BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program
Ren, Decheng, Tu, Ho-Chou, Kim, Hyungjin, Wang, Gary X, Bean, Gregory R, Takeuchi, Osamu, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D, Cheng, Emily H.-Y
Published in Science (American Association for the Advancement of Science) (03.12.2010)
Published in Science (American Association for the Advancement of Science) (03.12.2010)
Get full text
Journal Article
BAX activation is initiated at a novel interaction site
Tjandra, Nico, Walensky, Loren D, Gavathiotis, Evripidis, Suzuki, Motoshi, Davis, Marguerite L, Pitter, Kenneth, Bird, Gregory H, Katz, Samuel G, Tu, Ho-Chou, Kim, Hyungjin, Cheng, Emily H.-Y
Published in Nature (23.10.2008)
Published in Nature (23.10.2008)
Get full text
Journal Article
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
Wei, Michael C., Zong, Wei-Xing, Emily H. -Y. Cheng, Lindsten, Tullia, Panoutsakopoulou, Vily, Ross, Andrea J., Roth, Kevin A., MacGregor, Grant R., Thompson, Craig B., Korsmeyer, Stanley J.
Published in Science (American Association for the Advancement of Science) (27.04.2001)
Published in Science (American Association for the Advancement of Science) (27.04.2001)
Get full text
Journal Article
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
Hsieh, James J.-D, Liu, Han, Takeda, Shugaku, Kumar, Rakesh, Westergard, Todd D, Brown, Eric J, Pandita, Tej K, Cheng, Emily H.-Y
Published in Nature (London) (16.09.2010)
Published in Nature (London) (16.09.2010)
Get full text
Journal Article
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
Chen, Yun, Lewis, William, Diwan, Abhinav, Cheng, Emily H.-Y., Matkovich, Scot J., Dorn, Gerald W., Olson, Eric N.
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
Get full text
Journal Article
PUMA and BIM are required for oncogene inactivation-induced apoptosis
Bean, Gregory R, Ganesan, Yogesh Tengarai, Dong, Yiyu, Takeda, Shugaku, Liu, Han, Chan, Po M, Huang, Yafen, Chodosh, Lewis A, Zambetti, Gerard P, Hsieh, James J-D, Cheng, Emily H-Y
Published in Science signaling (26.03.2013)
Published in Science signaling (26.03.2013)
Get more information
Journal Article
p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage
Tu, Ho-Chou, Ren, Decheng, Wang, Gary X, Chen, David Y, Westergard, Todd D, Kim, Hyungjin, Sasagawa, Satoru, Hsieh, James J.-D, Cheng, Emily H.-Y
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2009)
Get full text
Journal Article
A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth
CHEN, David Y, LEE, Yishan, OH, Kyoung J, KORSMEYER, Stanley J, HERMONE, Ann, GUSSIO, Richard, SHOEMAKER, Robert H, CHENG, Emily H.-Y, HSIEH, James J.-D, VAN TINE, Brian A, SEARLEMAN, Adam C, WESTERGARD, Todd D, HAN LIU, TU, Ho-Chou, TAKEDA, Shugaku, YIYU DONG, PIWNICA-WORMS, David R
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Published in Cancer research (Chicago, Ill.) (01.02.2012)
Get full text
Journal Article
Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression
Takeda, Shugaku, Chen, David Y, Westergard, Todd D, Fisher, Jill K, Rubens, Jeffrey A, Sasagawa, Satoru, Kan, Jason T, Korsmeyer, Stanley J, Cheng, Emily H-Y, Hsieh, James J-D
Published in Genes & development (01.09.2006)
Published in Genes & development (01.09.2006)
Get full text
Journal Article
Conversion of Bcl-2 to a bax-like death effector by caspases
CHENG, E. H.-Y, KIRSCH, D. G, CLEM, R. J, RAVI, R, KASTAN, M. B, BEDI, A, UENO, K, HARDWICK, J. M
Published in Science (American Association for the Advancement of Science) (12.12.1997)
Published in Science (American Association for the Advancement of Science) (12.12.1997)
Get full text
Journal Article
The VDAC2-BAK rheostat controls thymocyte survival
Ren, Decheng, Kim, Hyungjin, Tu, Ho-Chou, Westergard, Todd D, Fisher, Jill K, Rubens, Jeff A, Korsmeyer, Stanley J, Hsieh, James J-D, Cheng, Emily H-Y
Published in Science signaling (25.08.2009)
Published in Science signaling (25.08.2009)
Get more information
Journal Article
Bax and Bak Do Not Exhibit Functional Redundancy in Mediating Radiation-Induced Endothelial Apoptosis in the Intestinal Mucosa
Rotolo, Jimmy A., Ph.D, Maj, Jerzy G., M.D, Feldman, Regina, Ren, Decheng, Ph.D, Haimovitz-Friedman, Adriana, Ph.D, Cordon-Cardo, Carlos, M.D, Cheng, Emily H.-Y., M.D., Ph.D, Kolesnick, Richard, M.D, Fuks, Zvi, M.D
Published in International journal of radiation oncology, biology, physics (01.03.2008)
Published in International journal of radiation oncology, biology, physics (01.03.2008)
Get full text
Journal Article
Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
Karch, Jason, Kwong, Jennifer Q, Burr, Adam R, Sargent, Michelle A, Elrod, John W, Peixoto, Pablo M, Martinez-Caballero, Sonia, Osinska, Hanna, Cheng, Emily H-Y, Robbins, Jeffrey, Kinnally, Kathleen W, Molkentin, Jeffery D
Published in eLife (27.08.2013)
Published in eLife (27.08.2013)
Get full text
Journal Article
A Bcl-2 Homolog Encoded by Kaposi Sarcoma-Associated Virus, Human Herpesvirus 8, Inhibits Apoptosis but does not Heterodimerize with Bax or Bak
Emily H.-Y. Cheng, Nicholas, John, Bellows, David S., Hayward, Gary S., Guo, Hong-Guang, Reitz, Marvin S., Hardwick, J. Marie
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.1997)
Get full text
Journal Article
Occipital glial heterotopia: A rare entity with important clinical considerations
Cheng, Emily YQ, Propst, Evan J., Somers, Gino R., Wolter, Nikolaus E.
Published in Otolaryngology case reports (01.11.2021)
Published in Otolaryngology case reports (01.11.2021)
Get full text
Journal Article
Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis
Chen, David Y, Liu, Han, Takeda, Shugaku, Tu, Ho-Chou, Sasagawa, Satoru, Van Tine, Brian A, Lu, Dongsi, Cheng, Emily H-Y, Hsieh, James J-D
Published in Cancer research (Chicago, Ill.) (01.07.2010)
Published in Cancer research (Chicago, Ill.) (01.07.2010)
Get full text
Journal Article