Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice
Chao, Xiaojuan, Wang, Shaogui, Zhao, Katrina, Li, Yuan, Williams, Jessica A., Li, Tiangang, Chavan, Hemantkumar, Krishnamurthy, Partha, He, Xi C., Li, Linheng, Ballabio, Andrea, Ni, Hong-Min, Ding, Wen-Xing
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2018)
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Journal Article
Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression
Kumar, Dhruv, New, Jacob, Vishwakarma, Vikalp, Joshi, Radhika, Enders, Jonathan, Lin, Fangchen, Dasari, Sumana, Gutierrez, Wade R, Leef, George, Ponnurangam, Sivapriya, Chavan, Hemantkumar, Ganaden, Lydia, Thornton, Mackenzie M, Dai, Hongying, Tawfik, Ossama, Straub, Jeffrey, Shnayder, Yelizaveta, Kakarala, Kiran, Tsue, Terance Ted, Girod, Douglas A, Van Houten, Bennett, Anant, Shrikant, Krishnamurthy, Partha, Thomas, Sufi Mary
Published in Cancer research (Chicago, Ill.) (15.07.2018)
Published in Cancer research (Chicago, Ill.) (15.07.2018)
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Journal Article
Lack of Toxicity in Nonhuman Primates Receiving Clinically Relevant Doses of an AAV9.U7snRNA Vector Designed to Induce DMD Exon 2 Skipping
Gushchina, Liubov V, Frair, Emma C, Rohan, Natalie, Bradley, Adrienne J, Simmons, Tabatha R, Chavan, Hemantkumar D, Chou, Hsin-Jung, Eggers, Michelle, Waldrop, Megan A, Wein, Nicolas, Flanigan, Kevin M
Published in Human gene therapy (01.09.2021)
Published in Human gene therapy (01.09.2021)
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Journal Article
Polycyclic Aromatic Hydrocarbons (PAHs) Mediate Transcriptional Activation of the ATP Binding Cassette Transporter ABCB6 Gene via the Aryl Hydrocarbon Receptor (AhR)
Chavan, Hemantkumar, Krishnamurthy, Partha
Published in The Journal of biological chemistry (14.09.2012)
Published in The Journal of biological chemistry (14.09.2012)
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Journal Article
Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice
Wang, Hua, Ni, Hong-Min, Chao, Xiaojuan, Ma, Xiaowen, Rodriguez, Yssa Ann, Chavan, Hemantkumar, Wang, Shaogui, Krishnamurthy, Partha, Dobrowsky, Rick, Xu, De-Xiang, Jaeschke, Hartmut, Ding, Wen-Xing
Published in Redox biology (01.04.2019)
Published in Redox biology (01.04.2019)
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Journal Article
Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism
Liu, Xing, Lu, Yuanfu, Guan, Xinfu, Dong, Bingning, Chavan, Hemantkumar, Wang, Jin, Zhang, Yiqing, Krishnamurthy, Partha, Li, Feng
Published in Biochemical pharmacology (01.09.2015)
Published in Biochemical pharmacology (01.09.2015)
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Journal Article
Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice
Bhushan, Bharat, Chavan, Hemantkumar, Borude, Prachi, Xie, Yuchao, Du, Kuo, McGill, Mitchell R, Lebofsky, Margitta, Jaeschke, Hartmut, Krishnamurthy, Partha, Apte, Udayan
Published in Toxicological sciences (01.02.2017)
Published in Toxicological sciences (01.02.2017)
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Journal Article
Efficient Purification and Reconstitution of ATP Binding Cassette Transporter B6 (ABCB6) for Functional and Structural Studies
Chavan, Hemantkumar, Taimur Khan, Mohiuddin Md, Tegos, George, Krishnamurthy, Partha
Published in The Journal of biological chemistry (02.08.2013)
Published in The Journal of biological chemistry (02.08.2013)
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Journal Article
Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction
Du, Kuo, Ramachandran, Anup, Weemhoff, James L, Chavan, Hemantkumar, Xie, Yuchao, Krishnamurthy, Partha, Jaeschke, Hartmut
Published in Toxicological sciences (01.12.2016)
Published in Toxicological sciences (01.12.2016)
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Journal Article
A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6
Polireddy, Kishore, Khan, Mohiuddin Md Taimur, Chavan, Hemantkumar, Young, Susan, Ma, Xiaochao, Waller, Anna, Garcia, Matthew, Perez, Dominique, Chavez, Stephanie, Strouse, Jacob J, Haynes, Mark K, Bologa, Cristian G, Oprea, Tudor I, Tegos, George P, Sklar, Larry A, Krishnamurthy, Partha
Published in PloS one (10.07.2012)
Published in PloS one (10.07.2012)
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Journal Article
Proteomic analysis of wild type and arsenite-resistant Leishmania donovani
Sharma, Shruti, Singh, Gaganmeet, Chavan, Hemantkumar D., Dey, Chinmoy S.
Published in Experimental parasitology (01.12.2009)
Published in Experimental parasitology (01.12.2009)
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Journal Article
Confocal microscopic investigation of tubulin distribution and effect of paclitaxel on posttranslationally modified tubulins in sodium arsenite resistant Leishmania donovani
Chavan, Hemantkumar D., Singh, Gaganmeet, Dey, Chinmoy S.
Published in Experimental parasitology (01.07.2007)
Published in Experimental parasitology (01.07.2007)
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Journal Article
Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1
Li, Jibiao, Wang, Yifeng, Matye, David J., Chavan, Hemantkumar, Krishnamurthy, Partha, Li, Feng, Li, Tiangang
Published in The Journal of biological chemistry (06.01.2017)
Published in The Journal of biological chemistry (06.01.2017)
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Journal Article
In Vitro and In Vivo Specificity and Biodistribution of a Novel CD8-Targeted Fusosome
Chavan, Hemantkumar, Amatya, Shirisha, Berlfein, Valeria, Cruite, Patricia, Chaturvedi, Vandana, Vagin, Vasily, van Hoeven, Neal, Shah, Jagesh, Fry, Terry J., Gorovits, Boris, Chandra, Sundeep
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription
Kumar, Ram P, Ray, Soma, Home, Pratik, Saha, Biswarup, Bhattacharya, Bhaswati, Wilkins, Heather M, Chavan, Hemantkumar, Ganguly, Avishek, Milano-Foster, Jessica, Paul, Arindam, Krishnamurthy, Partha, Swerdlow, Russell H, Paul, Soumen
Published in Development (Cambridge) (01.10.2018)
Published in Development (Cambridge) (01.10.2018)
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Journal Article
Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer
Li, Changlin, He, Chenchen, Xu, Ying, Xu, Haixia, Tang, Yuzhe, Chavan, Hemantkumar, Duan, Shaofeng, Artigues, Antonio, Forrest, Marcus Laird, Krishnamurthy, Partha, Han, Suxia, Holzbeierlein, Jeffrey M., Li, Benyi
Published in The Prostate (01.05.2019)
Published in The Prostate (01.05.2019)
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Journal Article
Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice
Qin, Xuan, Hakenjos, John M, MacKenzie, Kevin R, Barzi, Mercedes, Chavan, Hemantkumar, Nyshadham, Pranavanand, Wang, Jin, Jung, Sung Yun, Guner, Joie Z, Chen, Si, Guo, Lei, Krishnamurthy, Partha, Bissig, Karl-Dimiter, Palmer, Stephen, Matzuk, Martin M, Li, Feng
Published in Drug metabolism and disposition (01.02.2022)
Published in Drug metabolism and disposition (01.02.2022)
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