Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps
Zheng, Dinghai, Xia, Zhenfang, Shyu, Ann-Bin, Chen, Chyi-Ying A
Published in Nature structural & molecular biology (01.11.2009)
Published in Nature structural & molecular biology (01.11.2009)
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Journal Article
Deadenylation Is Prerequisite for P-Body Formation and mRNA Decay in Mammalian Cells
Zheng, Dinghai, Ezzeddine, Nader, Chen, Chyi-Ying A., Zhu, Wenmiao, He, Xiangwei, Shyu, Ann-Bin
Published in The Journal of cell biology (14.07.2008)
Published in The Journal of cell biology (14.07.2008)
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Journal Article
Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
Fabian, Marc R., Mathonnet, Géraldine, Sundermeier, Thomas, Mathys, Hansruedi, Zipprich, Jakob T., Svitkin, Yuri V., Rivas, Fabiola, Jinek, Martin, Wohlschlegel, James, Doudna, Jennifer A., Chen, Chyi-Ying A., Shyu, Ann-Bin, Yates, John R., Hannon, Gregory J., Filipowicz, Witold, Duchaine, Thomas F., Sonenberg, Nahum
Published in Molecular cell (24.09.2009)
Published in Molecular cell (24.09.2009)
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Journal Article
Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation
Ezzeddine, Nader, Chang, Tsung-Cheng, Zhu, Wenmiao, Yamashita, Akio, Chen, Chyi-Ying A., Zhong, Zhenping, Yamashita, Yukiko, Zheng, Dinghai, Shyu, Ann-Bin
Published in Molecular and Cellular Biology (01.11.2007)
Published in Molecular and Cellular Biology (01.11.2007)
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Journal Article
ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression
Yoshikawa, Takeshi, Wu, Jianfeng, Otsuka, Motoyuki, Kishikawa, Takahiro, Ohno, Motoko, Shibata, Chikako, Takata, Akemi, Han, Felicia, Kang, Young Jun, Chen, Chyi-Ying A, Shyu, Ann-Bin, Han, Jiahuai, Koike, Kazuhiko
Published in Nucleic acids research (03.09.2015)
Published in Nucleic acids research (03.09.2015)
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Journal Article
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
Winzen, Reinhard, Kracht, Michael, Ritter, Birgit, Wilhelm, Arno, Chen, Chyi-Ying A., Shyu, Ann-Bin, Müller, Monika, Gaestel, Matthias, Resch, Klaus, Holtmann, Helmut
Published in The EMBO journal (15.09.1999)
Published in The EMBO journal (15.09.1999)
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Journal Article
MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1
Chen, Chyi-Ying A, Chang, Jeffrey T, Ho, Yi-Fang, Shyu, Ann-Bin
Published in Nucleic acids research (05.05.2016)
Published in Nucleic acids research (05.05.2016)
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Journal Article
UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant
Chang, Tsung-Cheng, Yamashita, Akio, Chen, Chyi-Ying A, Yamashita, Yukiko, Zhu, Wenmiao, Durdan, Simon, Kahvejian, Avak, Sonenberg, Nahum, Shyu, Ann-Bin
Published in Genes & development (15.08.2004)
Published in Genes & development (15.08.2004)
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Journal Article
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
Peng, Sheila S.-Y., Chen, Chyi-Ying A., Xu, Nianhua, Shyu, Ann-Bin
Published in The EMBO journal (15.06.1998)
Published in The EMBO journal (15.06.1998)
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Journal Article
Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation
Chen, Chyi-Ying A, Strouz, Krista, Huang, Kai-Lieh, Shyu, Ann-Bin
Published in RNA (Cambridge) (01.09.2020)
Published in RNA (Cambridge) (01.09.2020)
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Journal Article
Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization
Chen, Chyi-Ying A., Xu, Nianhua, Shyu, Ann-Bin
Published in Molecular and Cellular Biology (01.10.2002)
Published in Molecular and Cellular Biology (01.10.2002)
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Journal Article
Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation
Zhai, Yuxin, Zhong, Zhenping, Chen, Chyi-Ying A., Xia, Zhenfang, Song, Ling, Blackburn, Michael R., Shyu, Ann-Bin
Published in Molecular and Cellular Biology (01.12.2008)
Published in Molecular and Cellular Biology (01.12.2008)
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Journal Article
Antagonistic actions of two human Pan3 isoforms on global mRNA turnover
Chen, Chyi-Ying A, Zhang, Yueqiang, Xiang, Yu, Han, Leng, Chang, Jeffrey T, Shyu, Ann-Bin
Published in RNA (Cambridge) (01.09.2017)
Published in RNA (Cambridge) (01.09.2017)
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Journal Article
BTG/TOB factors impact deadenylases
Mauxion, Fabienne, Chen, Chyi-Ying A., Séraphin, Bertrand, Shyu, Ann-Bin
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.12.2009)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.12.2009)
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