Site-Specific Polysialylation of an Antitumor Single-Chain Fv Fragment
Constantinou, A, Epenetos, A. A, Hreczuk-Hirst, D, Jain, S, Wright, M, Chester, K. A, Deonarain, M. P
Published in Bioconjugate chemistry (20.05.2009)
Published in Bioconjugate chemistry (20.05.2009)
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Journal Article
Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT)
MAYER, A, SHARMA, S. K, TOLNER, B, MINTON, N. P, PURDY, D, AMLOT, P, THARAKAN, G, BEGENT, R. H. J, CHESTER, K. A
Published in British journal of cancer (14.06.2004)
Published in British journal of cancer (14.06.2004)
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Journal Article
Engineered single chain antibody fragments for radioimmunotherapy
Huhalov, A, Chester, K A
Published in The quarterly journal of nuclear medicine and molecular imaging (01.12.2004)
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Published in The quarterly journal of nuclear medicine and molecular imaging (01.12.2004)
Journal Article
A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor:receptor complex
COOKE, S. P, BOXER, G. M, LAWRENCE, L, PEDLEY, R. B, SPENCER, D. I. R, BEGENT, R. H. J, CHESTER, K. A
Published in Cancer research (Baltimore) (01.05.2001)
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Published in Cancer research (Baltimore) (01.05.2001)
Conference Proceeding
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From laboratory to Phase I/II cancer trials with recombinant biotherapeutics
Tolner, B, Smith, L, Hillyer, T, Bhatia, J, Beckett, P, Robson, L, Sharma, S.K, Griffin, N, Vervecken, W, Contreras, R, Pedley, R.B, Begent, R.H.J, Chester, K.A
Published in European journal of cancer (1990) (01.11.2007)
Published in European journal of cancer (1990) (01.11.2007)
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Journal Article
Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
Begent, R H, Verhaar, M J, Chester, K A, Casey, J L, Green, A J, Napier, M P, Hope-Stone, L D, Cushen, N, Keep, P A, Johnson, C J, Hawkins, R E, Hilson, A J, Robson, L
Published in Nature medicine (01.09.1996)
Published in Nature medicine (01.09.1996)
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Journal Article
Phage libraries for generation of clinically useful antibodies
Chester, K.A., Begent, R.H.J., Robson, L., Keep, P.A., Pedley, R.B., Boden LIBiol, J.A., Boxer, G., Green, A., Winter, G., Cochet, O., Hawkins, R.E.
Published in The Lancet (British edition) (19.02.1994)
Published in The Lancet (British edition) (19.02.1994)
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Journal Article
Catalytic activity of an in vivo tumor targeted anti-cea scFv: :carboxypeptidase G2 fusion protein
BHATIA, J, SHARMA, S. K, CHESTER, K. A, PEDLEY, R. B, BODEN, R. W, READ, D. A, BOXER, G. M, MICHAEL, N. P, BEGENT, R. H. J
Published in International journal of cancer (15.02.2000)
Published in International journal of cancer (15.02.2000)
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Journal Article
Enhanced tumour specificity of an anti-carcinoembrionic antigen Fab' fragment by poly(ethylene glycol) (PEG) modification
DELGADO, C, PEDLEY, R. B, HERRAEZ, A, BODEN, R, BODEN, J. A, KEEP, P. A, CHESTER, K. A, FISHER, D, BEGENT, R. H. J, FRANCIS, G. E
Published in British journal of cancer (01.01.1996)
Published in British journal of cancer (01.01.1996)
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Journal Article
Clinical issues in antibody design
Chester, Kerry A., Hawkins, Robert E.
Published in Trends in biotechnology (Regular ed.) (01.08.1995)
Published in Trends in biotechnology (Regular ed.) (01.08.1995)
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Journal Article
Taking engineered anti-CEA antibodies to the clinic
Mayer, A, Chester, K.A, Flynn, A.A, Begent, R.H.J
Published in Journal of immunological methods (10.12.1999)
Published in Journal of immunological methods (10.12.1999)
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Journal Article
Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer
CHESTER, K. A, MAYER, A, BEGENT, R. H. J, BHATIA, J, ROBSON, L, SPENCER, D. I. R, COOKE, S. P, FLYNN, A. A, SHARMA, S. K, BOXER, G, PEDLEY, R. B
Published in Cancer chemotherapy and pharmacology (2000)
Published in Cancer chemotherapy and pharmacology (2000)
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Conference Proceeding
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Preclinical Characterization and In Vivo Imaging Studies of an Engineered Recombinant Technetium-99m-Labeled Metallothionein-Containing Anti-Carcinoembryonic Antigen Single-Chain Antibody
Pietersz, Geoffrey A, Patrick, Mark R, Chester, Kerry A
Published in The Journal of nuclear medicine (1978) (01.01.1998)
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Published in The Journal of nuclear medicine (1978) (01.01.1998)
Journal Article
Exemplifying guidelines for preparation of recombinant DNA products in phase I trials in cancer: preparation of a genetically engineered anti-CEA single chain Fv antibody
Mayer, A, Chester, K.A, Bhatia, J, Pedley, R.B, Read, D.A, Boxer, G.M, Begent, R.H.J
Published in European journal of cancer (1990) (01.06.1998)
Published in European journal of cancer (1990) (01.06.1998)
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Journal Article
Technetium-99m Radiolabeling Using a Phage-Derived Single-Chain Fv with a C-Terminal Cysteine
Verhaar, Marlies J, Keep, Patricia A, Hawkins, Robert E, Robson, Lynda, Casey, Joanne L, Pedley, Barbara, Boden, Joan A, Begent, Richard H.J, Chester, Kerry A
Published in The Journal of nuclear medicine (1978) (01.05.1996)
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Published in The Journal of nuclear medicine (1978) (01.05.1996)
Journal Article
Clinical applications of phage-derived sFvs and sFv fusion proteins
Chester, K A, Bhatia, J, Boxer, G, Cooke, S P, Flynn, A A, Huhalov, A, Mayer, A, Pedley, R B, Robson, L, Sharma, S K, Spencer, D I, Begent, R H
Published in Disease markers (2000)
Published in Disease markers (2000)
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Journal Article
Increased expression of c-myc proto-oncogene in biopsies of ulcerative colitis and Crohn's colitis
Macpherson, A J, Chester, K A, Robson, L, Bjarnason, I, Malcolm, A D, Peters, T J
Published in Gut (01.05.1992)
Published in Gut (01.05.1992)
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