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Davidson, Shawn M., Papagiannakopoulos, Thales, Olenchock, Benjamin A., Heyman, Julia E., Keibler, Mark A., Luengo, Alba, Bauer, Matthew R., Jha, Abhishek K., O’Brien, James P., Pierce, Kerry A., Gui, Dan Y., Sullivan, Lucas B., Wasylenko, Thomas M., Subbaraj, Lakshmipriya, Chin, Christopher R., Stephanopolous, Gregory, Mott, Bryan T., Jacks, Tyler, Clish, Clary B., Vander Heiden, Matthew G.
Published in Cell metabolism (08.03.2016)
Published in Cell metabolism (08.03.2016)
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Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
Davidson, Shawn M, Jonas, Oliver, Keibler, Mark A, Hou, Han Wei, Luengo, Alba, Mayers, Jared R, Wyckoff, Jeffrey, Del Rosario, Amanda M, Whitman, Matthew, Chin, Christopher R, Condon, Kendall J, Lammers, Alex, Kellersberger, Katherine A, Stall, Brian K, Stephanopoulos, Gregory, Bar-Sagi, Dafna, Han, Jongyoon, Rabinowitz, Joshua D, Cima, Michael J, Langer, Robert, Vander Heiden, Matthew G
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IFITMs Restrict the Replication of Multiple Pathogenic Viruses
Perreira, Jill M., Chin, Christopher R., Feeley, Eric M., Brass, Abraham L.
Published in Journal of molecular biology (13.12.2013)
Published in Journal of molecular biology (13.12.2013)
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Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration
Chin, Christopher R., Perreira, Jill M., Savidis, George, Portmann, Jocelyn M., Aker, Aaron M., Feeley, Eric M., Smith, Miles C., Brass, Abraham L.
Published in Cell reports (Cambridge) (24.11.2015)
Published in Cell reports (Cambridge) (24.11.2015)
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Reactivation of Latent HIV-1 by Inhibition of BRD4
Zhu, Jian, Gaiha, Gaurav D., John, Sinu P., Pertel, Thomas, Chin, Christopher R., Gao, Geng, Qu, Hongjing, Walker, Bruce D., Elledge, Stephen J., Brass, Abraham L.
Published in Cell reports (Cambridge) (25.10.2012)
Published in Cell reports (Cambridge) (25.10.2012)
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IFITM3 inhibits influenza A virus infection by preventing cytosolic entry
Feeley, Eric M, Sims, Jennifer S, John, Sinu P, Chin, Christopher R, Pertel, Thomas, Chen, Li-Mei, Gaiha, Gaurav D, Ryan, Bethany J, Donis, Ruben O, Elledge, Stephen J, Brass, Abraham L
Published in PLoS pathogens (01.10.2011)
Published in PLoS pathogens (01.10.2011)
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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
Venturutti, Leandro, Teater, Matt, Zhai, Andrew, Chadburn, Amy, Babiker, Leena, Kim, Daleum, Béguelin, Wendy, Lee, Tak C., Kim, Youngjun, Chin, Christopher R., Yewdell, William T., Raught, Brian, Phillip, Jude M., Jiang, Yanwen, Staudt, Louis M., Green, Michael R., Chaudhuri, Jayanta, Elemento, Olivier, Farinha, Pedro, Weng, Andrew P., Nissen, Michael D., Steidl, Christian, Morin, Ryan D., Scott, David W., Privé, Gilbert G., Melnick, Ari M.
Published in Cell (23.07.2020)
Published in Cell (23.07.2020)
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Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity
Gertz, Monica L., Chin, Christopher R., Tomoiaga, Delia, MacKay, Matthew, Chang, Christina, Butler, Daniel, Afshinnekoo, Ebrahim, Bezdan, Daniela, Schmidt, Michael A., Mozsary, Christopher, Melnick, Ari, Garrett-Bakelman, Francine, Crucian, Brian, Lee, Stuart M.C., Zwart, Sara R., Smith, Scott M., Meydan, Cem, Mason, Christopher E.
