Sexual-dimorphism in human immune system aging
Márquez, Eladio J., Chung, Cheng-han, Marches, Radu, Rossi, Robert J., Nehar-Belaid, Djamel, Eroglu, Alper, Mellert, David J., Kuchel, George A., Banchereau, Jacques, Ucar, Duygu
Published in Nature communications (06.02.2020)
Published in Nature communications (06.02.2020)
Get full text
Journal Article
A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate
Caielli, Simone, Veiga, Diogo Troggian, Balasubramanian, Preetha, Athale, Shruti, Domic, Bojana, Murat, Elise, Banchereau, Romain, Xu, Zhaohui, Chandra, Manjari, Chung, Cheng-Han, Walters, Lynnette, Baisch, Jeanine, Wright, Tracey, Punaro, Marilynn, Nassi, Lorien, Stewart, Katie, Fuller, Julie, Ucar, Duygu, Ueno, Hideki, Zhou, Joseph, Banchereau, Jacques, Pascual, Virginia
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
Get full text
Journal Article
Mapping systemic lupus erythematosus heterogeneity at the single-cell level
Nehar-Belaid, Djamel, Hong, Seunghee, Marches, Radu, Chen, Guo, Bolisetty, Mohan, Baisch, Jeanine, Walters, Lynnette, Punaro, Marilynn, Rossi, Robert J., Chung, Cheng-Han, Huynh, Richie P., Singh, Prashant, Flynn, William F., Tabanor-Gayle, Joy-Ann, Kuchipudi, Navya, Mejias, Asuncion, Collet, Magalie A., Lucido, Anna Lisa, Palucka, Karolina, Robson, Paul, Lakshminarayanan, Santhanam, Ramilo, Octavio, Wright, Tracey, Pascual, Virginia, Banchereau, Jacques F.
Published in Nature immunology (01.09.2020)
Published in Nature immunology (01.09.2020)
Get full text
Journal Article
Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging
Karakaslar, Emin Onur, Katiyar, Neerja, Hasham, Muneer, Youn, Ahrim, Sharma, Siddhartha, Chung, Cheng‐han, Marches, Radu, Korstanje, Ron, Banchereau, Jacques, Ucar, Duygu
Published in Aging cell (01.04.2023)
Published in Aging cell (01.04.2023)
Get full text
Journal Article
The chromatin accessibility signature of human immune aging stems from CD8 + T cells
Ucar, Duygu, Márquez, Eladio J, Chung, Cheng-Han, Marches, Radu, Rossi, Robert J, Uyar, Asli, Wu, Te-Chia, George, Joshy, Stitzel, Michael L, Palucka, A Karolina, Kuchel, George A, Banchereau, Jacques
Published in The Journal of experimental medicine (02.10.2017)
Published in The Journal of experimental medicine (02.10.2017)
Get full text
Journal Article
Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency
Chung, Cheng-Han, Allen, Alexander G., Sullivan, Neil T., Atkins, Andrew, Nonnemacher, Michael R., Wigdahl, Brian, Dampier, Will
Published in Molecular therapy (08.01.2020)
Published in Molecular therapy (08.01.2020)
Get full text
Journal Article
Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants
Dampier, Will, Sullivan, Neil T., Chung, Cheng-Han, Mell, Joshua Chang, Nonnemacher, Michael R., Wigdahl, Brian
Published in Scientific reports (31.10.2017)
Published in Scientific reports (31.10.2017)
Get full text
Journal Article
Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection
Allen, Alexander G, Chung, Cheng-Han, Atkins, Andrew, Dampier, Will, Khalili, Kamel, Nonnemacher, Michael R, Wigdahl, Brian
Published in Frontiers in microbiology (17.12.2018)
Published in Frontiers in microbiology (17.12.2018)
Get full text
Journal Article
Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics
Dampier, Will, Sullivan, Neil T, Mell, Joshua Chang, Pirrone, Vanessa, Ehrlich, Garth D, Chung, Cheng-Han, Allen, Alexander G, DeSimone, Mathew, Zhong, Wen, Kercher, Katherine, Passic, Shendra, Williams, Jean W, Szep, Zsofia, Khalili, Kamel, Jacobson, Jeffrey M, Nonnemacher, Michael R, Wigdahl, Brian
Published in AIDS research and human retroviruses (01.11.2018)
Published in AIDS research and human retroviruses (01.11.2018)
Get more information
Journal Article
Dynamic association rules for gene expression data analysis
Chen, Shu-Chuan, Tsai, Tsung-Hsien, Chung, Cheng-Han, Li, Wen-Hsiung
Published in BMC genomics (14.10.2015)
Published in BMC genomics (14.10.2015)
Get full text
Journal Article
Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients
Sullivan, Neil T., Dampier, Will, Chung, Cheng-Han, Allen, Alexander G., Atkins, Andrew, Pirrone, Vanessa, Homan, Greg, Passic, Shendra, Williams, Jean, Zhong, Wen, Kercher, Katherine, Desimone, Mathew, Li, Luna, C. Antell, Gregory, Mell, Joshua Chang, Ehrlich, Garth D., Szep, Zsofia, Jacobson, Jeffrey M., Nonnemacher, Michael R., Wigdahl, Brian
Published in Scientific reports (19.11.2019)
Published in Scientific reports (19.11.2019)
Get full text
Journal Article
Off-Target Analysis in Gene Editing and Applications for Clinical Translation of CRISPR/Cas9 in HIV-1 Therapy
Atkins, Andrew, Chung, Cheng-Han, Allen, Alexander G, Dampier, Will, Gurrola, Theodore E, Sariyer, Ilker K, Nonnemacher, Michael R, Wigdahl, Brian
Published in Frontiers in genome editing (17.08.2021)
Published in Frontiers in genome editing (17.08.2021)
Get full text
Journal Article
Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing
Sullivan, Neil T, Allen, Alexander G, Atkins, Andrew J, Chung, Cheng-Han, Dampier, Will, Nonnemacher, Michael R, Wigdahl, Brian
Published in Frontiers in microbiology (12.08.2020)
Published in Frontiers in microbiology (12.08.2020)
Get full text
Journal Article
Production of rAAV by plasmid transfection induces antiviral and inflammatory responses in suspension HEK293 cells
Chung, Cheng-Han, Murphy, Christopher M., Wingate, Vincent P., Pavlicek, Jeffrey W., Nakashima, Reiko, Wei, Wei, McCarty, Douglas, Rabinowitz, Joseph, Barton, Erik
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Published in Molecular therapy. Methods & clinical development (09.03.2023)
Get full text
Journal Article
Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites
Chung, Cheng-Han, Allen, Alexander G., Atkins, Andrew J., Sullivan, Neil T., Homan, Greg, Costello, Robert, Madrid, Rebekah, Nonnemacher, Michael R., Dampier, Will, Wigdahl, Brian
Published in Molecular therapy. Nucleic acids (04.09.2020)
Published in Molecular therapy. Nucleic acids (04.09.2020)
Get full text
Journal Article
Computational Design of gRNAs Targeting Genetic Variants Across HIV-1 Subtypes for CRISPR-Mediated Antiviral Therapy
Chung, Cheng-Han, Allen, Alexander G, Atkins, Andrew, Link, Robert W, Nonnemacher, Michael R, Dampier, Will, Wigdahl, Brian
Published in Frontiers in cellular and infection microbiology (09.03.2021)
Published in Frontiers in cellular and infection microbiology (09.03.2021)
Get full text
Journal Article