cGAS in action: Expanding roles in immunity and inflammation
Ablasser, Andrea, Chen, Zhijian J
Published in Science (American Association for the Advancement of Science) (08.03.2019)
Published in Science (American Association for the Advancement of Science) (08.03.2019)
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Journal Article
DNA-induced liquid phase condensation of cGAS activates innate immune signaling
Du, Mingjian, Chen, Zhijian J
Published in Science (American Association for the Advancement of Science) (17.08.2018)
Published in Science (American Association for the Advancement of Science) (17.08.2018)
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Journal Article
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
Zhang, Xu, Shi, Heping, Wu, Jiaxi, Zhang, Xuewu, Sun, Lijun, Chen, Chuo, Chen, Zhijian J.
Published in Molecular cell (25.07.2013)
Published in Molecular cell (25.07.2013)
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Journal Article
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway
Zhang, Xuewu, Bai, Xiao-chen, Chen, Zhijian J.
Published in Immunity (Cambridge, Mass.) (14.07.2020)
Published in Immunity (Cambridge, Mass.) (14.07.2020)
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Journal Article
MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response
Hou, Fajian, Sun, Lijun, Zheng, Hui, Skaug, Brian, Jiang, Qiu-Xing, Chen, Zhijian J.
Published in Cell (05.08.2011)
Published in Cell (05.08.2011)
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Journal Article
Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids
Tan, Xiaojun, Sun, Lijun, Chen, Jueqi, Chen, Zhijian J
Published in Annual review of microbiology (08.09.2018)
Published in Annual review of microbiology (08.09.2018)
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Journal Article
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway
Gui, Xiang, Yang, Hui, Li, Tuo, Tan, Xiaojun, Shi, Peiqing, Li, Minghao, Du, Fenghe, Chen, Zhijian J.
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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Journal Article
Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
Cai, Xin, Chen, Jueqi, Xu, Hui, Liu, Siqi, Jiang, Qiu-Xing, Halfmann, Randal, Chen, Zhijian J.
Published in Cell (13.03.2014)
Published in Cell (13.03.2014)
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Journal Article
Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
Shang, Guijun, Zhang, Conggang, Chen, Zhijian J., Bai, Xiao-chen, Zhang, Xuewu
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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Journal Article
cGAS is essential for cellular senescence
Yang, Hui, Wang, Hanze, Ren, Junyao, Chen, Qi, Chen, Zhijian J.
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
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Journal Article
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
Deng, Liufu, Liang, Hua, Xu, Meng, Yang, Xuanming, Burnette, Byron, Arina, Ainhoa, Li, Xiao-Dong, Mauceri, Helena, Beckett, Michael, Darga, Thomas, Huang, Xiaona, Gajewski, Thomas F., Chen, Zhijian J., Fu, Yang-Xin, Weichselbaum, Ralph R.
Published in Immunity (Cambridge, Mass.) (20.11.2014)
Published in Immunity (Cambridge, Mass.) (20.11.2014)
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Journal Article
cGAS is essential for the antitumor effect of immune checkpoint blockade
Wang, Hua, Hu, Shuiqing, Chen, Xiang, Shi, Heping, Chen, Chuo, Sun, Lijun, Chen, Zhijian J.
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2017)
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