Published in Cell reports (Cambridge) (08.12.2020)
Published in Cell reports (Cambridge) (08.12.2020)
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Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Kim, JangKeun, Tierney, Braden T., Overbey, Eliah G., Dantas, Ezequiel, Fuentealba, Matias, Park, Jiwoon, Narayanan, S. Anand, Wu, Fei, Najjar, Deena, Chin, Christopher R., Meydan, Cem, Loy, Conor, Mathyk, Begum, Klotz, Remi, Ortiz, Veronica, Nguyen, Khiem, Ryon, Krista A., Damle, Namita, Houerbi, Nadia, Patras, Laura I., Schanzer, Nathan, Hutchinson, Gwyneth A., Foox, Jonathan, Bhattacharya, Chandrima, Mackay, Matthew, Afshin, Evan E., Hirschberg, Jeremy Wain, Kleinman, Ashley S., Schmidt, Julian C., Schmidt, Caleb M., Schmidt, Michael A., Beheshti, Afshin, Matei, Irina, Lyden, David, Mullane, Sean, Asadi, Amran, Lenz, Joan S., Mzava, Omary, Yu, Min, Ganesan, Saravanan, De Vlaminck, Iwijn, Melnick, Ari M., Barisic, Darko, Winer, Daniel A., Zwart, Sara R., Crucian, Brian E., Smith, Scott M., Mateus, Jaime, Furman, David, Mason, Christopher E.
Published in Nature communications (11.06.2024)
Published in Nature communications (11.06.2024)
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The CD225 Domain of IFITM3 Is Required for both IFITM Protein Association and Inhibition of Influenza A Virus and Dengue Virus Replication
John, Sinu P, Chin, Christopher R, Perreira, Jill M, Feeley, Eric M, Aker, Aaron M, Savidis, George, Smith, Sarah E, Elia, Andrew E H, Everitt, Aaron R, Vora, Mehul, Pertel, Thomas, Elledge, Stephen J, Kellam, Paul, Brass, Abraham L
Published in Journal of Virology (01.07.2013)
Published in Journal of Virology (01.07.2013)
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Dysfunctional HIV-Specific CD8+ T Cell Proliferation Is Associated with Increased Caspase-8 Activity and Mediated by Necroptosis
Gaiha, Gaurav D., McKim, Kevin J., Woods, Matthew, Pertel, Thomas, Rohrbach, Janine, Barteneva, Natasha, Chin, Christopher R., Liu, Dongfang, Soghoian, Damien Z., Cesa, Kevin, Wilton, Shannon, Waring, Michael T., Chicoine, Adam, Doering, Travis, Wherry, E. John, Kaufmann, Daniel E., Lichterfeld, Mathias, Brass, Abraham L., Walker, Bruce D.
Published in Immunity (Cambridge, Mass.) (18.12.2014)
Published in Immunity (Cambridge, Mass.) (18.12.2014)
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HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells
Nguyen, Diu T. T., Lu, Yuheng, Chu, Eren L., Yang, Xuejing, Park, Sun-Mi, Choo, Zi-Ning, Chin, Christopher R., Prieto, Camila, Schurer, Alexandra, Barin, Ersilia, Savino, Angela M., Gourkanti, Saroj, Patel, Payal, Vu, Ly P., Leslie, Christina S., Kharas, Michael G.
Published in Nature communications (24.04.2020)
Published in Nature communications (24.04.2020)
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Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
Lau, Allison N, Li, Zhaoqi, Danai, Laura V, Westermark, Anna M, Darnell, Alicia M, Ferreira, Raphael, Gocheva, Vasilena, Sivanand, Sharanya, Lien, Evan C, Sapp, Kiera M, Mayers, Jared R, Biffi, Giulia, Chin, Christopher R, Davidson, Shawn M, Tuveson, David A, Jacks, Tyler, Matheson, Nicholas J, Yilmaz, Omer, Vander Heiden, Matthew G
Published in eLife (10.07.2020)
Published in eLife (10.07.2020)
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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
Hamza, Bashar, Miller, Alex B., Meier, Lara, Stockslager, Max, Ng, Sheng Rong, King, Emily M., Lin, Lin, DeGouveia, Kelsey L., Mulugeta, Nolawit, Calistri, Nicholas L., Strouf, Haley, Bray, Christina, Rodriguez, Felicia, Freed-Pastor, William A., Chin, Christopher R., Jaramillo, Grissel C., Burger, Megan L., Weinberg, Robert A., Shalek, Alex K., Jacks, Tyler, Manalis, Scott R.
