Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER)
Cho, Eun-Ae, MBBS, Moloney, Fergal J, MD, Cai, Hong, MD, Au-Yeung, Annie, BSc, China, Carlos, MD, Scolyer, Richard A, Prof, Yosufi, Benafsha, BSc, Raftery, Mark J, PhD, Deng, Jason Z, PhD, Morton, Stephen W, PhD, Hammond, Paula T, Prof, Arkenau, Hendrik-Tobias, MD, Damian, Diona L, Prof, Francis, Douglas J, PhD, Chesterman, Colin N, Prof, Barnetson, Ross St C, Prof, Halliday, Gary M, Prof, Khachigian, Levon M, Prof
Published in The Lancet (British edition) (25.05.2013)
Published in The Lancet (British edition) (25.05.2013)
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Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun
Khachigian, Levon M, Fahmy, Roger G, Waldman, Alla, Zhang, Guishui, Mitchell, Ainslie, Tedla, Nicodemus, Cai, Hong, Geczy, Carolyn R, Chesterman, Colin N, Perry, Michael
Published in Nature biotechnology (01.07.2006)
Published in Nature biotechnology (01.07.2006)
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Role of Thrombospondin-1 in Control of von Willebrand Factor Multimer Size in Mice
Pimanda, John E, Ganderton, Tim, Maekawa, Akiko, Yap, Cindy L, Lawler, Jack, Kershaw, Geoff, Chesterman, Colin N, Hogg, Philip J
Published in The Journal of biological chemistry (14.05.2004)
Published in The Journal of biological chemistry (14.05.2004)
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Early Growth Response Factor-1 Induction by Injury Is Triggered by Release and Paracrine Activation by Fibroblast Growth Factor-2
Santiago, Fernando S., Lowe, Harry C., Day, Fiona L., Chesterman, Colin N., Khachigian, Levon M.
Published in The American journal of pathology (01.03.1999)
Published in The American journal of pathology (01.03.1999)
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The von Willebrand factor–reducing activity of thrombospondin-1 is located in the calcium-binding/C-terminal sequence and requires a free thiol at position 974
Pimanda, John E., Annis, Douglas S., Raftery, Mark, Mosher, Deane F., Chesterman, Colin N., Hogg, Philip J.
Published in Blood (15.10.2002)
Published in Blood (15.10.2002)
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Brothers in Arms: DNA Enzymes, Short Interfering RNA, and the Emerging Wave of Small-Molecule Nucleic Acid-Based Gene-Silencing Strategies
Bhindi, Ravinay, Fahmy, Roger G, Lowe, Harry C, Chesterman, Colin N, Dass, Crispin R, Cairns, Murray J, Saravolac, Edward G, Sun, Lun-Quan, Khachigian, Levon M
Published in The American journal of pathology (01.10.2007)
Published in The American journal of pathology (01.10.2007)
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DNAzyme targeting c-jun suppresses skin cancer growth
Cai, Hong, Santiago, Fernando S, Prado-Lourenco, Leonel, Wang, Bo, Patrikakis, Margaret, Davenport, Miles P, Maghzal, Ghassan J, Stocker, Roland, Parish, Christopher R, Chong, Beng H, Lieschke, Graham J, Wong, Tak-Wah, Chesterman, Colin N, Francis, Douglas J, Moloney, Fergal J, Barnetson, Ross St C, Halliday, Gary M, Khachigian, Levon M
Published in Science translational medicine (20.06.2012)
Published in Science translational medicine (20.06.2012)
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c-Jun DNAzymes Inhibit Myocardial Inflammation, ROS Generation, Infarct Size, and Improve Cardiac Function After Ischemia-Reperfusion Injury
XIAO LUO, HONG CAI, JUN NI, BHINDI, Ravinay, LOWE, Harry C, CHESTERMAN, Colin N, KHACHIGIAN, Levon M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2009)
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Anti‐PF4–heparin immunoglobulin G is the major class of heparin‐induced thrombocytopenia antibody: findings of an enzyme‐linked immunofiltration assay using membrane‐bound hPF4–heparin
Vun, Chee M., Evans, Sue, Chesterman, Colin N.
Published in British journal of haematology (01.01.2001)
Published in British journal of haematology (01.01.2001)
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Catalytic Oligodeoxynucleotides Define a Key Regulatory Role for Early Growth Response Factor-1 in the Porcine Model of Coronary In-Stent Restenosis
Lowe, Harry C, Fahmy, Roger G, Kavurma, Mary M, Baker, Andrew, Chesterman, Colin N, Khachigian, Levon M
Published in Circulation research (12.10.2001)
Published in Circulation research (12.10.2001)
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New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury
Santiago, Fernando S., Lowe, Harry C., Kavurma, Mary M., Chesterman, Colin N., Baker, Andrew, Atkins, David G., Khachigian, Levon M.
Published in Nature medicine (01.11.1999)
Published in Nature medicine (01.11.1999)
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Modulation of platelet and leucocyte function by a Chinese herbal formulation as compared with conventional antiplatelet agents
Zhao, Lian, Gaudry, Leonie, Dunkley, Scott, Brighton, Tim, Guo, Zhi Xin, Ye, Zheng Liang, Luo, Run Zhi, Chesterman, Colin N.
Published in Platelets (Edinburgh) (01.01.2008)
Published in Platelets (Edinburgh) (01.01.2008)
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Blockade of Vascular Smooth Muscle Cell Proliferation and Intimal Thickening After Balloon Injury by the Sulfated Oligosaccharide PI-88: Phosphomannopentaose Sulfate Directly Binds FGF-2, Blocks Cellular Signaling, and Inhibits Proliferation
Francis, Douglas J, Parish, Christopher R, McGarry, Mark, Santiago, Fernando S, Lowe, Harry C, Brown, Kathryn J, Bingley, John A, Hayward, Ian P, Cowden, William B, Campbell, Julie H, Campbell, Gordon R, Chesterman, Colin N, Khachigian, Levon M
Published in Circulation research (02.05.2003)
Published in Circulation research (02.05.2003)
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