Ketone bodies: A double‐edged sword for mammalian life span
Tomita, Issei, Tsuruta, Hiroaki, Yasuda‐Yamahara, Mako, Yamahara, Kosuke, Kuwagata, Shogo, Tanaka‐Sasaki, Yuki, Chin‐Kanasaki, Masami, Fujita, Yukihiro, Nishi, Eiichiro, Katagiri, Hideki, Maegawa, Hiroshi, Kume, Shinji
Published in Aging cell (01.06.2023)
Published in Aging cell (01.06.2023)
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Journal Article
Role of dietary amino acid balance in diet restriction‐mediated lifespan extension, renoprotection, and muscle weakness in aged mice
Yoshida, Shohei, Yamahara, Kosuke, Kume, Shinji, Koya, Daisuke, Yasuda‐Yamahara, Mako, Takeda, Naoko, Osawa, Norihisa, Chin‐Kanasaki, Masami, Adachi, Yusuke, Nagao, Kenji, Maegawa, Hiroshi, Araki, Shin‐ichi
Published in Aging cell (01.08.2018)
Published in Aging cell (01.08.2018)
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Journal Article
Improvement in Decline Rate of Estimated Glomerular Filtration Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria
Kume, Shinji, Yasuda-Yamahara, Mako, Imamura-Uehara, Yoshimi, Kuwagata, Shogo, Yamahara, Kosuke, Takeda, Naoko, Chin-Kanasaki, Masami, Kato, Koichi, Ohno, Seiko, Nakagawa, Yoshihisa, Maegawa, Hiroshi
Published in Internal Medicine (15.10.2022)
Published in Internal Medicine (15.10.2022)
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Journal Article
Impact of obesity on annual medical expenditures and diabetes care in Japanese patients with type 2 diabetes mellitus
Kusunoki‐Tsuji, Chisato, Araki, Shin‐ichi, Kume, Shinji, Chin‐Kanasaki, Masami, Osawa, Norihisa, Morino, Katsutaro, Sekine, Osamu, Ugi, Satoshi, Kashiwagi, Atsunori, Maegawa, Hiroshi
Published in Journal of diabetes investigation (01.07.2018)
Published in Journal of diabetes investigation (01.07.2018)
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Journal Article
SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition
Tomita, Issei, Kume, Shinji, Sugahara, Sho, Osawa, Norihisa, Yamahara, Kosuke, Yasuda-Yamahara, Mako, Takeda, Naoko, Chin-Kanasaki, Masami, Kaneko, Tatsuroh, Mayoux, Eric, Mark, Michael, Yanagita, Motoko, Ogita, Hisakazu, Araki, Shin-ichi, Maegawa, Hiroshi
Published in Cell metabolism (01.09.2020)
Published in Cell metabolism (01.09.2020)
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Journal Article
Contrast medium-induced severe thrombocytopenia in patient on maintenance hemodialysis: a case report and literature review
Takeda, Naoko, Araki, Shin-ichi, Chin-Kanasaki, Masami, Osawa, Norihisa, Sawai, Kazunobu, Yamahara, Kousuke, Yasuda-Yamahara, Mako, Kume, Shinji, Fujita, Yukihiro, Maegawa, Hiroshi
Published in CEN case reports (01.08.2020)
Published in CEN case reports (01.08.2020)
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Journal Article
Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy
Tagawa, Atsuko, Yasuda, Mako, Kume, Shinji, Yamahara, Kosuke, Nakazawa, Jun, Chin-Kanasaki, Masami, Araki, Hisazumi, Araki, Shin-Ichi, Koya, Daisuke, Asanuma, Katsuhiko, Kim, Eun-Hee, Haneda, Masakazu, Kajiwara, Nobuyuki, Hayashi, Kazuyuki, Ohashi, Hiroshi, Ugi, Satoshi, Maegawa, Hiroshi, Uzu, Takashi
Published in Diabetes (New York, N.Y.) (01.03.2016)
Published in Diabetes (New York, N.Y.) (01.03.2016)
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Journal Article
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
Kume, Shinji, Uzu, Takashi, Horiike, Kihachiro, Chin-Kanasaki, Masami, Isshiki, Keiji, Araki, Shin-Ichi, Sugimoto, Toshiro, Haneda, Masakazu, Kashiwagi, Atsunori, Koya, Daisuke
Published in The Journal of clinical investigation (01.04.2010)
Published in The Journal of clinical investigation (01.04.2010)
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Journal Article
Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions
YAMAHARA, Kosuke, KUME, Shinji, MATSUSAKA, Taiji, KASHIWAGI, Atsunori, MAEGAWA, Hiroshi, UZU, Takashi, KOYA, Daisuke, TANAKA, Yuki, MORITA, Yoshikata, CHIN-KANASAKI, Masami, ARAKI, Hisazumi, ISSHIKI, Keiji, ARAKI, Shin-Ichi, HANEDA, Masakazu
Published in Journal of the American Society of Nephrology (01.11.2013)
Published in Journal of the American Society of Nephrology (01.11.2013)
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Journal Article
Focal Segmental Glomerular Sclerosis Ameliorated by Long-term Hemodialysis Therapy with Low-density Lipoprotein Apheresis
Araki, Hisazumi, Ono, Shinya, Nishizawa, Yuka, Deji, Naoko, Nakazawa, Jun, Morita, Yoshikata, Kume, Shinji, Chin-Kanasaki, Masami, Isshiki, Keiji, Araki, Shin-ichi, Arimura, Tetsuro, Maegawa, Hiroshi, Uzu, Takashi
Published in Internal Medicine (01.01.2015)
Published in Internal Medicine (01.01.2015)
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Journal Article
Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes
Yasuda, Mako, Tanaka, Yuki, Kume, Shinji, Morita, Yoshikata, Chin-Kanasaki, Masami, Araki, Hisazumi, Isshiki, Keiji, Araki, Shin-ichi, Koya, Daisuke, Haneda, Masakazu, Kashiwagi, Atsunori, Maegawa, Hiroshi, Uzu, Takashi
Published in Biochimica et biophysica acta (01.07.2014)
Published in Biochimica et biophysica acta (01.07.2014)
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Journal Article
Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia-reperfusion-induced acute kidney injury
NAKAZAWA, JUN, ISSHIKI, KEIJI, SUGIMOTO, TOSHIRO, ARAKI, SHIN-ICHI, KUME, SHINJI, YOKOMAKU, YUKIYO, CHIN-KANASAKI, MASAMI, SAKAGUCHI, MASAYOSHI, KOYA, DAISUKE, HANEDA, MASAKAZU, KASHIWAGI, ATSUNORI, UZU, TAKASHI
Published in Nephrology (Carlton, Vic.) (01.02.2010)
Published in Nephrology (Carlton, Vic.) (01.02.2010)
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Journal Article
Inhibition of mitochondrial fission protects podocytes from albumin-induced cell damage in diabetic kidney disease
Tagaya, Makoto, Kume, Shinji, Yasuda-Yamahara, Mako, Kuwagata, Shogo, Yamahara, Kosuke, Takeda, Naoko, Tanaka, Yuki, Chin-Kanasaki, Masami, Nakae, Yuki, Yokoi, Hideki, Mukoyama, Masashi, Ishihara, Naotada, Nomura, Masatoshi, Araki, Shin-ichi, Maegawa, Hiroshi
Published in Biochimica et biophysica acta. Molecular basis of disease (01.05.2022)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.05.2022)
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Journal Article
Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes
Sugahara, Sho, Kume, Shinji, Chin-Kanasaki, Masami, Tomita, Issei, Yasuda-Yamahara, Mako, Yamahara, Kosuke, Takeda, Naoko, Osawa, Norihisa, Yanagita, Motoko, Araki, Shin-Ichi, Maegawa, Hiroshi
Published in Journal of the American Society of Nephrology (01.06.2019)
Published in Journal of the American Society of Nephrology (01.06.2019)
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Journal Article
Structural and functional changes in the kidneys of high-fat diet-induced obese mice
Deji, Naoko, Kume, Shinji, Araki, Shin-Ichi, Soumura, Mariko, Sugimoto, Toshiro, Isshiki, Keiji, Chin-Kanasaki, Masami, Sakaguchi, Masayoshi, Koya, Daisuke, Haneda, Masakazu, Kashiwagi, Atsunori, Uzu, Takashi
Published in American journal of physiology. Renal physiology (01.01.2009)
Published in American journal of physiology. Renal physiology (01.01.2009)
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Journal Article
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells
Koyama, Tetsuro, Kume, Shinji, Koya, Daisuke, Araki, Shin-ichi, Isshiki, Keiji, Chin-Kanasaki, Masami, Sugimoto, Toshiro, Haneda, Masakazu, Sugaya, Takeshi, Kashiwagi, Atsunori, Maegawa, Hiroshi, Uzu, Takashi
Published in Free radical biology & medicine (15.09.2011)
Published in Free radical biology & medicine (15.09.2011)
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Journal Article
1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells
Tanaka, Yuki, Kume, Shinji, Araki, Hisazumi, Nakazawa, Jun, Chin-Kanasaki, Masami, Araki, Shin-ichi, Nakagawa, Fumiyuki, Koya, Daisuke, Haneda, Masakazu, Maegawa, Hiroshi, Uzu, Takashi
Published in Free radical biology & medicine (01.12.2015)
Published in Free radical biology & medicine (01.12.2015)
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Journal Article
Limited effects of systemic or renal lipoprotein lipase deficiency on renal physiology and diseases
Fujino, Yoshihiko, Yasuda-Yamahara, Mako, Tanaka-Sasaki, Yuki, Kuwagata, Shogo, Yamahara, Kosuke, Tagawa, Atsuko, Chin-Kanasaki, Masami, Yanagita, Motoko, Maegawa, Hiroshi, Kume, Shinji
Published in Biochemical and biophysical research communications (10.09.2022)
Published in Biochemical and biophysical research communications (10.09.2022)
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Journal Article
Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet
KUME, Shinji, UZU, Takashi, HANEDA, Masakazu, KASHIWAGI, Atsunori, KOYA, Daisuke, ARAKI, Shin-Ichi, SUGIMOTO, Toshiro, ISSHIKI, Keiji, CHIN-KANASAKI, Masami, SAKAGUCHI, Masayoshi, KUBOTA, Naoto, TERAUCHI, Yasuo, KADOWAKI, Takashi
Published in Journal of the American Society of Nephrology (01.10.2007)
Published in Journal of the American Society of Nephrology (01.10.2007)
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Journal Article
Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury
Tanaka, Yuki, Kume, Shinji, Chin-Kanasaki, Masami, Araki, Hisazumi, Araki, Shin-ichi, Ugi, Satoshi, Sugaya, Takeshi, Uzu, Takashi, Maegawa, Hiroshi
Published in Biochemical and biophysical research communications (12.02.2016)
Published in Biochemical and biophysical research communications (12.02.2016)
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