An Acetylation Switch Regulates SUMO-Dependent Protein Interaction Networks
Ullmann, Rebecca, Chien, Christopher D., Avantaggiati, Maria Laura, Muller, Stefan
Published in Molecular cell (29.06.2012)
Published in Molecular cell (29.06.2012)
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CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
Jacoby, Elad, Nguyen, Sang M., Fountaine, Thomas J., Welp, Kathryn, Gryder, Berkley, Qin, Haiying, Yang, Yinmeng, Chien, Christopher D., Seif, Alix E., Lei, Haiyan, Song, Young K., Khan, Javed, Lee, Daniel W., Mackall, Crystal L., Gardner, Rebecca A., Jensen, Michael C., Shern, Jack F., Fry, Terry J.
Published in Nature communications (27.07.2016)
Published in Nature communications (27.07.2016)
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Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3 - mutant acute myeloid leukemia and KMT2A -rearranged acute lymphoblastic leukemia
Niswander, Lisa M, Graff, Zachary T, Chien, Christopher D, Chukinas, John A, Meadows, Christina A, Leach, Lillie C, Loftus, Joseph P, Kohler, M Eric, Tasian, Sarah K, Fry, Terry J
Published in Haematologica (Roma) (01.02.2023)
Published in Haematologica (Roma) (01.02.2023)
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design
Qin, Haiying, Yang, Lila, Chukinas, John A, Shah, Nirali N, Tarun, Samiksha, Pouzolles, Marie, Chien, Christopher D, Niswander, Lisa M, Welch, Anthony R, Taylor, Naomi A, Tasian, Sarah K, Fry, Terry J
Published in Journal for immunotherapy of cancer (01.09.2021)
Published in Journal for immunotherapy of cancer (01.09.2021)
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Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and γδ T cell output
Song, Hannah W., Benzaoui, Mehdi, Dwivedi, Alka, Underwood, Sarah, Shao, Lipei, Achar, Sooraj, Posarac, Vesna, Remley, Victoria A., Prochazkova, Michaela, Cai, Yihua, Jin, Ping, Somerville, Robert P., Stroncek, David F., Altan-Bonnet, Grégoire, Shah, Nirali N., Chien, Christopher D., Taylor, Naomi, Highfill, Steven L.
Published in Molecular therapy. Methods & clinical development (14.03.2024)
Published in Molecular therapy. Methods & clinical development (14.03.2024)
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Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD
Capitini, Christian M., Nasholm, Nicole M., Chien, Christopher D., Larabee, Shannon M., Qin, Haiying, Song, Young K., Klover, Peter J., Hennighausen, Lothar, Khan, Javed, Fry, Terry J.
Published in Blood (18.09.2014)
Published in Blood (18.09.2014)
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Tyrosine Phosphorylation of the Nuclear Receptor Coactivator AIB1/SRC-3 Is Enhanced by Abl Kinase and Is Required for Its Activity in Cancer Cells
Oh, Annabell S., Lahusen, John T., Chien, Christopher D., Fereshteh, Mark P., Zhang, Xiaolong, Dakshanamurthy, Sivanesan, Xu, Jianming, Kagan, Benjamin L., Wellstein, Anton, Riegel, Anna T.
Published in Molecular and Cellular Biology (01.11.2008)
Published in Molecular and Cellular Biology (01.11.2008)
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TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
Yang, Yinmeng, Kohler, M Eric, Chien, Christopher D, Sauter, Christopher T, Jacoby, Elad, Yan, Chunhua, Hu, Ying, Wanhainen, Kelsey, Qin, Haiying, Fry, Terry J
Published in Science translational medicine (22.11.2017)
Published in Science translational medicine (22.11.2017)
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CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR
Shalabi, Haneen, Qin, Haiying, Su, Angela, Yates, Bonnie, Wolters, Pamela L., Steinberg, Seth M., Ligon, John A., Silbert, Sara, DéDé, Kniya, Benzaoui, Mehdi, Goldberg, Sophia, Achar, Sooraj, Schneider, Dina, Shahani, Shilpa A., Little, Lauren, Foley, Toni, Molina, John C., Panch, Sandhya, Mackall, Crystal L., Lee, Daniel W., Chien, Christopher D., Pouzolles, Marie, Ahlman, Mark, Yuan, Constance M., Wang, Hao-Wei, Wang, Yanyu, Inglefield, Jon, Toledo-Tamula, Mary Anne, Martin, Staci, Highfill, Steven L., Altan-Bonnet, Gregoire, Stroncek, David, Fry, Terry J., Taylor, Naomi, Shah, Nirali N.
Published in Blood (04.08.2022)
Published in Blood (04.08.2022)
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Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients
Ishii, Kazusa, Pouzolles, Marie, Chien, Christopher D, Erwin-Cohen, Rebecca A, Kohler, M Eric, Qin, Haiying, Lei, Haiyan, Kuhn, Skyler, Ombrello, Amanda K, Dulau-Florea, Alina, Eckhaus, Michael A, Shalabi, Haneen, Yates, Bonnie, Lichtenstein, Daniel A, Zimmermann, Valérie S, Kondo, Taisuke, Shern, Jack F, Young, Howard A, Taylor, Naomi, Shah, Nirali N, Fry, Terry J
Published in The Journal of clinical investigation (01.10.2020)
Published in The Journal of clinical investigation (01.10.2020)
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Role of the Nuclear Receptor Coactivator AIB1-Δ4 Splice Variant in the Control of Gene Transcription
Chien, Christopher D., Kirilyuk, Alexander, Li, Jordan V., Zhang, Wentao, Lahusen, Tyler, Schmidt, Marcel O., Oh, Annabell S., Wellstein, Anton, Riegel, Anna T.
Published in The Journal of biological chemistry (29.07.2011)
Published in The Journal of biological chemistry (29.07.2011)
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Vaccination regimens incorporating CpG-containing oligodeoxynucleotides and IL-2 generate antigen-specific antitumor immunity from T-cell populations undergoing homeostatic peripheral expansion after BMT
Kochenderfer, James N., Simpson, Jessica L., Chien, Christopher D., Gress, Ronald E.
Published in Blood (01.07.2007)
Published in Blood (01.07.2007)
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Synergism between CpG-Containing Oligodeoxynucleotides and IL-2 Causes Dramatic Enhancement of Vaccine-Elicited CD8+ T Cell Responses
Kochenderfer, James N, Chien, Christopher D, Simpson, Jessica L, Gress, Ronald E
Published in The Journal of immunology (1950) (15.12.2006)
Published in The Journal of immunology (1950) (15.12.2006)
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In vivo magnetic resonance volumetric and spectroscopic analysis of mouse prostate Cancer Models
Fricke, Stanley T., Rodriguez, Olga, VanMeter, John, Dettin, Luis E., Casimiro, Mathew, Chien, Christopher D., Newell, Tionanatasha, Johnson, Kevin, Ileva, Lilia, Ojeifo, John, Johnson, Michael D., Albanese, Chris
Published in The Prostate (15.05.2006)
Published in The Prostate (15.05.2006)
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