Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
McLelland, Gian-Luca, Goiran, Thomas, Yi, Wei, Dorval, Geneviève, Chen, Carol X, Lauinger, Nadine D, Krahn, Andrea I, Valimehr, Sepideh, Rakovic, Aleksandar, Rouiller, Isabelle, Durcan, Thomas M, Trempe, Jean-François, Fon, Edward A
Published in eLife (20.04.2018)
Published in eLife (20.04.2018)
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The use of a SOX10 reporter toward ameliorating oligodendrocyte lineage differentiation from human induced pluripotent stem cells
Piscopo, Valerio E. C., Chapleau, Alexandra, Blaszczyk, Gabriela J., Sirois, Julien, You, Zhipeng, Soubannier, Vincent, Chen, Carol X.‐Q., Bernard, Geneviève, Antel, Jack P., Durcan, Thomas M.
Published in Glia (01.06.2024)
Published in Glia (01.06.2024)
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An Inducible Luminescent System to Explore Parkinson's Disease-Associated Genes
Gandy, Anelya, Maussion, Gilles, Al-Habyan, Sara, Nicouleau, Michael, You, Zhipeng, Chen, Carol X-Q, Abdian, Narges, Aprahamian, Nathalia, Krahn, Andrea I, Larocque, Louise, Durcan, Thomas M, Deneault, Eric
Published in International journal of molecular sciences (31.08.2024)
Published in International journal of molecular sciences (31.08.2024)
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Modeling Parkinson's disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines
Bayati, Armin, Ayoubi, Riham, Aguila, Adriana, Zorca, Cornelia E, Deyab, Ghislaine, Han, Chanshuai, Recinto, Sherilyn Junelle, Nguyen-Renou, Emmanuelle, Rocha, Cecilia, Maussion, Gilles, Luo, Wen, Shlaifer, Irina, Banks, Emily, McDowell, Ian, Del Cid Pellitero, Esther, Ding, Xue Er, Sharif, Behrang, Séguéla, Philippe, Yaqubi, Moein, Chen, Carol X-Q, You, Zhipeng, Abdian, Narges, McBride, Heidi M, Fon, Edward A, Stratton, Jo Anne, Durcan, Thomas M, Nahirney, Patrick C, McPherson, Peter S
Published in Nature neuroscience (08.10.2024)
Published in Nature neuroscience (08.10.2024)
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SH3 Domains from a Subset of BAR Proteins Define a Ubl-Binding Domain and Implicate Parkin in Synaptic Ubiquitination
Trempe, Jean-François, Chen, Carol X.-Q., Grenier, Karl, Camacho, Edna Matta, Kozlov, Guennadi, McPherson, Peter S., Gehring, Kalle, Fon, Edward A.
Published in Molecular cell (24.12.2009)
Published in Molecular cell (24.12.2009)
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An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders
Dorion, Marie-France, Casas, Diana, Shlaifer, Irina, Yaqubi, Moein, Fleming, Peter, Karpilovsky, Nathan, Chen, Carol X-Q, Nicouleau, Michael, Piscopo, Valerio E C, MacDougall, Emma J, Alluli, Aeshah, Goldsmith, Taylor M, Schneider, Alexandria, Dorion, Samuel, Aprahamian, Nathalia, MacDonald, Adam, Thomas, Rhalena A, Dudley, Roy W R, Hall, Jeffrey A, Fon, Edward A, Antel, Jack P, Stratton, Jo Anne, Durcan, Thomas M, La Piana, Roberta, Healy, Luke M
Published in Molecular neurodegeneration (05.04.2024)
Published in Molecular neurodegeneration (05.04.2024)
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Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients’ iPSC-Derived Models
Maussion, Gilles, Rocha, Cecilia, Abdian, Narges, Yang, Dimitri, Turk, Julien, Carrillo Valenzuela, Dulce, Pimentel, Luisa, You, Zhipeng, Morquette, Barbara, Nicouleau, Michael, Deneault, Eric, Higgins, Samuel, Chen, Carol X.-Q., Reintsch, Wolfgang E., Ho, Stanley, Soubannier, Vincent, Lépine, Sarah, Modrusan, Zora, Lund, Jessica, Stephenson, William, Schubert, Rajib, Durcan, Thomas M.
