Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells
Chen, Kuen-Feng, Chen, Hui-Ling, Tai, Wei-Tien, Feng, Wen-Chi, Hsu, Chih-Hung, Chen, Pei-Jer, Cheng, Ann-Lii
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
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Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy
Huang, Tzu-Ting, Su, Jung-Chen, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in International journal of molecular sciences (08.06.2017)
Published in International journal of molecular sciences (08.06.2017)
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Journal Article
Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation
Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in The Journal of biological chemistry (21.06.2013)
Published in The Journal of biological chemistry (21.06.2013)
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Journal Article
Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
Tai, Wei-Tien, Cheng, Ann-Lii, Shiau, Chung-Wai, Huang, Hsiang-Po, Huang, Jui-Wen, Chen, Pei-Jer, Chen, Kuen-Feng
Published in Journal of hepatology (01.11.2011)
Published in Journal of hepatology (01.11.2011)
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Journal Article
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation
Hung, Man-Hsin, Chen, Yao-Li, Chen, Li-Ju, Chu, Pei-Yi, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Shih, Chih-Ting, Chao, Tzu-I, Huang, Chao-Yuan, Chen, Kuen-Feng
Published in Cell death & disease (29.05.2019)
Published in Cell death & disease (29.05.2019)
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Journal Article
Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma
Tai, Wei‐Tien, Chen, Yao‐Li, Chu, Pei‐Yi, Chen, Li‐Ju, Hung, Man‐Hsin, Shiau, Chung‐Wai, Huang, Jui‐Wen, Tsai, Ming‐Hsien, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.05.2016)
Published in Hepatology (Baltimore, Md.) (01.05.2016)
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Journal Article
STAT3 mediates regorafenib-induced apoptosis in hepatocellular carcinoma
Tai, Wei-Tien, Chu, Pei-Yi, Shiau, Chung-Wai, Chen, Yao-Li, Li, Yong-Shi, Hung, Man-Hsin, Chen, Li-Ju, Chen, Pei-Lung, Su, Jung-Chen, Lin, Ping-Yi, Yu, Hui-Chuan, Chen, Kuen-Feng
Published in Clinical cancer research (15.11.2014)
Published in Clinical cancer research (15.11.2014)
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Journal Article
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6‐independent manner
Hsieh, Feng‐Shu, Chen, Yao‐Li, Hung, Man‐Hsin, Chu, Pei‐Yi, Tsai, Ming‐Hsien, Chen, Li‐Ju, Hsiao, Yung‐Jen, Shih, Chih‐Ting, Chang, Mao‐Ju, Chao, Tzu‐I, Shiau, Chung‐Wai, Chen, Kuen‐Feng
Published in Molecular oncology (01.08.2017)
Published in Molecular oncology (01.08.2017)
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Journal Article
Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3
CHEN, Kuen-Feng, TAI, Wei-Tien, LIU, Tsung-Hao, HUANG, Hsiang-Po, LIN, Yu-Chin, SHIAU, Chung-Wai, LI, Pui-Kai, CHEN, Pei-Jer, CHENG, Ann-Lii
Published in Clinical cancer research (01.11.2010)
Published in Clinical cancer research (01.11.2010)
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Journal Article
CIP2A is a target of bortezomib in human triple negative breast cancer cells
Tseng, Ling-Ming, Liu, Chun-Yu, Chang, Kung-Chi, Chu, Pei-Yi, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in Breast cancer research : BCR (26.04.2012)
Published in Breast cancer research : BCR (26.04.2012)
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Journal Article
Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3
Tai, Wei-Tien, Cheng, Ann-Lii, Shiau, Chung-Wai, Liu, Chun-Yu, Ko, Ching-Huai, Lin, Mai-Wei, Chen, Pei-Jer, Chen, Kuen-Feng
Published in Molecular cancer therapeutics (01.02.2012)
Published in Molecular cancer therapeutics (01.02.2012)
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Journal Article
Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells
Liu, Chun-Yu, Hung, Man-Hsin, Wang, Duen-Shian, Chu, Pei-Yi, Su, Jung-Chen, Teng, Tsung-Han, Huang, Chun-Teng, Chao, Ting-Ting, Wang, Cheng-Yi, Shiau, Chung-Wai, Tseng, Ling-Ming, Chen, Kuen-Feng
Published in Breast cancer research : BCR (17.09.2014)
Published in Breast cancer research : BCR (17.09.2014)
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Journal Article
Discovery of novel src homology region 2 domain‐containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma
Tai, Wei‐Tien, Shiau, Chung‐Wai, Chen, Pei‐Jer, Chu, Pei‐Yi, Huang, Hsiang‐Po, Liu, Chun‐Yu, Huang, Jui‐Wen, Chen, Kuen‐Feng
Published in Hepatology (Baltimore, Md.) (01.01.2014)
Published in Hepatology (Baltimore, Md.) (01.01.2014)
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Journal Article
Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition
Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Liu, Chen-Hua, Liu, Chun-Jen, Tai, Wei-Tien, Jeng, Yung-Ming, Yang, Hung-Chih, Tseng, Tai-Chung, Huang, Hsiang-Po, Cheng, Huei-Ru, Chen, Pei-Jer, Chen, Kuen-Feng, Kao, Jia-Horng, Chen, Ding-Shinn
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
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Journal Article
Cancerous inhibitor of protein phosphatase 2A mediates bortezomib-induced autophagy in hepatocellular carcinoma independent of proteasome
Yu, Hui-Chuan, Hou, Duen-Ren, Liu, Chun-Yu, Lin, Chen-Si, Shiau, Chung-Wai, Cheng, Ann-Lii, Chen, Kuen-Feng
Published in PloS one (01.02.2013)
Published in PloS one (01.02.2013)
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Journal Article
Sorafenib Enhances Radiation-Induced Apoptosis in Hepatocellular Carcinoma by Inhibiting STAT3
Huang, Chao-Yuan, MD, PhD, Lin, Chen-Si, PhD, Tai, Wei-Tien, PhD, Hsieh, Chi-Ying, MS, Shiau, Chung-Wai, PhD, Cheng, Ann-Lii, MD, PhD, Chen, Kuen-Feng, MD, PhD
Published in International journal of radiation oncology, biology, physics (01.07.2013)
Published in International journal of radiation oncology, biology, physics (01.07.2013)
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Journal Article
A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy
Chao, Tzu-I, Tai, Wei-Tien, Hung, Man-Hsin, Tsai, Ming-Hsien, Chen, Min-Hsuan, Chang, Mao-Ju, Shiau, Chung-Wai, Chen, Kuen-Feng
Published in Cancer letters (28.02.2016)
Published in Cancer letters (28.02.2016)
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Journal Article
Serine/threonine protein phosphatase 5 is a potential therapeutic target in cholangiocarcinoma
Hu, Ming‐Hung, Huang, Tzu‐Ting, Chao, Tzu‐I, Chen, Li‐Ju, Chen, Yen‐Lin, Tsai, Ming‐Hsien, Liu, Chun‐Yu, Kao, Jia‐Horng, Chen, Kuen‐Feng
Published in Liver international (01.12.2018)
Published in Liver international (01.12.2018)
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Journal Article
OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma
Gao, Ming, Yeh, Pei Yen, Lu, Yen-Shen, Hsu, Chih-Hung, Chen, Kuen-Feng, Lee, Wei-Chung, Feng, Wen-Chi, Chen, Ching-Shih, Kuo, Min-Liang, Cheng, Ann-Lii
Published in Cancer research (Chicago, Ill.) (15.11.2008)
Published in Cancer research (Chicago, Ill.) (15.11.2008)
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