Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4‐mediated calcium entry in microglia
Nguyen, Hai M., Lucente, Jacopo, Chen, Yi‐Je, Cui, Yanjun, Ibrahim, Rania H., Pennington, Michael W., Jin, Lee‐Way, Maezawa, Izumi, Wulff, Heike
Published in Glia (01.11.2020)
Published in Glia (01.11.2020)
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The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion
Chen, Yi‐Je, Cui, Yanjun, Singh, Latika, Wulff, Heike
Published in Annals of clinical and translational neurology (01.10.2021)
Published in Annals of clinical and translational neurology (01.10.2021)
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Computational design of peptides to target NaV1.7 channel with high potency and selectivity for the treatment of pain
Nguyen, Phuong T, Nguyen, Hai M, Wagner, Karen M, Stewart, Robert G, Singh, Vikrant, Thapa, Parashar, Chen, Yi-Je, Lillya, Mark W, Ton, Anh Tuan, Kondo, Richard, Ghetti, Andre, Pennington, Michael W, Hammock, Bruce, Griffith, Theanne N, Sack, Jon T, Wulff, Heike, Yarov-Yarovoy, Vladimir
Published in eLife (28.12.2022)
Published in eLife (28.12.2022)
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Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling
Jian, Zhong, Han, Huilan, Zhang, Tieqiao, Puglisi, Jose, Izu, Leighton T, Shaw, John A, Onofiok, Ekama, Erickson, Jeffery R, Chen, Yi-Je, Horvath, Balazs, Shimkunas, Rafael, Xiao, Wenwu, Li, Yuanpei, Pan, Tingrui, Chan, James, Banyasz, Tamas, Tardiff, Jil C, Chiamvimonvat, Nipavan, Bers, Donald M, Lam, Kit S, Chen-Izu, Ye
Published in Science signaling (18.03.2014)
Published in Science signaling (18.03.2014)
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Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice
Pan, Shiyue, Karey, Emma, Nieves-Cintron, Madeline, Chen, Yi-Je, Hwang, Sung Hee, Hammock, Bruce D, Pinkerton, Kent E, Chen, Chao-Yin
Published in Frontiers in physiology (08.06.2023)
Published in Frontiers in physiology (08.06.2023)
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Intravenous HOE-642 Reduces Brain Edema and Na Uptake in the Rat Permanent Middle Cerebral Artery Occlusion Model of Stroke: Evidence for Participation of the Blood–Brain Barrier Na/H Exchanger
O'Donnell, Martha E, Chen, Yi-Je, Lam, Tina I, Taylor, Kelleen C, Walton, Jeffrey H, Anderson, Steven E
Published in Journal of cerebral blood flow and metabolism (01.02.2013)
Published in Journal of cerebral blood flow and metabolism (01.02.2013)
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Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs
Bruun, Donald A., Ma, Betty, Chen, Yi‐Je, Wu, Chun‐Yi, Aleman, Monica, Zolkowska, Dorota, Smiley‐Jewell, Suzette M., Rogawski, Michael A., Lein, Pamela J.
Published in Epilepsia open (01.06.2023)
Published in Epilepsia open (01.06.2023)
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Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice
Pressly, Brandon, Vasylieva, Natalia, Barnych, Bogdan, Singh, Vikrant, Singh, Latika, Bruun, Donald A., Hwang, Sung Hee, Chen, Yi-Je, Fettinger, James C., Johnnides, Stephanie, Lein, Pamela J., Yang, Jun, Hammock, Bruce D., Wulff, Heike
Published in Archives of toxicology (01.06.2020)
Published in Archives of toxicology (01.06.2020)
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Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice
Sun, Junqing, Pan, Shiyue, Karey, Emma, Chen, Yi-Je, Pinkerton, Kent E., Wilson, Christopher G., Chen, Chao-Yin
Published in Frontiers in physiology (24.09.2021)
Published in Frontiers in physiology (24.09.2021)
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In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models
Jian, Zhong, Chen, Yi-Je, Shimkunas, Rafael, Jian, Yuwen, Jaradeh, Mark, Chavez, Karen, Chiamvimonvat, Nipavan, Tardiff, Jil C, Izu, Leighton T, Ross, Robert S, Chen-Izu, Ye
Published in PloS one (08.08.2016)
Published in PloS one (08.08.2016)
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The Riluzole Derivative 2-Amino-6-trifluoromethylthio-benzothiazole (SKA-19), a Mixed KCa2 Activator and NaV Blocker, is a Potent Novel Anticonvulsant
Coleman, Nichole, Nguyen, Hai M., Cao, Zhengyu, Brown, Brandon M., Jenkins, David Paul, Zolkowska, Dorota, Chen, Yi-Je, Tanaka, Brian S., Goldin, Alan L., Rogawski, Michael A., Pessah, Isaac N., Wulff, Heike
Published in Neurotherapeutics (2015)
Published in Neurotherapeutics (2015)
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The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy
Chen, Yi-Je, Lam, Jenny, Gregory, Clare R, Schrepfer, Sonja, Wulff, Heike
Published in PloS one (29.11.2013)
Published in PloS one (29.11.2013)
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Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion in ischemic stroke
Wulff, Heike, Chen, Yi-Je, Lee, Ruth D., Cui, Yanjun, Singh, Latika
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke
Chen, Yi-Je, Nguyen, Hai M, Maezawa, Izumi, Grössinger, Eva M, Garing, April L, Köhler, Ralf, Jin, Lee-Way, Wulff, Heike
Published in Journal of cerebral blood flow and metabolism (01.12.2016)
Published in Journal of cerebral blood flow and metabolism (01.12.2016)
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Riluzole and novel naphthalenyl substituted aminothiazole derivatives prevent acute neural excitotoxic injury in a rat model of temporal lobe epilepsy
Kyllo, Thomas, Singh, Vikrant, Shim, Heesung, Latika, Singh, Nguyen, Hai M., Chen, Yi-Je, Terry, Ellen, Wulff, Heike, Erickson, Jeffrey D.
Published in Neuropharmacology (15.02.2023)
Published in Neuropharmacology (15.02.2023)
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