Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
Chaurasia, Bhagirath, Tippetts, Trevor S, Mayoral Monibas, Rafael, Liu, Jinqi, Li, Ying, Wang, Liping, Wilkerson, Joseph L, Sweeney, C Rufus, Pereira, Renato Felipe, Sumida, Doris Hissako, Maschek, J Alan, Cox, James E, Kaddai, Vincent, Lancaster, Graeme Iain, Siddique, Monowarul Mobin, Poss, Annelise, Pearson, Mackenzie, Satapati, Santhosh, Zhou, Heather, McLaren, David G, Previs, Stephen F, Chen, Ying, Qian, Ying, Petrov, Aleksandr, Wu, Margaret, Shen, Xiaolan, Yao, Jun, Nunes, Christian N, Howard, Andrew D, Wang, Liangsu, Erion, Mark D, Rutter, Jared, Holland, William L, Kelley, David E, Summers, Scott A
Published in Science (American Association for the Advancement of Science) (26.07.2019)
Published in Science (American Association for the Advancement of Science) (26.07.2019)
Get full text
Journal Article
Adipocyte Ceramides-The Nexus of Inflammation and Metabolic Disease
Chaurasia, Bhagirath, Talbot, Chad Lamar, Summers, Scott A
Published in Frontiers in immunology (23.09.2020)
Published in Frontiers in immunology (23.09.2020)
Get full text
Journal Article
Ceramides in Adipose Tissue
Li, Ying, Talbot, Chad Lamar, Chaurasia, Bhagirath
Published in Frontiers in endocrinology (Lausanne) (19.06.2020)
Published in Frontiers in endocrinology (Lausanne) (19.06.2020)
Get full text
Journal Article
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C, Ruud, Johan, Nguyen, Khoa D, Theurich, Sebastian, Hausen, A Christine, Schmitz, Joel, Brönneke, Hella S, Estevez, Emma, Allen, Tamara L, Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A, Chawla, Ajay, Wunderlich, F Thomas, Brüning, Jens C
Published in Nature immunology (01.05.2014)
Published in Nature immunology (01.05.2014)
Get full text
Journal Article
Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity
Jais, Alexander, Solas, Maite, Backes, Heiko, Chaurasia, Bhagirath, Kleinridders, André, Theurich, Sebastian, Mauer, Jan, Steculorum, Sophie M., Hampel, Brigitte, Goldau, Julia, Alber, Jens, Förster, Carola Y., Eming, Sabine A., Schwaninger, Markus, Ferrara, Napoleone, Karsenty, Gerard, Brüning, Jens C.
Published in Cell (05.05.2016)
Published in Cell (05.05.2016)
Get full text
Journal Article
Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice
Charron, Maureen J, Williams, Lyda, Seki, Yoshinori, Du, Xiu Quan, Chaurasia, Bhagirath, Saghatelian, Alan, Summers, Scott A, Katz, Ellen B, Vuguin, Patricia M, Reznik, Sandra E
Published in Diabetes (New York, N.Y.) (01.08.2020)
Published in Diabetes (New York, N.Y.) (01.08.2020)
Get full text
Journal Article
Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk
Cai, Jinjin, Pires, Karla M., Ferhat, Maroua, Chaurasia, Bhagirath, Buffolo, Márcio A., Smalling, Rana, Sargsyan, Ashot, Atkinson, Donald L., Summers, Scott A., Graham, Timothy E., Boudina, Sihem
Published in Cell reports (Cambridge) (13.11.2018)
Published in Cell reports (Cambridge) (13.11.2018)
Get full text
Journal Article
Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
Li, Ying, Talbot, Chad Lamar, Chandravanshi, Bhawna, Ksiazek, Alec, Sood, Ayushi, Chowdhury, Kamrul Hasan, Maschek, J. Alan, Cox, James, Babu, Adhini Kuppuswamy Satheesh, Paz, Henry A., Babu, Pon Velayutham Anandh, Meyerholz, David K., Wankhade, Umesh D., Holland, William, Shyong Tai, E., Summers, Scott A., Chaurasia, Bhagirath
Published in Scientific reports (04.05.2022)
Published in Scientific reports (04.05.2022)
Get full text
Journal Article
Editorial: Adipose Tissue in Obesity and Metabolic Disease
Keshvari, Sahar, Ceddia, Ryan P, Rajbhandari, Prashant, Chaurasia, Bhagirath, Bond, Simon T
Published in Frontiers in physiology (19.04.2022)
Published in Frontiers in physiology (19.04.2022)
Get full text
Journal Article
Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes
Chaurasia, Bhagirath, Ying, Li, Talbot, Chad Lamar, Maschek, John Alan, Cox, James, Schuchman, Edward H., Hirabayashi, Yoshio, Holland, William L., Summers, Scott A.
Published in Molecular metabolism (Germany) (01.03.2021)
Published in Molecular metabolism (Germany) (01.03.2021)
Get full text
Journal Article
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
Mauer, Jan, Chaurasia, Bhagirath, Plum, Leona, Quast, Thomas, Hampel, Brigitte, Blüher, Matthias, Kolanus, Waldemar, Kahn, C Ronald, Brüning, Jens C
Published in PLoS genetics (06.05.2010)
Published in PLoS genetics (06.05.2010)
Get full text
Journal Article
Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling
Buffolo, Márcio, Pires, Karla Maria, Ferhat, Maroua, Ilkun, Olesya, Makaju, Aman, Achenbach, Alan, Bowman, Faith, Atkinson, Donald L., Holland, William L., Amri, Ez-Zoubir, Chaurasia, Bhagirath, Franklin, Sarah, Boudina, Sihem
Published in Cell reports (Cambridge) (08.10.2019)
Published in Cell reports (Cambridge) (08.10.2019)
Get full text
Journal Article
Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF-κB Activation in Macrophages
Chaurasia, Bhagirath, Mauer, Jan, Koch, Linda, Goldau, Julia, Kock, Anja-Sterner, Brüning, Jens C.
Published in Molecular and Cellular Biology (01.09.2010)
Published in Molecular and Cellular Biology (01.09.2010)
Get full text
Journal Article
Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice
Wunderlich, Claudia M, Delić, Denis, Behnke, Kristina, Meryk, Andreas, Ströhle, Peter, Chaurasia, Bhagirath, Al-Quraishy, Saleh, Wunderlich, Frank, Brüning, Jens C, Wunderlich, F Thomas
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
Get full text
Journal Article
FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection
Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon
Published in Physiological reports (01.09.2019)
Published in Physiological reports (01.09.2019)
Get full text
Journal Article
Ceramides – Lipotoxic Inducers of Metabolic Disorders
Chaurasia, Bhagirath, Summers, Scott A
Published in Trends in endocrinology and metabolism (01.10.2015)
Published in Trends in endocrinology and metabolism (01.10.2015)
Get full text
Journal Article
Metabolic Messengers: ceramides
Summers, Scott A, Chaurasia, Bhagirath, Holland, William L
Published in Nature metabolism (01.11.2019)
Published in Nature metabolism (01.11.2019)
Get more information
Journal Article
Dihydroceramides: From Bit Players to Lead Actors
Siddique, Monowarul Mobin, Li, Ying, Chaurasia, Bhagirath, Kaddai, Vincent A., Summers, Scott A.
Published in The Journal of biological chemistry (19.06.2015)
Published in The Journal of biological chemistry (19.06.2015)
Get full text
Journal Article