, Oh, Do-Youn, Bang, Yung-Jue
Published in Molecular cancer therapeutics (01.02.2012)
Published in Molecular cancer therapeutics (01.02.2012)
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Molecular predictors of sensitivity to the insulin-like growth factor 1 receptor inhibitor Figitumumab (CP-751,871)
Pavlicek, Adam, Lira, Maruja E, Lee, Nathan V, Ching, Keith A, Ye, Jingjing, Cao, Joan, Garza, Scott J, Hook, Kenneth E, Ozeck, Mark, Shi, Stephanie T, Yuan, Jing, Zheng, Xianxian, Rejto, Paul A, Kan, Julie L C, Christensen, James G
Published in Molecular cancer therapeutics (01.12.2013)
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Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma
Diamond, Jennifer R, Salgia, Ravi, Varella-Garcia, Marileila, Kanteti, Rajani, LoRusso, Patricia M, Clark, Jeffrey W, Xu, Ling-Guo, Wilner, Keith, Eckhardt, S Gail, Ching, Keith A, Lira, Maruja E, Schoenmakers, Eric F P M, Christensen, James G, Camidge, D Ross
Published in Journal of clinical oncology (01.06.2013)
Published in Journal of clinical oncology (01.06.2013)
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