Exploring the Role of Anionic Lipid Nanodomains in the Membrane Disruption and Protein Folding of Human Islet Amyloid Polypeptide Oligomers on Lipid Membrane Surfaces Using Multiscale Molecular Dynamics Simulations
Nguyen, Ngoc, Lewis, Amber, Pham, Thuong, Sikazwe, Donald, Cheng, Kwan H
Published in Molecules (Basel, Switzerland) (19.05.2023)
Published in Molecules (Basel, Switzerland) (19.05.2023)
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Journal Article
Multiscale Modeling of Macromolecular Interactions between Tau-Amylin Oligomers and Asymmetric Lipid Nanodomains That Link Alzheimer's and Diabetic Diseases
Santos, Natalia, Segura, Luthary, Lewis, Amber, Pham, Thuong, Cheng, Kwan H
Published in Molecules (Basel, Switzerland) (01.02.2024)
Published in Molecules (Basel, Switzerland) (01.02.2024)
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Journal Article
Design and Synthesis of New Acyl Urea Analogs as Potential σ1R Ligands
Thapa, Rajesh, Flores, Rafael, Cheng, Kwan H, Mochona, Bereket, Sikazwe, Donald
Published in Molecules (Basel, Switzerland) (02.03.2023)
Published in Molecules (Basel, Switzerland) (02.03.2023)
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Journal Article
Exploring Tau Fibril-Disaggregating and Antioxidating Molecules Binding to Membrane-Bound Amyloid Oligomers Using Machine Learning-Enhanced Docking and Molecular Dynamics
Segura, Luthary, Santos, Natalia, Flores, Rafael, Sikazwe, Donald, McGibbon, Miles, Blay, Vincent, Cheng, Kwan H
Published in Molecules (Basel, Switzerland) (01.06.2024)
Published in Molecules (Basel, Switzerland) (01.06.2024)
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Journal Article
Molecular Mechanisms of Protein–Lipid Interactions and Protein Folding of Heterogeneous Amylin and Tau Oligomers on Lipid Nanodomains That Link to Alzheimer’s
Santos, Natalia, Segura, Luthary, Lewis, Amber, Pham, Thuong, Cheng, Kwan H.
Published in Macromol (01.12.2023)
Published in Macromol (01.12.2023)
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Journal Article
Effects of Cholesterol in Stress-Related Neuronal Death-A Statistical Analysis Perspective
Dayeh, Maher A, Livadiotis, George, Aminian, Farzan, Cheng, Kwan H, Roberts, James L, Viswasam, Nikita, Elaydi, Saber
Published in International journal of molecular sciences (21.04.2020)
Published in International journal of molecular sciences (21.04.2020)
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Data showing the lipid conformations and membrane binding behaviors of beta-amyloid fibrils in phase-separated cholesterol-enriched lipid domains with and without glycolipid and oxidized cholesterol from coarse-grained molecular dynamics simulations
Cheng, Sara Y., Cao, Yiyi, Rouzbehani, Marzieh, Cheng, Kwan H.
Published in Data in brief (01.06.2020)
Published in Data in brief (01.06.2020)
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Coarse-grained MD simulations reveal beta-amyloid fibrils of various sizes bind to interfacial liquid-ordered and liquid-disordered regions in phase separated lipid rafts with diverse membrane-bound conformational states
Cheng, Sara Y., Cao, Yiyi, Rouzbehani, Marzieh, Cheng, Kwan H.
Published in Biophysical chemistry (01.05.2020)
Published in Biophysical chemistry (01.05.2020)
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4,5-Dimethoxy-2-nitrobenzohydrazides and 1-(1-Benzylpiperidin-4-yl)ethan-1-ones as Potential Antioxidant/Cholinergic Endowed Small Molecule Leads
Banu, Rukhsar, Gerding, Jason, Franklin, Cynthia, Sikazwe, Donald, Horton, William, Török, Marianna, Davis, Julian, Cheng, Kwan H, Nakazwe, Muziya, Mochona, Bereket
Published in Scientia pharmaceutica (21.12.2017)
Published in Scientia pharmaceutica (21.12.2017)
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Molecular Dynamics Studies of the Molecular Structure and Interactions of Cholesterol Superlattices and Random Domains in an Unsaturated Phosphatidylcholine Bilayer Membrane
Zhu, Qing, Cheng, Kwan H., Vaughn, Mark W.
Published in The journal of physical chemistry. B (20.09.2007)
Published in The journal of physical chemistry. B (20.09.2007)
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Journal Article
Data supporting beta-amyloid dimer structural transitions and protein–lipid interactions on asymmetric lipid bilayer surfaces using MD simulations on experimentally derived NMR protein structures
Cheng, Sara Y., Chou, George, Buie, Creighton, Vaughn, Mark W., Compton, Campbell, Cheng, Kwan H.
Published in Data in brief (01.06.2016)
Published in Data in brief (01.06.2016)
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Examination of the Interplay between Membrane Tension and the Tight Junction Protein, ZO-1
Wilkinson, Nancy J, Peng, Lindsey N, Doran, John E, Cheng, Kwan H, King, Jonathan M
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Dynamic Fingering in Adhered Lipid Membranes
Shindell, Orrin, Mica, Natalie, Cheng, Kwan H, Wang, Exing, Gordon, Vernita D
Published in Langmuir (17.04.2018)
Published in Langmuir (17.04.2018)
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Journal Article
Maximally asymmetric transbilayer distribution of anionic lipids alters the structure and interaction with lipids of an amyloidogenic protein dimer bound to the membrane surface
Cheng, Sara Y., Chou, George, Buie, Creighton, Vaughn, Mark W., Compton, Campbell, Cheng, Kwan H.
Published in Chemistry and physics of lipids (01.03.2016)
Published in Chemistry and physics of lipids (01.03.2016)
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Journal Article
Luminescence Decay Dynamics and Trace Biomaterials Detection Potential of Surface-Functionalized Nanoparticles
Cheng, Kwan H, Aijmo, Jacob, Ma, Lun, Yao, Mingzhen, Zhang, Xing, Como, John, Hope-Weeks, Louisa J, Huang, Juyang, Chen, Wei
Published in Journal of physical chemistry. C (20.11.2008)
Published in Journal of physical chemistry. C (20.11.2008)
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