Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III
Geng, Ruishuang, Omar, Akil, Gopal, Suhasini R., Chen, Daniel H.-C., Stepanyan, Ruben, Basch, Martin L., Dinculescu, Astra, Furness, David N., Saperstein, David, Hauswirth, William, Lustig, Lawrence R., Alagramam, Kumar N.
Published in Scientific reports (18.10.2017)
Published in Scientific reports (18.10.2017)
Get full text
Journal Article
A small molecule mitigates hearing loss in a mouse model of Usher syndrome III
Alagramam, Kumar N, Gopal, Suhasini R, Geng, Ruishuang, Chen, Daniel H-C, Nemet, Ina, Lee, Richard, Tian, Guilian, Miyagi, Masaru, Malagu, Karine F, Lock, Christopher J, Esmieu, William R K, Owens, Andrew P, Lindsay, Nicola A, Ouwehand, Krista, Albertus, Faywell, Fischer, David F, Bürli, Roland W, MacLeod, Angus M, Harte, William E, Palczewski, Krzysztof, Imanishi, Yoshikazu
Published in Nature chemical biology (01.06.2016)
Published in Nature chemical biology (01.06.2016)
Get full text
Journal Article
Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein
Gopal, Suhasini R, Chen, Daniel H-C, Chou, Shih-Wei, Zang, Jingjing, Neuhauss, Stephan C F, Stepanyan, Ruben, McDermott, Jr, Brian M, Alagramam, Kumar N
Published in The Journal of neuroscience (15.07.2015)
Published in The Journal of neuroscience (15.07.2015)
Get full text
Journal Article
The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene
Geng, Ruishuang, Melki, Sami, Chen, Daniel H-C, Tian, Guilian, Furness, David N, Oshima-Takago, Tomoko, Neef, Jakob, Moser, Tobias, Askew, Charles, Horwitz, Geoff, Holt, Jeffrey R, Imanishi, Yoshikazu, Alagramam, Kumar N
Published in The Journal of neuroscience (11.07.2012)
Published in The Journal of neuroscience (11.07.2012)
Get full text
Journal Article
Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells
Geng, Ruishuang, Sotomayor, Marcos, Kinder, Kimberly J, Gopal, Suhasini R, Gerka-Stuyt, John, Chen, Daniel H-C, Hardisty-Hughes, Rachel E, Ball, Greg, Parker, Andy, Gaudet, Rachelle, Furness, David, Brown, Steve D, Corey, David P, Alagramam, Kumar N
Published in The Journal of neuroscience (06.03.2013)
Published in The Journal of neuroscience (06.03.2013)
Get full text
Journal Article
Noise exposure immediately activates cochlear mitogen-activated protein kinase signaling
Alagramam, Kumar N, Stepanyan, Ruben, Jamesdaniel, Samson, Chen, Daniel H-C, Davis, Rickie R
Published in Noise & health (01.11.2014)
Published in Noise & health (01.11.2014)
Get full text
Journal Article
Proteomics, bioinformatics and targeted gene expression analysis reveals up-regulation of cochlin and identifies other potential biomarkers in the mouse model for deafness in usher syndrome type 1F
Chance, Mark R., Chang, Jinsook, Liu, Shuqing, Gokulrangan, Giridharan, Chen, Daniel H.-C., Lindsay, Aaron, Geng, Ruishuang, Zheng, Qing Y., Alagramam, Kumar
Published in Human molecular genetics (15.04.2010)
Published in Human molecular genetics (15.04.2010)
Get full text
Journal Article
Expression of Cyclin-Dependent Kinase Inhibitors in Epiphyseal Chondrocytes Induced to Terminally Differentiate with Thyroid Hormone
Ballock, R. Tracy, Zhou, Xiaolan, Mink, Lynn M, Chen, Daniel H. C, Mita, Barry C, Stewart, Matthew C
Published in Endocrinology (Philadelphia) (01.12.2000)
Published in Endocrinology (Philadelphia) (01.12.2000)
Get full text
Journal Article
Gene expression analysis of distinct populations of cells isolated from mouse and human inner ear FFPE tissue using laser capture microdissection – a Technical report based on preliminary findings
Pagedar, Nitin A., Wang, Wen, Chen, Daniel H.-C., Davis, Rickie R., Lopez, Ivan, Wright, Charles G., Alagramam, Kumar N.
Published in Brain research (26.05.2006)
Published in Brain research (26.05.2006)
Get full text
Journal Article
Identification and Characterization of Mouse Cochlear Stem Cells
Yerukhimovich, Michael V., Bai, Lianhua, Chen, Daniel H.-C., Miller, Robert H., Alagramam, Kumar N.
Published in Developmental neuroscience (01.01.2007)
Published in Developmental neuroscience (01.01.2007)
Get full text
Journal Article
Decreased renal expression of the putative calcium oxalate inhibitor Tamm-Horsfall protein in the ethylene glycol rat model of calcium oxalate urolithiasis
Marengo, Susan Ruth, Chen, Daniel H-C, Kaung, Hue-Lee C, Resnick, Martin I, Yang, Lizhu
Published in The Journal of urology (01.05.2002)
Published in The Journal of urology (01.05.2002)
Get more information
Journal Article
Continuous infusion of oxalate by minipumps induces calcium oxalate nephrocalcinosis
Marengo, Susan Ruth, Chen, Daniel H-C, Evan, Andrew P, Sommer, Andre J, Stowe, Nicholas T, Ferguson, Donald G, Resnick, Martin I, MacLennan, Gregory T
Published in Urolithiasis (01.06.2006)
Published in Urolithiasis (01.06.2006)
Get full text
Journal Article