Published in International journal of molecular sciences (01.10.2023)
Published in International journal of molecular sciences (01.10.2023)
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An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
Castellanos-Montiel, María José, Chaineau, Mathilde, Franco-Flores, Anna Kristyna, Haghi, Ghazal, Carrillo-Valenzuela, Dulce, Reintsch, Wolfgang E, Chen, Carol X-Q, Durcan, Thomas M
Published in Cells (Basel, Switzerland) (08.02.2023)
Published in Cells (Basel, Switzerland) (08.02.2023)
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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
Laflamme, Carl, McKeever, Paul M, Kumar, Rahul, Schwartz, Julie, Kolahdouzan, Mahshad, Chen, Carol X, You, Zhipeng, Benaliouad, Faiza, Gileadi, Opher, McBride, Heidi M, Durcan, Thomas M, Edwards, Aled M, Healy, Luke M, Robertson, Janice, McPherson, Peter S
Published in eLife (15.10.2019)
Published in eLife (15.10.2019)
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Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels
Joch, Monica, Ase, Ariel R, Chen, Carol X-Q, MacDonald, Penny A, Kontogiannea, Maria, Corera, Amadou T, Brice, Alexis, Séguéla, Philippe, Fon, Edward A
Published in Molecular biology of the cell (01.08.2007)
Published in Molecular biology of the cell (01.08.2007)
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Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing
Chen, Carol X.-Q., You, Zhipeng, Abdian, Narges, Sirois, Julien, Shlaifer, Irina, Tabatabaei, Mahdieh, Boivin, Marie-Noëlle, Gaborieau, Lydiane, Karamchandani, Jason, Beitel, Lenore K., Fon, Edward A., Durcan, Thomas M.
Published in Stem cell research (01.07.2022)
Published in Stem cell research (01.07.2022)
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Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons
Lépine, Sarah, Nauleau-Javaudin, Angela, Deneault, Eric, Chen, Carol X.-Q., Abdian, Narges, Franco-Flores, Anna Krystina, Haghi, Ghazal, Castellanos-Montiel, María José, Maussion, Gilles, Chaineau, Mathilde, Durcan, Thomas Martin
Published in iScience (15.03.2024)
Published in iScience (15.03.2024)
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CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids
Thomas, Rhalena A., Sirois, Julien, Li, Shuming, Gestin, Alexandre, Deyab, Ghislaine, Piscopo, Valerio E.C., Lépine, Paula, Mathur, Meghna, Chen, Carol X.-Q., Soubannier, Vincent, Goldsmith, Taylor M., Fawaz, Lama, Durcan, Thomas M., Fon, Edward A.
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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Nanotherapeutic Modulation of Human Neural Cells and Glioblastoma in Organoids and Monocultures
Zhang, Issan, Lépine, Paula, Han, Chanshuai, Lacalle-Aurioles, María, Chen, Carol X-Q, Haag, Rainer, Durcan, Thomas M, Maysinger, Dusica
Published in Cells (Basel, Switzerland) (07.11.2020)
Published in Cells (Basel, Switzerland) (07.11.2020)
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Auto-qPCR; a python-based web app for automated and reproducible analysis of qPCR data
Maussion, Gilles, Thomas, Rhalena A., Demirova, Iveta, Gu, Gracia, Cai, Eddie, Chen, Carol X.-Q., Abdian, Narges, Strauss, Theodore J. P., Kelaï, Sabah, Nauleau-Javaudin, Angela, Beitel, Lenore K., Ramoz, Nicolas, Gorwood, Philip, Durcan, Thomas M.
Published in Scientific reports (29.10.2021)
Published in Scientific reports (29.10.2021)
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A Multistep Workflow to Evaluate Newly Generated iPSCs and Their Ability to Generate Different Cell Types
Chen, Carol X.-Q., Abdian, Narges, Maussion, Gilles, Thomas, Rhalena A., Demirova, Iveta, Cai, Eddie, Tabatabaei, Mahdieh, Beitel, Lenore K., Karamchandani, Jason, Fon, Edward A., Durcan, Thomas M.
Published in Methods and protocols (19.07.2021)
Published in Methods and protocols (19.07.2021)
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The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons
Thomas, Rhalena A, Gibon, Julien, Chen, Carol X Q, Chierzi, Sabrina, Soubannier, Vincent G, Baulac, Stephanie, Séguéla, Philippe, Murai, Keith, Barker, Philip A
Published in eNeuro (01.07.2018)
Published in eNeuro (01.07.2018)
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A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis
Deneault, Eric, Chaineau, Mathilde, Nicouleau, Michael, Castellanos Montiel, Maria José, Franco Flores, Anna Kristyna, Haghi, Ghazal, Chen, Carol X.-Q., Abdian, Narges, Shlaifer, Irina, Beitel, Lenore K., Durcan, Thomas M.
Published in Methods (San Diego, Calif.) (01.07.2022)
Published in Methods (San Diego, Calif.) (01.07.2022)
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