Comparison of a thymine challenge test and endogenous uracil–dihydrouracil levels for assessment of fluoropyrimidine toxicity risk
Burns, Kathryn E., Chavani, Ottiniel, Jeong, Soo Hee, Duley, John A., Porter, David, Findlay, Michael, Strother, R. Matthew, Helsby, Nuala A.
Published in Cancer chemotherapy and pharmacology (01.05.2021)
Published in Cancer chemotherapy and pharmacology (01.05.2021)
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Journal Article
Severe 5-Fluorouracil-Associated Gastrointestinal Toxicity Unexplained by Dihydropyrimidine Dehydrogenase Deficiency and Renal Impairment: Should We Be Investigating Other Elimination Pathways to Assess the Risk of 5-Fluorouracil Toxicity?
Jeong, Soo Hee, Chavani, Ottiniel, Burns, Kathryn, Porter, David, Findlay, Michael, Helsby, Nuala
Published in European journal of drug metabolism and pharmacokinetics (01.11.2021)
Published in European journal of drug metabolism and pharmacokinetics (01.11.2021)
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Development, validation and application of a novel liquid chromatography tandem mass spectrometry assay measuring uracil, 5,6-dihydrouracil, 5-fluorouracil, 5,6-dihydro-5-fluorouracil, α-fluoro-β-ureidopropionic acid and α-fluoro-β-alanine in human plasma
Chavani, Ottiniel, Jensen, Berit Packert, Strother, R. Matthew, Florkowski, Christopher M., George, Peter M.
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
Published in Journal of pharmaceutical and biomedical analysis (05.08.2017)
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Journal Article