mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Chaudhary, Namit, Weissman, Drew, Whitehead, Kathryn A
Published in Nature reviews. Drug discovery (01.11.2021)
Published in Nature reviews. Drug discovery (01.11.2021)
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Journal Article
A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
Hajj, Khalid A, Melamed, Jilian R, Chaudhary, Namit, Lamson, Nicholas G, Ball, Rebecca L, Yerneni, Saigopalakrishna S, Whitehead, Kathryn A
Published in Nano letters (08.07.2020)
Published in Nano letters (08.07.2020)
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Journal Article
Characterization and comparison of human and mouse milk cells
Doerfler, Rose, Yerneni, Saigopalakrishna, Newby, Alexandra, Chaudhary, Namit, Shu, Ashley, Fein, Katherine, Hofstatter Azambuja, Juliana, Whitehead, Kathryn A
Published in PloS one (31.01.2024)
Published in PloS one (31.01.2024)
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Journal Article
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs
LoPresti, Samuel T., Arral, Mariah L., Chaudhary, Namit, Whitehead, Kathryn A.
Published in Journal of controlled release (01.05.2022)
Published in Journal of controlled release (01.05.2022)
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Journal Article
Non-Viral RNA Delivery During Pregnancy: Opportunities and Challenges
Chaudhary, Namit, Newby, Alexandra N, Whitehead, Kathryn A
Published in Small (Weinheim an der Bergstrasse, Germany) (25.12.2023)
Published in Small (Weinheim an der Bergstrasse, Germany) (25.12.2023)
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Journal Article
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilities targeted mRNA delivery to the spleen and lungs
LoPresti, Samuel T., Arral, Mariah L., Chaudhary, Namit, Whitehead, Kathryn A.
Published in Journal of controlled release (26.03.2022)
Published in Journal of controlled release (26.03.2022)
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Journal Article
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology
Gleeson, John P., Fein, Katherine C., Chaudhary, Namit, Doerfler, Rose, Newby, Alexandra N., Whitehead, Kathryn A.
Published in International journal of pharmaceutics (25.01.2021)
Published in International journal of pharmaceutics (25.01.2021)
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Journal Article
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery
Melamed, Jilian R., Hajj, Khalid A., Chaudhary, Namit, Strelkova, Daria, Arral, Mariah L., Pardi, Norbert, Alameh, Mohamad-Gabriel, Miller, Jason B., Farbiak, Lukas, Siegwart, Daniel J., Weissman, Drew, Whitehead, Kathryn A.
Published in Journal of controlled release (01.01.2022)
Published in Journal of controlled release (01.01.2022)
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Journal Article
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism
Strelkova Petersen, Daria M., Chaudhary, Namit, Arral, Mariah L., Weiss, Ryan M., Whitehead, Kathryn A.
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2023)
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2023)
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Journal Article
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes
Chaudhary, Namit, Newby, Alexandra N, Arral, Mariah L, Yerneni, Saigopalakrishna S, LoPresti, Samuel T, Doerfler, Rose, Petersen, Daria M Strelkova, Montoya, Catalina, Kim, Julie S, Fox, Bethany, Coon, Tiffany, Malaney, Angela, Sadovsky, Yoel, Whitehead, Kathryn A
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
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Journal Article
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
Melamed, Jilian R, Yerneni, Saigopalakrishna S, Arral, Mariah L, LoPresti, Samuel T, Chaudhary, Namit, Sehrawat, Anuradha, Muramatsu, Hiromi, Alameh, Mohamad-Gabriel, Pardi, Norbert, Weissman, Drew, Gittes, George K, Whitehead, Kathryn A
Published in Science advances (27.01.2023)
Published in Science advances (27.01.2023)
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Journal Article
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery
Lamson, Nicholas G, Fein, Katherine C, Gleeson, John P, Newby, Alexandra N, Xian, Sijie, Cochran, Kyle, Chaudhary, Namit, Melamed, Jilian R, Ball, Rebecca L, Suri, Kanika, Ahuja, Vishal, Zhang, Anna, Berger, Adrian, Kolodieznyi, Dmytro, Schmidt, Brigitte F, Silva, Gloria L, Whitehead, Kathryn A
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2022)
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Journal Article
Factor XII Silencing Using siRNA Prevents Thrombus Formation in a Rat Model of Extracorporeal Life Support
Umei, Nao, Shin, Suji, Lai, Angela, Miller, Jennifer, Roberts, Kalliope, Strelkova, Daria, Chaudhary, Namit, Ichiba, Shingo, Sakamoto, Atsuhiro, Whitehead, Kathryn, Cook, Keith
Published in ASAIO journal (1992) (01.06.2023)
Published in ASAIO journal (1992) (01.06.2023)
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Journal Article
Branched‐Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice
Petersen, Daria M. Strelkova, Weiss, Ryan M., Hajj, Khalid A., Yerneni, Saigopalakrishna S., Chaudhary, Namit, Newby, Alexandra N., Arral, Mariah L., Whitehead, Kathryn A.
Published in Advanced healthcare materials (01.09.2024)
Published in Advanced healthcare materials (01.09.2024)
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Journal Article
Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines
Meany, Emily L, Klich, John H, Jons, Carolyn K, Mao, Tianyang, Chaudhary, Namit, Utz, Ashley, Baillet, Julie, Song, Ye E, Saouaf, Olivia M, Ou, Ben S, Williams, Shoshana C, Eckman, Noah, Irvine, Darrell J, Appel, Eric
Published in bioRxiv (10.07.2024)
Published in bioRxiv (10.07.2024)
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Journal Article
From Farm to Pharmacy: Strawberry-Enabled Oral Delivery of Protein Drugs
Lamson, Nicholas G, Fein, Katherine C, Gleeson, John P, Sijie Xian, Newby, Alexandra, Chaudhary, Namit, Melamed, Jilian R, Cochran, Kyle, Ball, Rebecca L, Suri, Kanika, Ahuja, Vishal, Zhang, Anna, Berger, Adrian, Kolodieznyi, Dmytro, Schmidt, Brigitte F, Silva, Gloria L, Whitehead, Kathryn A
Published in bioRxiv (12.03.2020)
Published in bioRxiv (12.03.2020)
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