Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins
Chi, Binkai, O’Connell, Jeremy D., Yamazaki, Tomohiro, Gangopadhyay, Jaya, Gygi, Steven P., Reed, Robin
Published in Scientific reports (08.06.2018)
Published in Scientific reports (08.06.2018)
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Journal Article
mRNAs are sorted for export or degradation before passing through nuclear speckles
Fan, Jing, Kuai, Bin, Wang, Ke, Wang, Lantian, Wang, Yimin, Wu, Xudong, Chi, Binkai, Li, Guohui, Cheng, Hong
Published in Nucleic acids research (19.09.2018)
Published in Nucleic acids research (19.09.2018)
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Journal Article
The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex
Chi, Binkai, O'Connell, Jeremy D, Iocolano, Alexander D, Coady, Jordan A, Yu, Yong, Gangopadhyay, Jaya, Gygi, Steven P, Reed, Robin
Published in Nucleic acids research (14.12.2018)
Published in Nucleic acids research (14.12.2018)
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Journal Article
U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish
Yu, Yong, Chi, Binkai, Xia, Wei, Gangopadhyay, Jaya, Yamazaki, Tomohiro, Winkelbauer-Hurt, Marlene E, Yin, Shanye, Eliasse, Yoan, Adams, Edward, Shaw, Christopher E, Reed, Robin
Published in Nucleic acids research (31.03.2015)
Published in Nucleic acids research (31.03.2015)
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Journal Article
NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction
Wang, Jianshu, Chen, Jiyun, Wu, Guifen, Zhang, Hongling, Du, Xian, Chen, Suli, Zhang, Li, Wang, Ke, Fan, Jing, Gao, Shuaixin, Wu, Xudong, Zhang, Shouxiang, Kuai, Bin, Zhao, Peng, Chi, Binkai, Wang, Lantian, Li, Guohui, Wong, Catherine C L, Zhou, Yu, Li, Jinsong, Yun, Caihong, Cheng, Hong
Published in Genes & development (01.05.2019)
Published in Genes & development (01.05.2019)
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Journal Article
A U2-snRNP–independent role of SF3b in promoting mRNA export
Wang, Ke, Yin, Changping, Du, Xian, Chen, Suli, Wang, Jianshu, Zhang, Li, Wang, Lantian, Yu, Yong, Chi, Binkai, Shi, Min, Wang, Changshou, Reed, Robin, Zhou, Yu, Huang, Jing, Cheng, Hong
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
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Journal Article
Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA
Chi, Binkai, Wang, Qingliang, Wu, Guifen, Tan, Ming, Wang, Lantian, Shi, Min, Chang, Xingya, Cheng, Hong
Published in Nucleic acids research (01.01.2013)
Published in Nucleic acids research (01.01.2013)
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Journal Article
Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export
Fan, Jing, Kuai, Bin, Wu, Guifen, Wu, Xudong, Chi, Binkai, Wang, Lantian, Wang, Ke, Shi, Zhubing, Zhang, Heng, Chen, She, He, Zhisong, Wang, Siyuan, Zhou, Zhaocai, Li, Guohui, Cheng, Hong
Published in The EMBO journal (02.10.2017)
Published in The EMBO journal (02.10.2017)
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Journal Article
Causal ALS genes impact the MHC class II antigen presentation pathway
Chi, Binkai, Öztürk, Muhammet M, Paraggio, Christina L, Leonard, Claudia E, Sanita, Maria E, Dastpak, Mahtab, O'Connell, Jeremy D, Coady, Jordan A, Zhang, Jiuchun, Gygi, Steven P, Lopez-Gonzalez, Rodrigo, Yin, Shanye, Reed, Robin
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2023)
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Journal Article
A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18
Chi, Binkai, Wang, Ke, Du, Yanhua, Gui, Bin, Chang, Xingya, Wang, Lantian, Fan, Jing, Chen, She, Wu, Xudong, Li, Guohui, Cheng, Hong
Published in Nucleic acids research (17.06.2014)
Published in Nucleic acids research (17.06.2014)
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Journal Article
Exosome cofactor hMTR 4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export
Fan, Jing, Kuai, Bin, Wu, Guifen, Wu, Xudong, Chi, Binkai, Wang, Lantian, Wang, Ke, Shi, Zhubing, Zhang, Heng, Chen, She, He, Zhisong, Wang, Siyuan, Zhou, Zhaocai, Li, Guohui, Cheng, Hong
Published in The EMBO journal (02.10.2017)
Published in The EMBO journal (02.10.2017)
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Journal Article
Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers
Dastpak, Mahtab, Kim, Hyunmin, Paraggio, Christina L, Leonard, Claudia E, Yin, Shanye, Binkai Chi, Nassar, Kelsey W, R Grant Rowe, Hou, Zhonggang, Zhang, Jiuchun, Cohn, Erin F, Yang, Na, Marion, William, Zhang, Yosra, Daley, George Q, Reed, Robin
Published in bioRxiv (31.03.2022)
Published in bioRxiv (31.03.2022)
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