Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes
Gan, Li-Ming, Lagerström-Fermér, Maria, Carlsson, Leif G, Arfvidsson, Cecilia, Egnell, Ann-Charlotte, Rudvik, Anna, Kjaer, Magnus, Collén, Anna, Thompson, James D, Joyal, John, Chialda, Ligia, Koernicke, Thomas, Fuhr, Rainard, Chien, Kenneth R, Fritsche-Danielson, Regina
Published in Nature communications (20.02.2019)
Published in Nature communications (20.02.2019)
Get full text
Journal Article
Unlocking the promise of mRNA therapeutics
Rohner, Eduarde, Yang, Ran, Foo, Kylie S, Goedel, Alexander, Chien, Kenneth R
Published in Nature biotechnology (01.11.2022)
Published in Nature biotechnology (01.11.2022)
Get full text
Journal Article
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
Zangi, Lior, Lui, Kathy O, von Gise, Alexander, Ma, Qing, Ebina, Wataru, Ptaszek, Leon M, Später, Daniela, Xu, Huansheng, Tabebordbar, Mohammadsharif, Gorbatov, Rostic, Sena, Brena, Nahrendorf, Matthias, Briscoe, David M, Li, Ronald A, Wagers, Amy J, Rossi, Derrick J, Pu, William T, Chien, Kenneth R
Published in Nature biotechnology (01.10.2013)
Published in Nature biotechnology (01.10.2013)
Get full text
Journal Article
Embryonic heart progenitors and cardiogenesis
Brade, Thomas, Pane, Luna S, Moretti, Alessandra, Chien, Kenneth R, Laugwitz, Karl-Ludwig
Published in Cold Spring Harbor perspectives in medicine (01.10.2013)
Published in Cold Spring Harbor perspectives in medicine (01.10.2013)
Get full text
Journal Article
Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract
Sahara, Makoto, Santoro, Federica, Sohlmér, Jesper, Zhou, Chikai, Witman, Nevin, Leung, Chuen Yan, Mononen, Mimmi, Bylund, Kristine, Gruber, Peter, Chien, Kenneth R.
Published in Developmental cell (25.02.2019)
Published in Developmental cell (25.02.2019)
Get full text
Journal Article
How to make a cardiomyocyte
Später, Daniela, Hansson, Emil M, Zangi, Lior, Chien, Kenneth R
Published in Development (Cambridge) (01.12.2014)
Published in Development (Cambridge) (01.12.2014)
Get full text
Journal Article
Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update
Sarin, S. K., Kumar, M., Lau, G. K., Abbas, Z., Chan, H. L. Y., Chen, C. J., Chen, D. S., Chen, H. L., Chen, P. J., Chien, R. N., Dokmeci, A. K., Gane, Ed, Hou, J. L., Jafri, W., Jia, J., Kim, J. H., Lai, C. L., Lee, H. C., Lim, S. G., Liu, C. J., Locarnini, S., Al Mahtab, M., Mohamed, R., Omata, M., Park, J., Piratvisuth, T., Sharma, B. C., Sollano, J., Wang, F. S., Wei, L., Yuen, M. F., Zheng, S. S., Kao, J. H.
Published in Hepatology international (01.01.2016)
Published in Hepatology international (01.01.2016)
Get full text
Journal Article
Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells
Drawnel, Faye M., Boccardo, Stefano, Prummer, Michael, Delobel, Frédéric, Graff, Alexandra, Weber, Michael, Gérard, Régine, Badi, Laura, Kam-Thong, Tony, Bu, Lei, Jiang, Xin, Hoflack, Jean-Christophe, Kiialainen, Anna, Jeworutzki, Elena, Aoyama, Natsuyo, Carlson, Coby, Burcin, Mark, Gromo, Gianni, Boehringer, Markus, Stahlberg, Henning, Hall, Benjamin J., Magnone, Maria Chiara, Kolaja, Kyle, Chien, Kenneth R., Bailly, Jacques, Iacone, Roberto
Published in Cell reports (Cambridge) (06.11.2014)
Published in Cell reports (Cambridge) (06.11.2014)
Get full text
Journal Article
Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells
Sahara, Makoto, Hansson, Emil M, Wernet, Oliver, Lui, Kathy O, Später, Daniela, Chien, Kenneth R
Published in Cell research (01.07.2014)
Published in Cell research (01.07.2014)
Get full text
Journal Article
Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI
Ai, Xuefeng, Yan, Bingqian, Witman, Nevin, Gong, Yiqi, Yang, Li, Tan, Yao, Chen, Ying, Liu, Minglu, Lu, Tingting, Luo, Runjiao, Wang, Huijing, Chien, Kenneth R., Wang, Wei, Fu, Wei
Published in Molecular therapy (04.01.2023)
Published in Molecular therapy (04.01.2023)
Get full text
Journal Article
Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing
Sun, Naidi, Ning, Bo, Hansson, Kenny M, Bruce, Anthony C, Seaman, Scott A, Zhang, Chenchu, Rikard, Michaela, DeRosa, Christopher A, Fraser, Cassandra L, Wågberg, Maria, Fritsche-Danielson, Regina, Wikström, Johannes, Chien, Kenneth R, Lundahl, Anna, Hölttä, Mikko, Carlsson, Leif G, Peirce, Shayn M, Hu, Song
Published in Scientific reports (30.11.2018)
Published in Scientific reports (30.11.2018)
Get full text
Journal Article
Bioengineering heart muscle: a paradigm for regenerative medicine
Vunjak-Novakovic, Gordana, Lui, Kathy O, Tandon, Nina, Chien, Kenneth R
Published in Annual review of biomedical engineering (15.08.2011)
Published in Annual review of biomedical engineering (15.08.2011)
Get more information
Journal Article
Author Correction: Placental growth factor exerts a dual function for cardiomyogenesis and vasculogenesis during heart development
Witman, Nevin, Zhou, Chikai, Häneke, Timm, Xiao, Yao, Huang, Xiaoting, Rohner, Eduarde, Sohlmér, Jesper, Grote Beverborg, Niels, Lehtinen, Miia L, Chien, Kenneth R, Sahara, Makoto
Published in Nature communications (04.01.2024)
Published in Nature communications (04.01.2024)
Get full text
Journal Article
Amnion signals are essential for mesoderm formation in primates
Yang, Ran, Goedel, Alexander, Kang, Yu, Si, Chenyang, Chu, Chu, Zheng, Yi, Chen, Zhenzhen, Gruber, Peter J, Xiao, Yao, Zhou, Chikai, Witman, Nevin, Eroglu, Elif, Leung, Chuen-Yan, Chen, Yongchang, Fu, Jianping, Ji, Weizhi, Lanner, Fredrik, Niu, Yuyu, Chien, Kenneth R
Published in Nature communications (26.08.2021)
Published in Nature communications (26.08.2021)
Get full text
Journal Article
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
Yoshimura, Akihiko, Mori, Hiroyuki, Hanada, Reiko, Hanada, Toshikatsu, Aki, Daisuke, Mashima, Ryuichi, Nishinakamura, Hitomi, Torisu, Takehiro, Chien, Kenneth R, Yasukawa, Hideo
Published in Nature medicine (01.07.2004)
Published in Nature medicine (01.07.2004)
Get full text
Journal Article