Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis
Poon, Michael M., Lorrain, Kym I., Stebbins, Karin J., Edu, Geraldine C., Broadhead, Alexander R., Lorenzana, Ariana O., Paulson, Bryanna E., Baccei, Christopher S., Roppe, Jeffrey R., Schrader, Thomas O., Valdez, Lino J., Xiong, Yifeng, Chen, Austin C., Lorrain, Daniel S.
Published in Scientific reports (08.05.2024)
Published in Scientific reports (08.05.2024)
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Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis
Poon, Michael M, Lorrain, Kym I, Stebbins, Karin J, Edu, Geraldine C, Broadhead, Alexander R, Lorenzana, Ariana J, Roppe, Jeffrey R, Baccei, Jill M, Baccei, Christopher S, Chen, Austin C, Green, Ari J, Lorrain, Daniel S, Chan, Jonah R
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
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Journal Article
Chiral bidentate N-heterocyclic carbene complexes of Rh and Pd
Ren, Li, Chen, Austin C, Decken, Andreas, Crudden, Cathleen M
Published in Canadian journal of chemistry (01.12.2004)
Published in Canadian journal of chemistry (01.12.2004)
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Journal Article
Rhodium Carbene Complexes: Highly Selective Catalysts for the Hydroformylation of Styrene Derivatives
Chen, Austin C, Ren, Li, Decken, Andreas, Crudden, Cathleen M
Published in Organometallics (04.09.2000)
Published in Organometallics (04.09.2000)
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Catalytic asymmetric carbon-carbon bond forming reactions: preparation of optically enriched 2-aryl propionic acids by a catalytic asymmetric hydroboration-homologation sequence
Chen, AC, Ren, L, Crudden, CM
Published in Chemical communications (Cambridge, England) (07.04.1999)
Published in Chemical communications (Cambridge, England) (07.04.1999)
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Year of Publication 23.02.2012
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Year of Publication 22.11.2011
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Renin inhibitors
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Year of Publication 16.06.2011
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RENIN INHIBITORS
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Year of Publication 04.08.2010
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Renin Inhibitors
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Year of Publication 12.11.2009
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Year of Publication 12.11.2009
Patent