Germline BAP1 mutations predispose to malignant mesothelioma
Testa, Joseph R, Carbone, Michele, Cheung, Mitchell, Pei, Jianming, Below, Jennifer E, Tan, Yinfei, Sementino, Eleonora, Cox, Nancy J, Dogan, A Umran, Pass, Harvey I, Trusa, Sandra, Hesdorffer, Mary, Nasu, Masaki, Powers, Amy, Rivera, Zeyana, Comertpay, Sabahattin, Tanji, Mika, Gaudino, Giovanni, Yang, Haining
Published in Nature genetics (01.10.2011)
Published in Nature genetics (01.10.2011)
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Journal Article
Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations
Kadariya, Yuwaraj, Cheung, Mitchell, Xu, Jinfei, Pei, Jianming, Sementino, Eleonora, Menges, Craig W, Cai, Kathy Q, Rauscher, Frank J, Klein-Szanto, Andres J, Testa, Joseph R
Published in Cancer research (Chicago, Ill.) (01.05.2016)
Published in Cancer research (Chicago, Ill.) (01.05.2016)
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Journal Article
Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma
JINFEI XU, KADARIYA, Yuwaraj, HONGZHUANG PENG, KARAR, Jayashree, RAUSCHER, Frank J, TESTA, Joseph R, CHEUNG, Mitchell, JIANMING PEI, TALARCHEK, Jacqueline, SEMENTINO, Eleonora, YINFEI TAN, MENGES, Craig W, CAI, Kathy Q, LITWIN, Samuel
Published in Cancer research (Chicago, Ill.) (15.08.2014)
Published in Cancer research (Chicago, Ill.) (15.08.2014)
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Journal Article
RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model
Mabuchi, Seiji, Altomare, Deborah A, Cheung, Mitchell, Zhang, Lili, Poulikakos, Poulikos I, Hensley, Harvey H, Schilder, Russell J, Ozols, Robert F, Testa, Joseph R
Published in Clinical cancer research (15.07.2007)
Published in Clinical cancer research (15.07.2007)
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Journal Article
Deregulated Akt3 activity promotes development of malignant melanoma
STAHL, Jill M, SHARMA, Arati, CHEUNG, Mitchell, ZIMMERMAN, Melissa, CHENG, Jin Q, BOSENBERG, Marcus W, KESTER, Mark, SANDIRASEGARANE, Lakshman, ROBERTSON, Gavin P
Published in Cancer research (Chicago, Ill.) (01.10.2004)
Published in Cancer research (Chicago, Ill.) (01.10.2004)
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Journal Article
Regulation of B-Raf Kinase Activity by Tuberin and Rheb Is Mammalian Target of Rapamycin (mTOR)-independent
Karbowniczek, Magdalena, Cash, Timothy, Cheung, Mitchell, Robertson, Gavin P, Astrinidis, Aristotelis, Henske, Elizabeth Petri
Published in The Journal of biological chemistry (16.07.2004)
Published in The Journal of biological chemistry (16.07.2004)
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Journal Article
Akt3 and Mutant V600EB-Raf Cooperate to Promote Early Melanoma Development
Cheung, Mitchell, Sharma, Arati, Madhunapantula, SubbaRao V., Robertson, Gavin P.
Published in Cancer research (Chicago, Ill.) (01.05.2008)
Published in Cancer research (Chicago, Ill.) (01.05.2008)
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Journal Article
Alterations of the AKT Pathway in Sporadic Human Tumors, Inherited Susceptibility to Cancer, and Overgrowth Syndromes
Menges, Craig W, Hassan, Dalal, Cheung, Mitchell, Bellacosa, Alfonso, Testa, Joseph R
Published in Current topics in microbiology and immunology (28.08.2024)
Published in Current topics in microbiology and immunology (28.08.2024)
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Journal Article
Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer
Ohar, Jill A, Cheung, Mitchell, Talarchek, Jacqueline, Howard, Suzanne E, Howard, Timothy D, Hesdorffer, Mary, Peng, Hongzhuang, Rauscher, Frank J, Testa, Joseph R
Published in Cancer research (Chicago, Ill.) (15.01.2016)
Published in Cancer research (Chicago, Ill.) (15.01.2016)
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Journal Article
Novel LRRK2 mutations and other rare, non-BAP1-related candidate tumor predisposition gene variants in high-risk cancer families with mesothelioma and other tumors
Cheung, Mitchell, Kadariya, Yuwaraj, Sementino, Eleonora, Hall, Michael J, Cozzi, Ilaria, Ascoli, Valeria, Ohar, Jill A, Testa, Joseph R
Published in Human molecular genetics (28.08.2021)
Published in Human molecular genetics (28.08.2021)
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Journal Article
Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
Tan, Yinfei, Sementino, Eleonora, Cheung, Mitchell, Peri, Suraj, Menges, Craig W, Kukuyan, Anna-Mariya, Zhang, Ting, Khazak, Vladimir, Fox, Lauren A, Ross, Eric A, Ramanathan, Suresh, Jhanwar, Suresh C, Flores, Raja M, Balachandran, Siddharth, Testa, Joseph R
Published in Clinical cancer research (15.02.2021)
Published in Clinical cancer research (15.02.2021)
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Journal Article
Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models
Kukuyan, Anna-Mariya, Sementino, Eleonora, Kadariya, Yuwaraj, Menges, Craig W, Cheung, Mitchell, Tan, Yinfei, Cai, Kathy Q, Slifker, Michael J, Peri, Suraj, Klein-Szanto, Andres J, Rauscher, 3rd, Frank J, Testa, Joseph R
Published in Cancer research (Chicago, Ill.) (15.08.2019)
Published in Cancer research (Chicago, Ill.) (15.08.2019)
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Journal Article
Germline BAP1 mutation in a family with high incidence of multiple primary cancers and a potential gene–environment interaction
Cheung, Mitchell, Kadariya, Yuwaraj, Talarchek, Jacqueline, Pei, Jianming, Ohar, Jill A, Kayaleh, Omar R, Testa, Joseph R
Published in Cancer letters (28.12.2015)
Published in Cancer letters (28.12.2015)
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Journal Article
Abstract 1232: Familial mesothelioma: Beyond BAP1
Cheung, Mitchell, Ohar, Jill A., Howard, Suzanne E., Howard, Timothy D., Hesdorffer, Mary, Testa, Joseph R.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling
Sementino, Eleonora, Kadariya, Yuwaraj, Cheung, Mitchell, Menges, Craig W, Tan, Yinfei, Kukuyan, Anna-Mariya, Shrestha, Ujjawal, Karchugina, Sofiia, Cai, Kathy Q, Peri, Suraj, Duncan, James S, Chernoff, Jonathan, Testa, Joseph R
Published in Molecular cancer research (04.05.2022)
Published in Molecular cancer research (04.05.2022)
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Journal Article
Abstract 2170: Effects of folic acid supplementation on early stages of colitis-associated carcinogenesis
Bartolomeu, Ariane Rocha, Chang, Wen-Chi, Vanderveer, Lisa, Harvey, Kristen N., Cheung, Mitchell, Cooper, Harry S., Clapper, Margie Lee
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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