Published in Nature communications (28.09.2021)
Published in Nature communications (28.09.2021)
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ChromaFold predicts the 3D contact map from single-cell chromatin accessibility
Gao, Vianne R., Yang, Rui, Das, Arnav, Luo, Renhe, Luo, Hanzhi, McNally, Dylan R., Karagiannidis, Ioannis, Rivas, Martin A., Wang, Zhong-Min, Barisic, Darko, Karbalayghareh, Alireza, Wong, Wilfred, Zhan, Yingqian A., Chin, Christopher R., Noble, William S., Bilmes, Jeff A., Apostolou, Effie, Kharas, Michael G., Béguelin, Wendy, Viny, Aaron D., Huangfu, Danwei, Rudensky, Alexander Y., Melnick, Ari M., Leslie, Christina S.
Published in Nature communications (01.11.2024)
Published in Nature communications (01.11.2024)
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Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development
Malkani, Sherina, Chin, Christopher R., Cekanaviciute, Egle, Mortreux, Marie, Okinula, Hazeem, Tarbier, Marcel, Schreurs, Ann-Sofie, Shirazi-Fard, Yasaman, Tahimic, Candice G.T., Rodriguez, Deyra N., Sexton, Brittany S., Butler, Daniel, Verma, Akanksha, Bezdan, Daniela, Durmaz, Ceyda, MacKay, Matthew, Melnick, Ari, Meydan, Cem, Li, Sheng, Garrett-Bakelman, Francine, Fromm, Bastian, Afshinnekoo, Ebrahim, Langhorst, Brad W., Dimalanta, Eileen T., Cheng-Campbell, Margareth, Blaber, Elizabeth, Schisler, Jonathan C., Vanderburg, Charles, Friedländer, Marc R., McDonald, J. Tyson, Costes, Sylvain V., Rutkove, Seward, Grabham, Peter, Mason, Christopher E., Beheshti, Afshin
Published in Cell reports (Cambridge) (08.12.2020)
Published in Cell reports (Cambridge) (08.12.2020)
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Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction
Lin, Tsai-Yu, Chin, Christopher R., Everitt, Aaron R., Clare, Simon, Perreira, Jill M., Savidis, George, Aker, Aaron M., John, Sinu P., Sarlah, David, Carreira, Erick M., Elledge, Stephen J., Kellam, Paul, Brass, Abraham L.
Published in Cell reports (Cambridge) (27.11.2013)
Published in Cell reports (Cambridge) (27.11.2013)
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Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment
Li, Jie, Chin, Christopher R., Ying, Hsia-Yuan, Meydan, Cem, Teater, Matthew R., Xia, Min, Farinha, Pedro, Takata, Katsuyoshi, Chu, Chi-Shuen, Jiang, Yiyue, Eagles, Jenna, Passerini, Verena, Tang, Zhanyun, Rivas, Martin A., Weigert, Oliver, Pugh, Trevor J., Chadburn, Amy, Steidl, Christian, Scott, David W., Roeder, Robert G., Mason, Christopher E., Zappasodi, Roberta, Béguelin, Wendy, Melnick, Ari M.
Published in Nature communications (03.04.2024)
Published in Nature communications (03.04.2024)
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RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus
Perreira, Jill M., Aker, Aaron M., Savidis, George, Chin, Christopher R., McDougall, William M., Portmann, Jocelyn M., Meraner, Paul, Smith, Miles C., Rahman, Motiur, Baker, Richard E., Gauthier, Annick, Franti, Michael, Brass, Abraham L.
Published in Cell reports (Cambridge) (04.08.2015)
Published in Cell reports (Cambridge) (04.08.2015)
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