A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
Chin, Willy, Zhong, Guansheng, Pu, Qinqin, Yang, Chuan, Lou, Weiyang, De Sessions, Paola Florez, Periaswamy, Balamurugan, Lee, Ashlynn, Liang, Zhen Chang, Ding, Xin, Gao, Shujun, Chu, Collins Wenhan, Bianco, Simone, Bao, Chang, Tong, Yen Wah, Fan, Weimin, Wu, Min, Hedrick, James L., Yang, Yi Yan
Published in Nature communications (02.03.2018)
Published in Nature communications (02.03.2018)
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Journal Article
Biodegradable Broad-Spectrum Antimicrobial Polycarbonates: Investigating the Role of Chemical Structure on Activity and Selectivity
Chin, Willy, Yang, Chuan, Ng, Victor Wee Lin, Huang, Yuan, Cheng, Junchi, Tong, Yen Wah, Coady, Daniel J, Fan, Weimin, Hedrick, James L, Yang, Yi Yan
Published in Macromolecules (26.11.2013)
Published in Macromolecules (26.11.2013)
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Journal Article
Benzyl Chloride-Functionalized Polycarbonates: A Versatile Platform for the Synthesis of Functional Biodegradable Polycarbonates
Ono, Robert J, Liu, Shao Qiong, Venkataraman, Shrinivas, Chin, Willy, Yang, Yi Yan, Hedrick, James L
Published in Macromolecules (25.11.2014)
Published in Macromolecules (25.11.2014)
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Journal Article
Pentanidium–Catalyzed Enantioselective α‑Hydroxylation of Oxindoles Using Molecular Oxygen
Yang, Yuanyong, Moinodeen, Farhana, Chin, Willy, Ma, Ting, Jiang, Zhiyong, Tan, Choon-Hong
Published in Organic letters (21.09.2012)
Published in Organic letters (21.09.2012)
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Journal Article
Injectable Coacervate Hydrogel for Delivery of Anticancer Drug-Loaded Nanoparticles in vivo
Lee, Ashlynn L. Z, Voo, Zhi Xiang, Chin, Willy, Ono, Robert J, Yang, Chuan, Gao, Shujun, Hedrick, James L, Yang, Yi Yan
Published in ACS applied materials & interfaces (25.04.2018)
Published in ACS applied materials & interfaces (25.04.2018)
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Journal Article
Disease-directed design of biodegradable polymers: Reactive oxygen species and pH-responsive micellar nanoparticles for anticancer drug delivery
Leong, Jiayu, Chin, Willy, Ke, Xiyu, Gao, Shujun, Kong, Hyunjoon, Hedrick, James L., Yang, Yi Yan
Published in Nanomedicine (01.11.2018)
Published in Nanomedicine (01.11.2018)
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Journal Article
pH and redox dual-responsive biodegradable polymeric micelles with high drug loading for effective anticancer drug delivery
Teo, Jye Yng, Chin, Willy, Ke, Xiyu, Gao, Shujun, Liu, Shaoqiong, Cheng, Wei, Hedrick, James L, Yang, Yin Yan
Published in Nanomedicine (01.02.2017)
Published in Nanomedicine (01.02.2017)
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Journal Article
Degradable antimicrobial polycarbonates with unexpected activity and selectivity for treating multidrug-resistant Klebsiella pneumoniae lung infection in mice
Yang, Chuan, Lou, Weiyang, Zhong, Guansheng, Lee, Ashlynn, Leong, Jiayu, Chin, Willy, Ding, Bisha, Bao, Chang, Tan, Jeremy P.K., Pu, Qinqin, Gao, Shujun, Xu, Liang, Hsu, Li Yang, Wu, Min, Hedrick, James L., Fan, Weimin, Yang, Yi Yan
Published in Acta biomaterialia (01.08.2019)
Published in Acta biomaterialia (01.08.2019)
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Journal Article
Developments in Dynamic Covalent Chemistries from the Reaction of Thiols with Hexahydrotriazines
Wojtecki, Rudy J, Jones, Gavin O, Yuen, Alexander Y, Chin, Willy, Boday, Dylan J, Nelson, Alshakim, García, Jeannette M, Yang, Yi Yan, Hedrick, James L
Published in Journal of the American Chemical Society (18.11.2015)
Published in Journal of the American Chemical Society (18.11.2015)
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Journal Article
Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug-Resistant MRSA Systemic Infection
Cheng, Junchi, Chin, Willy, Dong, Huihui, Xu, Liang, Zhong, Guansheng, Huang, Yuan, Li, Lanjuan, Xu, Kaijin, Wu, Min, Hedrick, James L, Yang, Yi Yan, Fan, Weimin
Published in Advanced healthcare materials (01.10.2015)
Published in Advanced healthcare materials (01.10.2015)
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Journal Article
Enhancement of cationic antimicrobial materials via cholesterol incorporation
Coady, Daniel J, Ong, Zhan Yuin, Lee, Pei Shan, Venkataraman, Shrinivas, Chin, Willy, Engler, Amanda C, Yang, Yi Yan, Hedrick, James L
Published in Advanced healthcare materials (01.06.2014)
Published in Advanced healthcare materials (01.06.2014)
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Journal Article
Biodegradable Block Copolyelectrolyte Hydrogels for Tunable Release of Therapeutics and Topical Antimicrobial Skin Treatment
Ono, Robert J., Lee, Ashlynn L. Z., Chin, Willy, Goh, Wei Sheng, Lee, Amelia Y. L., Yang, Yi Yan, Hedrick, James L.
Published in ACS macro letters (15.09.2015)
Published in ACS macro letters (15.09.2015)
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Journal Article
ANTIMICROBIAL CATIONIC POLYCARBONATE
DANIEL JOSEPH COADY, AMANDA CATHERINE ENGLER, CHIN WILLY, ONG ZHAN-YUIN, JAMES LUPTON HEDRICK, RICHARD ANTHONY DIPIETRO, ASHLYNN L Z LEE, VICTOR W L NG, YANG YI YAN
Year of Publication 10.05.2018
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Year of Publication 10.05.2018
Patent
Star polymers with enhanced antimicrobial activity in response to light
Yang, Yi Yan, Chin, Willy, Voo, Zhi Xiang, Fine Nathel, Noah Frederick, Hedrick, James L, Piunova, Victoria A
Year of Publication 19.03.2024
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Year of Publication 19.03.2024
Patent
Antimicrobial guanidinium and thiouronium functionalized polymers
Chin, Willy, Yang, Yi Yan, Lee, Ashlynn L. Z, Ibrahim, Nor Lizawati, Hedrick, James L, Ono, Robert J, Xu, Qingxing
Year of Publication 04.07.2023
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Year of Publication 04.07.2023
Patent
Star polymers with enhanced antimicrobial activity in response to light
Zhi Xiang Voo, Noah Frederick Fine Nathel, Victoria Piunova, James Hedrick, Willy Chin, Yi Yan Yang
Year of Publication 16.12.2020
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Year of Publication 16.12.2020
Patent
Block copolymers and self-assembling nanoparticles formed therefrom
Eunice Leong, Dylan Boday, Nathaniel Park, James Hedrick, Rudy J Wojtecki, Willy Chin, Mareva Fevre, Jeannette M Garcia, Yi Yan Yang
Year of Publication 08.06.2022
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Year of Publication 08.06.2022
Patent
Star polymers with enhanced antimicrobial activity in response to light
Zhi Xiang Voo, Noah Frederick Fine Nathel, Victoria Piunova, James Hedrick, Willy Chin, Yi Yan Yang
Year of Publication 15.07.2020
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Year of Publication 15.07.2020
Patent