Angiopoietin-like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids[S]
Chen, Yan Q., Pottanat, Thomas G., Siegel, Robert W., Ehsani, Mariam, Qian, Yue-Wei, Zhen, Eugene Y., Regmi, Ajit, Roell, William C., Guo, Haihong, Luo, M. Jane, Gimeno, Ruth E., van't Hooft, Ferdinand, Konrad, Robert J.
Published in Journal of lipid research (01.08.2020)
Published in Journal of lipid research (01.08.2020)
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Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity
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Published in Journal of lipid research (01.10.2023)
Published in Journal of lipid research (01.10.2023)
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An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif
Balasubramaniam, Deepa, Schroeder, Oliver, Russell, Anna M., Fitchett, Jonathan R., Austin, Aaron K., Beyer, Thomas P., Chen, Yan Q., Day, Jonathan W., Ehsani, Mariam, Heng, Aik Roy, Zhen, Eugene Y., Davies, Julian, Glaesner, Wolfgang, Jones, Bryan E., Siegel, Robert W., Qian, Yue-Wei, Konrad, Robert J.
Published in Journal of lipid research (01.05.2022)
Published in Journal of lipid research (01.05.2022)
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Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits
Hoffmann, William G., Chen, Yan Q., Schwartz, Charles S., Barber, Jacob L., Dev, Prasun K., Reasons, Riley J., Miranda Maravi, Juan S., Armstrong, Bridget, Gerszten, Robert E., Silbernagel, Günther, Konrad, Robert J., Bouchard, Claude, Sarzynski, Mark A.
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Published in Journal of lipid research (01.02.2024)
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Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure
Cao, Guoqing, Beyer, Thomas P., Zhang, Youyan, Schmidt, Robert J., Chen, Yan Q., Cockerham, Sandra L., Zimmerman, Karen M., Karathanasis, Sotirios K., Cannady, Ellen A., Fields, Todd, Mantlo, Nathan B.
Published in Journal of lipid research (01.12.2011)
Published in Journal of lipid research (01.12.2011)
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Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity
Chen, Yan Q., Pottanat, Thomas G., Siegel, Robert W., Ehsani, Mariam, Qian, Yue-Wei, Konrad, Robert J.
Published in Heliyon (01.09.2021)
Published in Heliyon (01.09.2021)
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Angiopoietin-like proteins and postprandial partitioning of fatty acids
DiDonna, Nicole M, Chen, Yan Q, Konrad, Robert J
Published in Current opinion in lipidology (01.02.2022)
Published in Current opinion in lipidology (01.02.2022)
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Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity
Zhen, Eugene Y, Chen, Yan Q, Russell, Anna M, Ehsani, Mariam, Siegel, Robert W, Qian, Yuewei, Konrad, Robert J
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2023)
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Inverse association between apolipoprotein C-II and cardiovascular mortality: role of lipoprotein lipase activity modulation
Silbernagel, Günther, Chen, Yan Q, Rief, Martin, Kleber, Marcus E, Hoffmann, Michael M, Stojakovic, Tatjana, Stang, Andreas, Sarzynski, Mark A, Bouchard, Claude, März, Winfried, Qian, Yue-Wei, Scharnagl, Hubert, Konrad, Robert J
Published in European heart journal (01.07.2023)
Published in European heart journal (01.07.2023)
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Angiopoietin-like protein 4(E40K) and ANGPTL4/8 complex have reduced, temperature-dependent LPL-inhibitory activity compared to ANGPTL4
Chen, Yan Q., Pottanat, Thomas G., Siegel, Robert W., Ehsani, Mariam, Qian, Yue-Wei, Roell, William C., Konrad, Robert J.
Published in Biochemical and biophysical research communications (01.01.2021)
Published in Biochemical and biophysical research communications (01.01.2021)
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Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality
Silbernagel, Günther, Chen, Yan Q, Li, Hongxia, Lemen, Deven, Wen, Yi, Zhen, Eugene Y, Rief, Martin, Kleber, Marcus E, Delgado, Graciela, Sarzynski, Mark A, Qian, Yue-Wei, Schmidt, Boerge, Erbel, Raimund, Trampisch, Ulrike, Moissl, Angela P, Rudolf, Henrik, Schunkert, Heribert, Stang, Andreas, März, Winfried, Trampisch, Hans J, Scharnagl, Hubert, Konrad, Robert J
Published in Circulation (New York, N.Y.) (11.10.2024)
Published in Circulation (New York, N.Y.) (11.10.2024)
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Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity
Chen, Yan Q, Yang, Ye, Zhen, Eugene Y, Beyer, Thomas P, Li, Hongxia, Wen, Yi, Ehsani, Mariam, Jackson, Nicholas, Xie, Katherine, Jung, Hyesoo, Scheithauer, Julia L, Kumari, Anni, Birrane, Gabriel, Russell, Anna M, Balasubramaniam, Deepa, Liao, Zhongping, Siegel, Robert W, Qian, Yuewei, Ploug, Michael, Young, Stephen G, Konrad, Robert J
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (23.04.2024)
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Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen
Yang, Ye, Beigneux, Anne P, Song, Wenxin, Nguyen, Le Phuong, Jung, Hyesoo, Tu, Yiping, Weston, Thomas A, Tran, Caitlyn M, Xie, Katherine, Yu, Rachel G, Tran, Anh P, Miyashita, Kazuya, Nakajima, Katsuyuki, Murakami, Masami, Chen, Yan Q, Zhen, Eugene Y, Kim, Joonyoung R, Kim, Paul H, Birrane, Gabriel, Tontonoz, Peter, Ploug, Michael, Konrad, Robert J, Fong, Loren G, Young, Stephen G
Published in The Journal of clinical investigation (01.12.2023)
Published in The Journal of clinical investigation (01.12.2023)
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Affinity capture elution bridging assay: A novel immunoassay format for detection of anti-therapeutic protein antibodies
Chen, Yan Q., Pottanat, Thomas G., Carter, Quincy L., Troutt, Jason S., Konrad, Robert J., Sloan, John H.
Published in Journal of immunological methods (01.04.2016)
Published in Journal of immunological methods (01.04.2016)
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Differential mechanisms of plasminogen activator inhibitor-1 gene activation by transforming growth factor-beta and tumor necrosis factor-alpha in endothelial cells
Chen, Y Q, Sloan-Lancaster, J, Berg, D T, Richardson, M A, Grinnell, B, Tseng-Crank, J
Published in Thrombosis and haemostasis (01.12.2001)
Published in Thrombosis and haemostasis (01.12.2001)
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Establishment of a hypertrophic scar model by transplanting full-thickness human skin grafts onto the backs of nude mice
Yang, Dong Y, Li, Shi R, Wu, Ju L, Chen, Yan Q, Li, Gang, Bi, Sheng, Dai, Xia
Published in Plastic and reconstructive surgery (1963) (01.01.2007)
Published in Plastic and reconstructive surgery (1963) (01.01.2007)
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