Combining epigenetic and immune therapy to overcome cancer resistance
Gomez, Stephanie, Tabernacki, Tomasz, Kobyra, Julie, Roberts, Paige, Chiappinelli, Katherine B.
Published in Seminars in cancer biology (01.10.2020)
Published in Seminars in cancer biology (01.10.2020)
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Journal Article
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Buhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner
Published in Cell (27.08.2015)
Published in Cell (27.08.2015)
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Journal Article
Combining Epigenetic and Immunotherapy to Combat Cancer
Chiappinelli, Katherine B, Zahnow, Cynthia A, Ahuja, Nita, Baylin, Stephen B
Published in Cancer research (Chicago, Ill.) (01.04.2016)
Published in Cancer research (Chicago, Ill.) (01.04.2016)
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Journal Article
Inhibiting DNA methylation improves antitumor immunity in ovarian cancer
Chiappinelli, Katherine B, Baylin, Stephen B
Published in The Journal of clinical investigation (15.07.2022)
Published in The Journal of clinical investigation (15.07.2022)
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Journal Article
Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
Topper, Michael J., Vaz, Michelle, Chiappinelli, Katherine B., DeStefano Shields, Christina E., Niknafs, Noushin, Yen, Ray-Whay Chiu, Wenzel, Alyssa, Hicks, Jessica, Ballew, Matthew, Stone, Meredith, Tran, Phuoc T., Zahnow, Cynthia A., Hellmann, Matthew D., Anagnostou, Valsamo, Strissel, Pamela L., Strick, Reiner, Velculescu, Victor E., Baylin, Stephen B.
Published in Cell (30.11.2017)
Published in Cell (30.11.2017)
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Journal Article
Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells
Siebenkäs, Cornelia, Chiappinelli, Katherine B, Guzzetta, Angela A, Sharma, Anup, Jeschke, Jana, Vatapalli, Rajita, Baylin, Stephen B, Ahuja, Nita
Published in PloS one (16.06.2017)
Published in PloS one (16.06.2017)
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Journal Article
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2017)
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Journal Article
Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers
Li, Huili, Chiappinelli, Katherine B, Guzzetta, Angela A, Easwaran, Hariharan, Yen, Ray-Whay Chiu, Vatapalli, Rajita, Topper, Michael J, Luo, Jianjun, Connolly, Roisin M, Azad, Nilofer S, Stearns, Vered, Pardoll, Drew M, Davidson, Nancy, Jones, Peter A, Slamon, Dennis J, Baylin, Stephen B, Zahnow, Cynthia A, Ahuja, Nita
Published in Oncotarget (15.02.2014)
Published in Oncotarget (15.02.2014)
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Journal Article
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Budhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner
Published in Cell (06.04.2017)
Published in Cell (06.04.2017)
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Journal Article
Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer
JOO MI YI, GUZZETTA, Angela A, PAPPOU, Emmanouil P, LACOBUZIO-DONAHUE, Christine A, GOGGINS, Michael G, HERMAN, James G, WANG, Tza-Huei, BAYLIN, Stephen B, AHUJA, Nita, BAILEY, Vasudev J, DOWNING, Stephanie R, VAN NESTE, Leander, CHIAPPINELLI, Katherine B, KEELEY, Brian P, STARK, Alejandro, HERRERA, Alexander, WOLFGANG, Christopher
Published in Clinical cancer research (01.12.2013)
Published in Clinical cancer research (01.12.2013)
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Journal Article
Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors
Kim, Dae Joong, Anandh, Swetha, Null, Jamie L., Przanowski, Piotr, Bhatnagar, Sanchita, Kumar, Pankaj, Shelton, Sarah E., Grundy, Erin E., Chiappinelli, Katherine B., Kamm, Roger D., Barbie, David A., Dudley, Andrew C.
Published in Nature communications (14.04.2023)
Published in Nature communications (14.04.2023)
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Journal Article
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Budhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner
Published in Cell (25.02.2016)
Published in Cell (25.02.2016)
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Journal Article
Editorial: Genetic and Epigenetic Control of Immune Responses
Noonepalle, Satish Kumar R, Karabon, Lidia, Chiappinelli, Katherine B, Villagra, Alejandro
Published in Frontiers in immunology (05.10.2021)
Published in Frontiers in immunology (05.10.2021)
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Journal Article
Correction: Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells
Siebenkäs, Cornelia, Chiappinelli, Katherine B, Guzzetta, Angela A, Sharma, Anup, Jeschke, Jana, Vatapalli, Rajita, Baylin, Stephen B, Ahuja, Nita
Published in PloS one (10.12.2020)
Published in PloS one (10.12.2020)
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Journal Article
Cell therapy using ex vivo reprogrammed macrophages enhances antitumor immune responses in melanoma
Noonepalle, Satish Kumar Reddy, Gracia-Hernandez, Maria, Aghdam, Nima, Berrigan, Michael, Coulibaly, Hawa, Li, Xintang, Zevallos-Delgado, Christian, Pletcher, Andrew, Weselman, Bryan, Palmer, Erica, Knox, Tessa, Sotomayor, Eduardo, Chiappinelli, Katherine B, Wardrop, Duncan, Horvath, Anelia, Shook, Brett A, Lee, Norman, Dritschilo, Anatoly, Fernandes, Rohan, Musunuri, Karthik, Shibata, Maho, Villagra, Alejandro
Published in Journal of experimental & clinical cancer research (14.09.2024)
Published in Journal of experimental & clinical cancer research (14.09.2024)
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Journal Article
Author Correction: Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer
Moufarrij, Sara, Srivastava, Aneil, Gomez, Stephanie, Hadley, Melissa, Palmer, Erica, Austin, Paul Tran, Chisholm, Sarah, Diab, Noor, Roche, Kyle, Yu, Angela, Li, Jing, Zhu, Wenge, Lopez-Acevedo, Micael, Villagra, Alejandro, Chiappinelli, Katherine B.
Published in Scientific reports (20.12.2021)
Published in Scientific reports (20.12.2021)
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Journal Article
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers
Zhang, Bo, Xing, XiaoYun, Li, Jing, Lowdon, Rebecca F, Zhou, Yan, Lin, Nan, Zhang, Baoxue, Sundaram, Vasavi, Chiappinelli, Katherine B, Hagemann, Ian S, Mutch, David G, Goodfellow, Paul J, Wang, Ting
Published in BMC genomics (06.10.2014)
Published in BMC genomics (06.10.2014)
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A T cell receptor specific for an HLA-A03:01-restricted epitope in the endogenous retrovirus ERV-K-Env exhibits limited recognition of its cognate epitope
Grundy, Erin E, Shaw, Lauren C, Wang, Loretta, Lee, Abigail V, Argueta, James Castro, Powell, Jr, Daniel J, Ostrowski, Mario, Jones, R Brad, Cruz, C Russell Y, Gordish-Dressman, Heather, Chappell, Nicole P, Bollard, Catherine M, Chiappinelli, Katherine B
Published in Mobile DNA (09.10.2024)
Published in Mobile DNA (09.10.2024)
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Journal Article
Meeting report: transposable elements at the crossroads of evolution, health and disease 2023
Arkhipova, Irina R, Burns, Kathleen H, Chiappinelli, Katherine B, Chuong, Edward B, Goubert, Clement, Guarné, Alba, Larracuente, Amanda M, Lee, E Alice, Levin, Henry L
Published in Mobile DNA (27.11.2023)
Published in Mobile DNA (27.11.2023)
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