Search Results - "Childers, Matthew C." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

by Landim-Vieira, Maicon, Childers, Matthew C, Wacker, Amanda L, Garcia, Michelle Rodriquez, He, Huan, Singh, Rakesh, Brundage, Elizabeth A, Johnston, Jamie R, Whitson, Bryan A, Chase, P Bryant, Janssen, Paul M L, Regnier, Michael, Biesiadecki, Brandon J, Pinto, J Renato, Parvatiyar, Michelle S
Published in eLife (03.05.2022)

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Edge Strand Dissociation and Conformational Changes in Transthyretin under Amyloidogenic Conditions

Edge Strand Dissociation and Conformational Changes in Transthyretin under Amyloidogenic Conditions

by Childers, Matthew C., Daggett, Valerie
Published in Biophysical journal (17.11.2020)

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Journal Article

Using 2’-deoxy-ADP to probe stability of the myosin interacting heads motif at atomic resolution

Using 2’-deoxy-ADP to probe stability of the myosin interacting heads motif at atomic resolution

by Childers, Matthew C., Regnier, Michael
Published in Biophysical journal (10.02.2023)

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Journal Article

The β-myosin G256E mutation impairs relaxation by altering transducer stiffness

The β-myosin G256E mutation impairs relaxation by altering transducer stiffness

by Childers, Matthew C., Kao, Kerry Y., Mohran, Saffie, Regnier, Michael
Published in Biophysical journal (10.02.2023)

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Journal Article

Conserved patterns and interactions in the unfolding transition state across SH3 domain structural homologues

Conserved patterns and interactions in the unfolding transition state across SH3 domain structural homologues

by Demakis, Cullen, Childers, Matthew C., Daggett, Valerie
Published in Protein science (01.02.2021)

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Journal Article

Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin

Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin

by Rynkiewicz, Michael J, Childers, Matthew C, Karpicheva, Olga E, Regnier, Michael, Geeves, Michael A, Lehman, William
Published in The Journal of general physiology (06.05.2024)

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Journal Article

A molecular scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation

A molecular scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation

by Kao, Kerry Y., Childers, Matthew C., Mohran, Saffie, Geeves, Michael A., Regnier, Michael
Published in Biophysical journal (10.02.2023)

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Characterizing the functional impact of embryonic myosin mutations in stem cell-derived skeletal muscle

Characterizing the functional impact of embryonic myosin mutations in stem cell-derived skeletal muscle

by Mandrycky, Christian, Mohran, Saffie, Childers, Matthew C., Smith, Alec S.T., Regnier, Michael, Mack, David L.
Published in Biophysical journal (10.02.2023)

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Embryonic myosin mutations alter the mechanics and maturation of HiPSC derived skeletal muscle

Embryonic myosin mutations alter the mechanics and maturation of HiPSC derived skeletal muscle

by Mandrycky, Christian J., Mohran, Saffie, Childers, Matthew C., Luttrell, Shawn M., Buckingham, Kati, Bamshad, Michael J., Mack, David L., Regnier, Michael
Published in Biophysical journal (10.02.2023)

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Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration

Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration

by Lee, Soah, Vander Roest, Alison S, Blair, Cheavar A, Kao, Kerry, Bremner, Samantha B, Childers, Matthew C, Pathak, Divya, Heinrich, Paul, Lee, Daniel, Chirikian, Orlando, Mohran, Saffie E, Roberts, Brock, Smith, Jacqueline E, Jahng, James W, Paik, David T, Wu, Joseph C, Gunawardane, Ruwanthi N, Ruppel, Kathleen M, Mack, David L, Pruitt, Beth L, Regnier, Michael, Wu, Sean M, Spudich, James A, Bernstein, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (07.05.2024)

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Putting the oh-my! in myosin: using 2'-deoxy-adp and omecamtiv mecarbil to identify new strategies for engineering myosin contractility

Putting the oh-my! in myosin: using 2'-deoxy-adp and omecamtiv mecarbil to identify new strategies for engineering myosin contractility

by Childers, Matthew C., Regnier, Michael
Published in Biophysical journal (11.02.2022)

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A molecular-scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation

A molecular-scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation

by Kao, Kerry Y., Childers, Matthew C., Mohran, Saffie, Regnier, Michael
Published in Biophysical journal (08.02.2024)

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Journal Article

Drivers of Conformational Variability in Transthyretin Monomers under Amyloidogenic Conditions

Drivers of Conformational Variability in Transthyretin Monomers under Amyloidogenic Conditions

by Childers, Matthew C., Daggett, Valerie
Published in Biophysical journal (02.02.2018)

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Journal Article

Nucleotide-Dependent Allosteric Communication in Myosin

Nucleotide-Dependent Allosteric Communication in Myosin

by Childers, Matthew C., Daggett, Valerie, Regnier, Michael
Published in Biophysical journal (07.02.2020)

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Journal Article

Cross-Species Dynamics of Myosin in Pre-Powerstroke States

Cross-Species Dynamics of Myosin in Pre-Powerstroke States

by Childers, Matthew C., Daggett, Valerie, Regnier, Michael
Published in Biophysical journal (07.02.2020)

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Journal Article

Mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation studied using CRISPR-edited hiPSC-CMs

Mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation studied using CRISPR-edited hiPSC-CMs

by Kao, Kerry Y., Childers, Matthew C., Mohran, Saffie, Regnier, Michael
Published in Biophysical journal (11.02.2022)

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A molecular dynamics investigation of the dysfunction of the dilated cardiomyopathy-associated MYH7 mutation R369Q

A molecular dynamics investigation of the dysfunction of the dilated cardiomyopathy-associated MYH7 mutation R369Q

by Prabhala, Aditi M., Childers, Matthew C., Kao, Kerry Y., Regnier, Michael
Published in Biophysical journal (08.02.2024)

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Journal Article

Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin

Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin

by Lehman, William, Childers, Matthew C., Regnier, Michael, Geeves, Michael A., Rynkiewicz, Michael J.
Published in Biophysical journal (08.02.2024)

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Journal Article

Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations

Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations

by Malingen, Sage, Childers, Matthew C., Tune, Travis, Kao, Kerry Y., Daniel, Thomas L., Moussavi-Harami, Farid, Regnier, Michael
Published in Biophysical journal (08.02.2024)

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Structural effects of disease associated mutations on pre-powerstroke myosin

Structural effects of disease associated mutations on pre-powerstroke myosin

by Childers, Matthew C., Hock, Marcus, Teitgen, Abigail E., McCulloch, Andrew D., Regnier, Michael
Published in Biophysical journal (11.02.2022)

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