Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights
Baartzes, N., Stringer, T., Seldon, R., Warner, D.F., Taylor, D., Wittlin, S., Chibale, K., Smith, G.S.
Published in European journal of medicinal chemistry (15.10.2019)
Published in European journal of medicinal chemistry (15.10.2019)
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1086 POSTER Identification of the Receptor Tyrosine Kinase AXL as a New Target for Prostate Cancer Therapy
Paccez, J.D, Vasquez, G, Tamura, R.E, Duncan, K, Campesato, L.F, Vasconcellos, J, Chibale, K, Liberman, T, Zerbini, L.F
Published in European journal of cancer (1990) (2011)
Published in European journal of cancer (1990) (2011)
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Crystal structures of sampatrilat and sampatrilat‐Asp in complex with human ACE – a molecular basis for domain selectivity
Cozier, Gyles E., Schwager, Sylva L., Sharma, Rajni K., Chibale, Kelly, Sturrock, Edward D., Acharya, K. Ravi
Published in The FEBS journal (01.04.2018)
Published in The FEBS journal (01.04.2018)
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Novel web-based tools combining chemistry informatics, biology and social networks for drug discovery
Hohman, Moses, Gregory, Kellan, Chibale, Kelly, Smith, Peter J., Ekins, Sean, Bunin, Barry
Published in Drug discovery today (01.03.2009)
Published in Drug discovery today (01.03.2009)
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Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives
Chiyanzu, Idan, Clarkson, Cailean, Smith, Peter J., Lehman, Julie, Gut, Jiri, Rosenthal, Philip J., Chibale, Kelly
Published in Bioorganic & medicinal chemistry (02.05.2005)
Published in Bioorganic & medicinal chemistry (02.05.2005)
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Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi
Greenbaum, Doron C, Mackey, Zachary, Hansell, Elizabeth, Doyle, Patricia, Gut, Jiri, Caffrey, Conor R, Lehrman, Julia, Rosenthal, Philip J, McKerrow, James H, Chibale, Kelly
Published in Journal of medicinal chemistry (03.06.2004)
Published in Journal of medicinal chemistry (03.06.2004)
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Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain
CHIYANZU, Idan, HANSELL, Elizabeth, GUT, Jiri, ROSENTHAL, Philip J, MCKERROW, James H, CHIBALE, Kelly
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
Synthesis and antiplasmodial activity in vitro of new ferrocene–chloroquine analogues
Beagley, Paul, Blackie, Margaret A. L., Chibale, Kelly, Clarkson, Cailean, Meijboom, Reinout, Moss, John R., Smith, Peter J., Su, Hong
Published in Dalton transactions : an international journal of inorganic chemistry (2003)
Published in Dalton transactions : an international journal of inorganic chemistry (2003)
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Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore
Pillay, Pamisha, Vleggaar, Robert, Maharaj, Vinesh J., Smith, Peter J., Lategan, Carmen A., Chouteau, Frank, Chibale, Kelly
Published in Phytochemistry (Oxford) (01.04.2007)
Published in Phytochemistry (Oxford) (01.04.2007)
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Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts
Musonda, Chitalu C, Taylor, Dale, Lehman, Julie, Gut, Jiri, Rosenthal, Philip J, Chibale, Kelly
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
Published in Bioorganic & medicinal chemistry letters (02.08.2004)
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Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine
Chibale, Kelly, Haupt, Hayley, Kendrick, Howard, Yardley, Vanessa, Saravanamuthu, Ahilan, Fairlamb, Alan H, Croft, Simon L
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
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Exploiting a basic chemosensitizing pharmacophore hypothesis. Part 1: Synthesis and biological evaluation of novel arylbromide and bicyclic chemosensitizers against drug-resistant malaria parasites
Chouteau, Franck, Ramanitrahasimbola, David, Rasoanaivo, Philippe, Chibale, Kelly
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
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